70 research outputs found
Argyrophilic nucleolar organizer region in proliferating cell has a predictive value for local recurrence in superficial bladder tumor
1999【要旨】Joint authors: Toru Shimazui ... [et al.]Offprint. Originally published: The Journal of Urology, v. 162, pp. 63-68, 199
表在性膀胱腫瘍において増殖期細胞の好銀性核小体形成体関連蛋白は再発の予測因子として有用である
筑波大学University of Tsukuba博士(医学)Doctor of Philosophy in Medical Sciences1999【要旨】Joint authors: Toru Shimazui ... [et al.]Offprint. Originally published: The Journal of Urology, v. 162, pp. 63-68, 1999thesi
A case of gas gangrene in a vesico-vaginal fistula
A case of gas gangrene is presented. The patient was a 78-year-old woman who was admitted with the diagnosis of vesico-vaginal fistula. Cystography revealed a vesico-intestinal fistula and leakage of contrast medium into the prevesical space, in addition to the vesico-vaginal fistula. Right ureterostomy was performed. Two weeks postoperatively, she complained of severe pain and swelling of her right thigh. The swelling grew rapidly and general condition became worse. A diagnosis of gas gangrene was made 8 days after her first complaint by demonstrating subcutaneous and intramuscular gas formation in X-ray. She died the next day. By the bacteriological examination, this case was non-clostridial gas gangrene
Short- and long-term outcome after urethroplasty in the patients with hypospadias treated by Hodgson III method
Hodgson III法一期的尿道形成術29症例を臨床的に検討した.初回成功率は62.1%で, おもな短期合併症は, 瘻孔10例, 狭窄3例で, 瘻孔のうち5例は長期においても残存した.長期合併症において, 新たに勃起障害1例が認められたが, 術式に起因する合併症ではないBetween 1977 and 1997, 29 patients with hypospadias were surgically treated by Hodgson type III urethroplasty at Tsukuba University Hospital. The duration of surgery ranged from 150 to 535 minutes with an average of 269.3 minutes and the urethral catheter was removed between 4 and 14 days (average 8.7 day) after surgery. The postoperative hospital stay ranged from 10 to 29 days with an average of 18.4 days. The overall success rate of initial surgery was observed in 18 of the 29 patients (62.1%). As early postoperative complications, urethral fistula and stricture were seen in 10 (34%) and 3 (10%) patients, respectively; of these four fistulas persisted. As late complications revealed by questionnaire, erectile disorder was observed in one case. To obtain a higher success rate on initial treatment, skillful surgical technique and selection of appropriate cases are required
A case of malignant paraganglioma within the renal sinus
A case of malignant paraganglioma within the renal sinus is presented. A 51-year-old woman underwent left transabdominal nephrectomy for renal tumor. Pathologically, the tumor was malignant nonchromaffin paraganglioma. This tumor seemed to originate from parasympathetic paraganglions around the left renal artery. Paraganglioma is rare in the literature. Especially, this may be the first report of such a lesion in the renal sinus
A case of Kallmann syndrome: usefulness of the aging male's symptoms rating scale for assessment of subjective symptoms
