94 research outputs found

    ASO Author Reflection: Isolated Limb Infusion for Locally Advanced Melanoma in the Extremely Old Patient is Safe and Effective

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    ASO Author reflectionsAbstract unavailableJüri Teras, Hidde M. Kroon and Jonathan S. Zage

    ASO Author Reflections: Return to Isolated Limb Infusion for In-Transit Melanoma

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    ASO Author ReflectionsMichael J. Carr, Hidde M. Kroon, and Jonathan S. Zage

    ASO Author Reflections: International Experience of Isolated Limb Infusion for Melanoma Shows Durable Response

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    Abstract unavailableJohn T. Miura, Hidde M. Kroon, and Jonathan S. Zage

    MP.2020.2554.Leplaa

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    Bayesian evaluation of replication studies Author(s) Hidde Jelmer Leplaa, Charlotte Rietbergen, Herbert Hoijtink Submission to Meta-Psychology. Contains the full history, including all correspondence, decisions, reviews, revisions etc. Anyone can participate in open peer review directly by using the hypothes.is commenting function on the preprint

    Hello, do you hear me? Debating the poetics and noetics of orature. A comment to Ali Moussa Iye

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    In this article, the author comments on Ali Moussa Iye theory about Somalis relationship with orality and writing.Qoraagu wuxuu maqaalkaan ka faalloonayaa fikraddii Cali Muuse Ciye oo ku saabsan xiriirka ay Soomaalidu la leedahay hidde-afeedka iyo qoraalka.In questo articolo, l'autore commenta la teoria di Ali Mousse Iye relativa al rapporto dei somali con l'oralità e la scrittura.M.S. Lilius (ed.

    Buying with impact: Stimulating sustainable public procurement in the construction sector through collaborative practices

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    Public organisations are shifting their focus towards the implementation of sustainability into their projects through sustainable public procurement, but recent studies indicated that the implementation is still lacking. Sustainable public procurement is only implemented in around 10% of the Dutch public procurement tenders (Yu et al. 2020). One of the reasons for the lack of implementation is the added complexity to the job of the procurement specialist. MVI platform helps these procurement specialists by guiding them through this complex task. During their work they found out that a lot of potential positive impact is lost at the start of a project. The most potential for impact is found in the civil construction sector, due to the size of its projects. Because of this potential, the graduation project is aimed at stimulating sustainable public procurement for civil construction projects. This graduation project focusses on the design of an intervention at the early stages of a project in order to start creating more positive social and environmental impact. This is done through the design of practices that support a pragmatic and collaborative approach. During these practices, a mix of vision, management and execution stakeholders come together to share ideas, discuss and prioritize in order to decide which role sustainability should play within the project. The community of practice theory and boundary object theory as well as the SDG procurement compass from MVI platform were used to give shape to the practices. During the graduation project, two practices were created in the form of online workshops. The first workshop focussed on the definition of sustainable ambitions within the project. During the second workshop, the participants formulated measurable goals and made a list of actions and key stakeholders. The workshops were tested during multiple case studies, and iterations on the workshops were made based on the received feedback. After iterations, the early stage intervention, also called SDG impact kick-off, is designed to be a set of three workshops. The ambitions -, actions -, and stakeholders workshop. Although it was not possible to measure the actual impact of the workshops on the projects that were used as case studies, the feedback and results from the workshop seemed promising. The workshops clarified how sustainability could be implemented and helped to create a concrete implementation plan. A plan that helps project leaders with integrating sustainability and helps procurement specialist with setting up sustainable public procurement procedures. All in all, these collaborative practices are believed to aid in the creation of more positive sustainable impact in construction projects. The workshops of the SDG impact kick-off form a beginning of a practice that makes sustainability an integral part of any project.https://open.spotify.com/show/6T1w8pZyeKlUX97snPBbjx Spotify link to the podcastStrategic Product Desig

    Assessing the remaining life of the Hollandsche IJssel storm surge barrier

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    The Hollandsche IJssel storm surge barrier is expected to last another 40 years, but replacement or renovation may be needed sooner than anticipated due to factors such as climate change and societal developments. Yet, there is relatively little known about what factors and how these factors influence the remaining life, and methods that can be used to estimate the remaining life of the barrier are lacking. This thesis aims to identify the dominant factors and associated uncertainties affecting the remaining life and to provide a method for the estimation of the remaining life of the Hollandsche IJssel storm surge barrier. The focus of the study is on the functional and technical life of the barrier.First, the functions and structural components of the storm surge barrier were identified. For each function, requirements were formulated to support the evaluation of the impact of the external drivers. The physical decomposition of the storm surge barrier was needed to identify the dominant deterioration mechanisms. This analysis revealed that the technical life is not governing for the total remaining life of the barrier. Therefore, the focus should mainly be on the functional life of the storm surge barrier. Next, the impact of external drivers on the functional performance or technical state of the barrier was evaluated by a semi-quantitative analysis in which scenarios with the projected changes were used. The study identified sea level rise as the dominant (physical) driver affecting the remaining life of the storm surge barrier because of the potentially large future changes and far-reaching consequences. By combining the required performance levels expressed as critical amounts of sea level rise with various sea level rise projections, estimates of the remaining life of the Hollandsche IJssel barrier were obtained. It was found that even for moderate sea level rise scenarios, there is a significant probability that the end of life of the barrier could be reached within 20 years. The estimates of the remaining life of the barrier are, however, uncertain, and a considerably longer lifespan cannot be ruled out. Accordingly, it is recommended to investigate possible measures to lengthen the lifespan and determine the best moment in time to implement these measures. The decision to implement specific measures will be dependent on the costs and benefits. Economic considerations should therefore be included as well. Furthermore, a more system-oriented approach is recommended for this kind of analysis since modifications to a certain object could impact other elements within the system, e.g. dike reinforcements affect the required closure reliability of the storm surge barrier. Finally, a more general recommendation is to perform similar studies for other critical structures as the remaining life of those structures may also be reached sooner than anticipated if, for example, functional aspects are taken into account. Civil Engineering | Hydraulic Engineering | Hydraulic Structures and Flood Ris

    Towards on-time passenger handling: A case study research on the required service capacity for an on-time passenger-handling process at the gate

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    Airline passengers want short and seamless connections, departure and arrival punctuality are therefore key. KLM is currently losing a strong position as network connector, as the operability of transfer flights is under pressure: departure punctuality is substandard. Offering attractive connections to passengers is KLM’s right of existence as 70% of its customers are transferring at their only hub: Amsterdam Airport Schiphol. Therefore, the departure punctuality should be brought back to an acceptable level. KLM scores well on the international standard indicator for arrival punctuality, their on-time departure punctuality is however substandard: declining from 50% in 2009 to as low as 20% over 2014. One contributor to the low departure performance is the inefficient ground operation. Regarding the passenger-handling process there were some other figures raising questions. In 53% of the cases the gate process took longer than planned. The gate process is therefore the object of study.Mechanical, Maritime and Materials EngineeringMarine and Transport TechnologyTransport Engineering and Logistics2015.TIL.793

    Connecting the dots, high field ballistic supercurrents

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    We study the flow of supercurrents between two superconducting contacts connected by a 2d layer of graphene. We use a Markov chain Monte Carlo method to find Andreev bound states for circular electron trajectories. Using sample trajectories we estimate the currents as function of the superconducting phase difference between the contacts and the magnetic field.<br/
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