24,418 research outputs found
Comparison of drinking water supply in the municipality of Črenšovci before and after joining a singel system
V diplomskem delu je predstavljena oskrba s pitno vodo na območju Občine Črenšovci. Prvi del opisuje trenutno in predhodno stanje oskrbe s pitno vodo na celotnem območju. Predstavljeni so prejšnji sistemi oskrbe po naseljih in novozgrajen enovit sistem »Oskrba s pitno vodo Pomurja – sistem A«, ki vključuje območje Občine Črenšovci. V drugem delu so prikazani rezultati analiz pitne vode na vseh omenjenih sistemih. Na podlagi prikazanih rezultatov je narejena primerjava kakovosti pitne vode med prejšnjim in trenutnim sistemom oskrbe. Po opravljeni primerjavi prikazanih rezultatov ugotavljamo, da je z izgradnjo novega enovitega sistema, kakovost pitne vode na celotnem območju občine izboljšana. Predvsem v naseljih Trnje in Žižki je opaziti občutno izboljšanje rezultatov kemijske analize.The diploma thesis presents the drinking water supply within the area of the Municipality of Črenšovci. The first part describes current and previous state of drinking water supply in that entire area. It also shows the previous settlement supply systems and the newly built single plumbing system "Pomurje region drinking water supply – A system”, which includes the area of the Municipality of Črenšovci. The second part contains results of the analysis of drinking water within all of these systems. Based on the results presented, we have made a comparison of the quality of drinking water in the previous and the current supply system. In accordance with this comparison, we have made a conclusion that the drinking water quality has improved in the entire municipality area. The biggest improvement can be seen in the chemical analysis results of the Trnje and Žižki settlements
Tompa M: Statistics of local multiple alignments
Summary: BLAST statistics have been shown to be extremely useful for searching for significant similarity hits, for amino acid and nucleotide sequences. Although these statistics are well understood for pairwise comparisons, there has been little success developing statistical scores for multiple alignments. In particular, there is no score for multiple alignment that is well founded and treated as a standard. We extend the BLAST theory to multiple alignments. Following some simple assumptions, we present and justify a significance score for multiple segments of a local multiple alignment. We demonstrate its usefulness in distinguishing high and moderate quality multiple alignments from low quality ones, with supporting experiments on orthologous vertebrate promoter sequences. Contact
Analysis of computational approaches for motif discovery
Abstract Recently, we performed an assessment of 13 popular computational tools for discovery of transcription factor binding sites (M. Tompa, N. Li, et al., "Assessing Computational Tools for the Discovery of Transcription Factor Binding Sites", Nature Biotechnology, Jan. 2005). This paper contains follow-up analysis of the assessment results, and raises and discusses some important issues concerning the state of the art in motif discovery methods: 1. We categorize the objective functions used by existing tools, and design experiments to evaluate whether any of these objective functions is the right one to optimize. 2. We examine various features of the data sets that were used in the assessment, such as sequence length and motif degeneracy, and identify which features make data sets hard for current motif discovery tools. 3. We identify an important feature that has not yet been used by existing tools and propose a new objective function that incorporates this feature.</p
Recommended from our members
'Taint not thy mind'
ABSTRACT OF THE THESIS`Taint not thy mind' in HamletbyMichael Socrates MoranMaster of Fine Arts in Theatre and Dance (Directing)University of California, San Diego, 2015Professor Gabor Tompa, ChairThe play Hamlet is a trap of mirrors for both its characters and the artists that produce it. Like Hamlet, working on this play felt like the inevitable 'walking into one's grave' and thereupon begin suffering the abject terror of unknown consequences. It is a trap of mirrors because it reflects back our unpleasant and inescapable darkness. It transfixes the imagination to observe the anguish the noble prince Hamlet endures. He who wishes to illuminate the world must navigate his dark side and the dark side of others.I directed Hamlet because I wanted to understand the transformation of Hamlet in the fifth act. I lived in terror of producing this play. However, I developed at least a modest awareness of the inevitable limitations that adhere to its production. The play is either too introspective or too extroverted. The wrongdoings are either minor or profligate. Also, some of the shortcomings and wrongdoings are not susceptible to change. The awareness of our failings transforms our relationship with the world. Is it possible that the trap of mirrors ceases to affect us so violently once we see the darkness the mirrors reveal about ourselves?At the end of the day, a proverb by the monk, Martin Luther, seems applicable to Hamlet's journey, to the play's history and to all the collaborators who worked so diligently: `Sin bravely'. If the root meaning of the word `sin' is to miss the mark, then perhaps we `sin bravely' because it is only by missing the mark, by walking into the unknown and by facing our terror, that we might be saved
Jack Alive / Martin Dead : The Location of the "Author" in Jack London\u27s Martin Eden
This essay is an attempt to read Martin Eden, Jack Londonʼs autobiographical novel, in terms of the inextricable relationship between the author and the protagonist. Critics have often taken the unbalanced plot and the lack of ironic distance between narrator and character in Martin Eden as the technical weakness of London, but this paper argues that the achievement of this novel owes a great deal to the attachment of London to Martin. The unbalanced structure is a necessary product of the severe struggle of the author to kill his romantic alter ego. // Martin, who aspires to win Ruth Morse, tries to cross class boundaries by making a career of a writer. Even after realizing the emptiness of Ruth, who turns out to be nothing but a typical figure of the bourgeoisie, he somehow persists in loving her. The notion underlying here is that, for Martin, love, career and art are fundamentally inseparable. He objects to the aestheteʼs view of Brissenden on account of his separation of art from career. Martinʼs identity and life consist only in the triunity of love/career/art; the alternative is the repudiation of life. Thus, the unnatural delay of his disappointment in love can be regarded as Londonʼs strategy to set the suicide of Martin as the necessary consequence of the story. // By finishing the story and killing Martin, London finally detaches himself from Martin, reconstructs his self, and, unlike Martin, survives as a professional writer. In this sense, Martin Eden is a story about “writerʼs self-reconstruction.