30歳男.第2次性徴の遅延, ED, 嗅覚低下を自覚し, 性腺機能低下症との類似を知り, 外陰部の増大および勃起機能の改善を希望した.頭部MRIにて両側嗅裂, 下垂体の形態に異常は認められず.内分泌学的検査およびホルモン負荷試験よりKallmann症候群と診断した.hCG5000単位およびhMG150単位を週2回の治療を開始し, 直後より勃起力の改善を自覚し, 12ヵ月後の時点で血中テストステロン, 遊離テストステロンは正常化し, LH, FSHは若干その増加を示し, PRLは正常範囲を推移した.陰茎長, 精巣容積も増加し, 陰毛も発達し精液検査でも改善されIIEF5は23点で, AMS総スコアは39点から20点となったWe report a case of Kallmann syndrome in which the aging male's symptoms rating scale (AMS) was useful for assessment of subjective symptoms. A 30-year-old male was admitted to Tsukuba University Hospital with a complaint of delayed puberty in May 2003. He presented with hypogonadism, gynecomastia and anosmia. The plasma levels of luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone were very low. However, the LH-releasing hormone test and human chorionic gonadotropin (hCG) loading test identified normal function of pituitary and Leydig cell. After 12 months of treatment with hCG and human menopausal gonadotropin (hMG), the amount of pubic hair and the volume of testes had increased as well as the level of serum testosterone. The total score of AMS after treatment has been improved from 39 to 20 as compared with that before treatment
A case of retroperitoneal liposarcoma
A 77 year-old woman presented with the chief complaint of a mass in the right upper quadrant. The examination on admission including IVP, echography, Ga scintigraphy, barium enema, CT scan, and angiography revealed that the right kidney and ascending colon were displaced by the mass. Under the diagnosis of retroperitoneal tumor, operation was carried out. Most of the mass was resected with the right kidney. The pathological diagnosis of the resected tumor revealed well differentiated liposarcoma. Convalescence was uneventful and the patient has been well and free from disease for 14 months. Based on our experience and the review of the pertinent literature in English and Japanese, we emphasize the importance of definite surgery and close follow up, as liposarcoma is frequently recurrent
A case of transitional cell carcinoma of the urinary bladder with high serum level of CEA and CA19-9
85歳男.血清CEA, CA19-9が高値を示した浸潤性膀胱腫瘍(移行上皮癌)であった.いずれの腫瘍マーカーも組織内での発現が確認され, 治療に伴う腫瘍サイズの減少と共に血清値の低下を認めた.治療開始後CEA, CA19-9は両方ともに腫瘍縮小にしたがい減少したが, その後CA19-9のみ上昇を認めた.原因としては, 1)画像では指摘できないサイズの再発, 転移が生じた, 2)水腎症の増悪によるCA19-9の上昇を生じた, 3)膀胱癌以外の悪性腫瘍の発生, などが考えられる.CA19-9の腫瘍組織内発現が確認されていることより, 1が最も考えられたが, CT等の画像や尿細胞診では病変の存在は指摘できなかった.腫瘍マーカー産生移行上皮癌において, これらの腫瘍マーカーが治療効果判定に有用であることが示されたAn 85-year-old male with asymptomatic gross hematuria was diagnosed with invasive bladder tumor, transitional cell carcinoma grade 3. Serum levels of CEA and CA19-9 were elevated and histological examination revealed expression of both markers in the cytoplasm of cancer cells. Out of therapeutic options, intra-arterial chemotherapy and radiotherapy were selected because of his age. During the treatment, serum levels of CEA and CA19-9 decreased along with reduction of tumor size. These serum markers have been reported to be elevated in 10 to 60% of patients with bladder tumor and are useful markers for evaluation of the treatment as suggested in the present case
Saphenous vein grafting for Peyronie's disease: a case report
50歳男.陰茎背部に米粒大有痛性結節を自覚し, 以後, 進行を認めた.陰茎の屈曲を主訴に受診した.臨床的にPeyronie病と診断した.精査, 治療目的で入院した.臨床症状及び画像所見からPeyronie病と診断し, 勃起時の屈曲度が強く, 保存的療法では緩解が困難と考え, 全身麻酔下に陰茎海綿体白膜の硬結切除, 大伏在静脈による欠損部のパッチ形成術を施行した.約6ヵ月後の現在外来で経過観察中である.勃起能は受診時と比して同様に認められている.勃起時の屈曲はほぼ改善したが, 切除部の更に近位側に硬結の再発がみられ, 勃起時に陰茎全体が背側に軽度彎曲する状態である.疼痛は通常及び勃起時にも認めていないWe present a case of Peyronie's disease in a 50-year-old male with a progressive, painful induration (3 x 2 x 0.5 cm) in the dorsal region of the penis. In order to correct the high degree of penile curvature, we made a venous patch graft from the saphenous vein under general anesthesia and straightened the penis. Six months after the operation, a recurrent induration was observed in the proximal region of the penis, and the penis became slightly shortened
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