1,141 research outputs found
Supplemental Material - The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies
No full textSupplemental Material for The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies by Adolfo Toledano-Díaz, M Isabel Álvarez and Adolfo Toledano in Journal of Central Nervous System Disease</p
Supplemental Material - The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies
No full textSupplemental Material for The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies by Adolfo Toledano-Díaz, M Isabel Álvarez and Adolfo Toledano in Journal of Central Nervous System Disease</p
Supplemental Material - The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies
No full textSupplemental Material for The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies by Adolfo Toledano-Díaz, M Isabel Álvarez and Adolfo Toledano in Journal of Central Nervous System Disease</p
Supplemental Material - The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies
No full textSupplemental Material for The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies by Adolfo Toledano-Díaz, M Isabel Álvarez and Adolfo Toledano in Journal of Central Nervous System Disease</p
Supplemental Material - The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and the related controversies II: <b>gliotherapies and multimodal therapy</b>
No full textSupplemental Material for The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and the related controversies II: gliotherapies and multimodal therapy by Adolfo Toledano-Díaz, M Isabel Álvarez and Adolfo Toledano in Journal of Central Nervous System Disease</p
Supplemental Material - The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies
No full textSupplemental Material for The relationships between neuroglial and neuronal changes in Alzheimer’s disease, and related controversies by Adolfo Toledano-Díaz, M Isabel Álvarez and Adolfo Toledano in Journal of Central Nervous System Disease</p
Brain local and regional neuroglial alterations in Alzheimer´s disease Cell types, responses and implications
No full textFrom birth to death, neurons are dynamically accompanied by neuroglial cells in a very close morphological and functional relationship. Three families have been classically considered within the CNS astroglia, oligodendroglia and microglia. Many types/subtypes (including NGR2+ cells), with a wide variety of physiological and pathological effects on neurons, have been described using morphological and immunocytochemical criteria. Glio-glial, glio-neuronal and neuro-glial cell signaling and gliotransmission are phenomena that are essential to support brain functions. Morphofunctional changes resulting from the plasticity of all the glial cell types parallel the plastic neuronal changes that optimize the functionality of neuronal circuits. Moreover, neuroglia possesses the ability to adopt a reactive status (gliosis) in which, generally, new functions arise to improve and restore if needed the neural functionality. All these features make neuroglial cells elements of paramount importance when attempting to explain any physiological or pathological processes in the CNS, because they are involved in both, neuroprotection/neurorepair and neurodegeneration. There exist diverse and profound, regional and local, neuroglial changes in all involutive processes (physiological and pathological aging; neurodegenerative disorders, including Alzheimer´s disease –AD-), but today, the exact meaning of such modifications (the modifications of the different neuroglial types, in time and place), is not well understood. In this review we consider the different neuroglial cells and their responses in order to understand the possible role they fulfill in pathogenesis, diagnosis and treatment (preventive or palliative) of AD. The existence of differentiated and/or concurrent pathogenic and neuro-protective/neuro-restorative astroglial and microglial responses is highlighted. © 2016 Bentham Science Publishers
LUCHAS DE PODER EN LA MÉRIDA VISIGODA
Get PDFEn este estudio nos proponemos analizar las relaciones consabidas entre los obispos católicos y arrianos de Emerita Augusta (Mérida, España) respecto a la capital del reino localizada en Toledo. De este modo analizaremos en un primer momento las tensiones entre Masona y Leovigildo y, en un segundo momento, estudiaremos la revuelta de Sunna y Segga contra el rey toledano Recaredo. Todo ello nos servirá para ver que, ambos enfrentamientos, hay que ubicarlos más como uno de los típicos enfrentamientos entre grupos aristocráticos visigodos en pos de la búsqueda o conservación del poder que a luchas de religión (arrianismo-catolicismo)
El elemento acuático en las Rimas de Gustavo Adolfo Bécquer
Get PDFAn aquatic element in the Rhymes by Gustavo Adolfo BécquerThe author of this article analyses the poetry of Gustavo Adolfo Bécquer, gathered in the collection of the Rhymes, from a perspective of its symbolism. She concentrates mainly on the aquatic symbols as an illustration of the womanhood, human desires, inspiration, unconsciousness and death.An aquatic element in the Rhymes by Gustavo Adolfo BécquerThe author of this article analyses the poetry of Gustavo Adolfo Bécquer, gathered in the collection of the Rhymes, from a perspective of its symbolism. She concentrates mainly on the aquatic symbols as an illustration of the womanhood, human desires, inspiration, unconsciousness and death
Del "Vespasiano" que editó Bonilla y San Martín en 1908, o Del hallazgo de un raro y curioso post-incunable toledano
Get PDFEn esta nota se ofrece la noticia del hallazgo del primer ejemplar conocido de la edición de La Destruicion de Jerusalem, en que se ofreció la Estoria del noble Vespasiano, cuyo texto editó Adolfo Bonilla y San Martín en 1908, sin ninguna información sobre la impresión ni sobre el ejemplar utilizado. Se analizan los elementos de interés tipobibliográfico y biblioiconográfico que justifican la atribución de la impresión al taller toledano del Sucesor de Pedro Hagenbach, presumiblemente en 1510
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