Recommended from our members
Letter from Martin Chizzick
Congratulations to Duane Pearsall for receiving the Enterpreneur of the Year award; note on the letter was written by Pearsall and it mentions that Martin, the author of the letter, died in a airplane accident
Robert Martin Tiffin's Mystery Man Newspaper Articles
Advertiser-Tribune newspaper clippings featuring a story about Robert Martin (written by Nancy Kleinhenz), a local author from Tiffin (Ohio) who wrote under the pseudonym of Lee Roberts, and two of his short stories. Martin wrote mystery novels in his spare time, creating more than 22 mystery novels. For more information about Robert Martin and a list of books go to http://www.mysteryfile.com/RMartin/JBennett.html
∗ corresponding author
The DNA motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif discovery that motivates the following algorithmic challenge: find twenty planted occurrences of a motif of length fifteen in roughly twelve kilobases of genomic sequence, where each occurrence of the motif differs from its consensus in four randomly chosen positions. Such “subtle ” motifs, though statistically highly significant, expose a weakness in existing motif finding algorithms, which typically fail to discover them. Pevzner and Sze introduced new algorithms to solve their (15,4)-motif challenge, but these methods do not scale efficiently to more difficult problems in the same family, such as the (14,4)-, (16,5)-, and (18,6)-motif problems. We introduce a novel motif discovery algorithm, Projection, designed to enhance the perfor-mance of existing motif finders using random projections of the input’s substrings. Experiments on synthetic data demonstrate that Projection remedies the weakness observed in existing algo-rithms, typically solving the difficult (14,4)-, (16,5)-, and (18,6)-motif problems. Our algorithm is robust to nonuniform background sequence distributions and scales to larger amounts of sequence than that specified in the original challenge. A probabilistic estimate suggests that related motif-finding problems that Projection fails to solve are in all likelihood inherently intractable. We also test the performance of our algorithm on realistic biological examples, including transcription factor binding sites in eukaryotes and ribosome binding sites in prokaryotes. 1
Experiences Using Large Scale Video Walls for Distance Education
We describe our experiences building and using the Rutgers Videowall, a low-cost telepresence system that has been used teaching 15 courses and colloquia. By relaxing typical spatial telepresence features, such as background continuity, we greatly reduced costs and gained flexibility in the rooms it could be deployed in. The lower costs and room flexibility enabled academic departments to use the wall, in contrast to traditional telepresence systems which remained inaccessible. We found that the Videowall’s spatial distortions did not have a significant impact on useability, as our initial survey results show that students had an overall positive experience.Technical report DCS-tr-72
Hans Martin Schwarz Collection 1934 - 1938
This collection contains clippings of articles by Hans Martin Schwarz (1917, Hamburg – 2006, New York, better known as Martin Ebon), published between 1934 and 1938 in German-Jewish newspapers on a wide variety of subjects such as sports, emigration, the political situation in Germany, and religious attitudes of the young. It also contains reviews of his books "Einer wie Du und Ich" and "Heiteres, Besinnliches, Nachdenkliches."digitizedHans Martin Schwarz (1917, Hamburg – 2006, New York, better known as Martin Ebon), was a journalist and author. In Germany during the 1930s, he published in a variety of German-Jewish periodicals, primarily the Israelitisches Familienblatt. After immigrating to the United States in 1938, he changed his name to Martin Ebon, and published dozens of books in the areas of world affairs and parapsychology.Processe
- …
