92 research outputs found

    Oriki Ogun (Praise of the God of Iron) by Mayowa Adeyemo

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    Lagos State University music student, Mayowa Adeyemo, praises Ogun (Yoruba Orisha/God of Iron). Recorded on July 26, 2013 at Peter King College of Music near Badagry, Lagos State. Keywords: African History; African Languages and Societies; Critical and Cultural Studies; Dance; Digital Humanities; Ethnic Studies; Ethnomusicology; Folklore; Gender, Race, Sexuality, and Ethnicity in Communication; Linguistic Anthropology; Oral History; Performance Studies; Poetry; Race and Ethnicity; Social and Cultural Anthropology; Sociology of Culture

    Open access publishing: A review of publications originating from a medical college in Nigeria

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    Background: Open Access (OA) publishing has gained tremendous acceptance in academic publishing over the last decade. This paper reviews the number and trend of OA publishing of research papers originating from College of Medicine University of Lagos (CMUL), Nigeria. Materials and Methods: A computerized literature search of PubMed for all published articles originating from CMUL between 1976 and 2013 was conducted. The search phrase used was "College of Medicine University of Lagos". The search was conducted on March 30, 2013. All articles tagged "Free article" or "Free PubMed article" were selected. Results: A total of 1255 articles appeared in PubMed between 1976 and 2013 (37 years). At the first level of screening, 162 articles were identified as "Open Access". Second level of screening to eliminate articles not originating from CMUL identified 124 articles. Only 15 OA articles were published between 1976 and 2000 (24 years), 11 articles appeared as "Open Access" journals between 2001 and 2005 (5 years), 44 between 2006 and 2010 (5 years), and 54 articles were published between 2011 and 2013. Twenty-four of these articles were published in Nigerian OA Journals, and the remaining articles (100) in foreign journals. Conclusions: OA publishing is becoming popular among researchers at CMUL. This trend has been observed worldwide. Nigerian researchers are advised that while going along with the worldwide trend, they should however, be aware of predatory OA journals and publishers. The criteria for determining predatory OA publishers can be accessed via: www.scholarlyoa.com/publishers

    An evangelical voice in Africa: the worldview background of the theology of Tokunboh Adeyemo (1 October 1944-17 March 2010)

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    Africa was blessed with a son of the calibre of Dr Tokunboh Adeyemo. Since he only recently passed away, we do not yet have (as far as the author is aware) an assessment of the legacy of this eminent Christian leader. This article is the first preliminary evaluation written from a reformational worldview perspective.   The set-up of the investigation is as follows: Firstly, a brief out- line is given of his life history, especially his training in the Evangelical tradition. Then, the décor (the overall situation of African Christianity) that was the background against which he lived and worked is painted. Thirdly, it is followed by the strengths and weaknesses of Evangelical Christianity of which Adeyemo was a representative. Fourthly, it is indicated how Adeyemo thought in line with post-Lausanne Evangelicalism. In the fifth place a preliminary worldview evaluation of his legacy is given. To assist possible future research a bibliography of his most important publications concludes the investigation

    Time Index: Oriki Ogun (Praise of the God of Iron) by Mayowa Adeyemo

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    This file is the time index for " Oriki Ogun (Praise of the God of Iron) by Mayowa Adeyemo

    Orofacial manifestation of hematological disorders: Hemato-oncologic and immuno-deficiency disorders

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    The aim of this paper is to review the literature and identify orofacial manifestations of hematological diseases with special reference to hemato-oncologic, immuno-deficiency disorders, and human immunodeficiency virus infection. A computerized literature search using MEDLINE was conducted for published articles on orofacial manifestations of hematological diseases with emphasis on hemato-oncologic and human immunodeficiency virus (HIV) infection. Mesh phrases used in the search were: Oral diseases AND hematological disorders; orofacial diseases AND leukemias; orofacial lesions AND lymphomas; orofacial diseases AND multiple myeloma, orofacial manifestations AND HIV. The Boolean operator "AND" was used to combine and narrow the searches. The full texts of these articles were thoroughly examined. References in these articles also were manually searched non-Medline articles. Only relevant articles were selected for the review. Orofacial manifestation of malignant hematological diseases may present as primary clinical features due to infiltration of orofacial tissues, or as secondary due to the subsequent infiltration of normal bone marrow elements, or tertiary due to the side effects of the treatment. HIV-associated orofacial lesion may be a clinical indicator of HIV infection in otherwise healthy, undiagnosed individuals; an early clinical feature of HIV infection; clinical markers for the classification and staging of HIV disease or may be a predictor of HIV disease progression. Orofacial manifestations of malignant hematological diseases and HIV infection are not uncommon findings in clinical practice. These manifestations may be clinical indicators of hematologic disorders in otherwise healthy, undiagnosed individuals

    Orofacial manifestations of hematological disorders: Anemia and hemostatic disorders

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    The aim of this paper is to review the literature and identify orofacial manifestations of hematological diseases, with particular reference to anemias and disorders of hemostasis. A computerized literature search using MEDLINE was conducted for published articles on orofacial manifestations of hematological diseases, with emphasis on anemia. Mesh phrases used in the search were: oral diseases AND anaemia; orofacial diseases AND anaemia; orofacial lesions AND anaemia; orofacial manifestations AND disorders of haemostasis. The Boolean operator "AND" was used to combine and narrow the searches. Anemic disorders associated with orofacial signs and symptoms include iron deficiency anemia, Plummer-Vinson syndrome, megaloblastic anemia, sickle cell anemia, thalassaemia and aplastic anemia. The manifestations include conjunctiva and facial pallor, atrophic glossitis, angular stomatitis, dysphagia, magenta tongue, midfacial overgrowth, osteoclerosis, osteomyelitis and paraesthesia/anesthesia of the mental nerve. Orofacial petechiae, conjunctivae hemorrhage, nose-bleeding, spontaneous and post-traumatic gingival hemorrhage and prolonged post-extraction bleeding are common orofacial manifestations of inherited hemostatic disorders such as von Willebrand′s disease and hemophilia. A wide array of anemic and hemostatic disorders encountered in internal medicine has manifestations in the oral cavity and the facial region. Most of these manifestations are non-specific, but should alert the hematologist and the dental surgeon to the possibilities of a concurrent disease of hemopoiesis or hemostasis or a latent one that may subsequently manifest itself

    Frequency of homologous blood transfusion in patients undergoing cleft lip and palate surgery

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    Aim: The study aims to determine the frequency of homologous blood transfusion in patientsundergoing cleft lip and palate surgery at the Lagos University Teaching Hospital, Nigeria. Setting and Design: A prospective study of transfusion rate in cleft surgery conducted at the Lagos University Teaching Hospital, Nigeria. Material and Methods: One hundred consecutive patients who required cleft lip and palate surgery were recruited into the study. Data collected included age, sex and weight of patients, type of cleft defects, type of surgery done, preoperative haematocrit, duration of surgery, amount of blood loss during surgery, the number of units of blood cross-matched and those used. Each patient was made to donate a unit of homologous blood prior to surgery. Results: There were 52 females and 48 males with a mean age of 64.4 ± 101.1 months (range, 3-420 months). The most common cleft defect was isolated cleft palate (45%) followed by unilateral cleft lip (28%). Cleft palate repair was the most common procedure (45%) followed by unilateral cleft lip repair (41%). The mean estimated blood loss was 95.8 ± 144.9 ml (range, 2-800ml). Ten (10%) patients (CL=2; CP=5, BCL=1; CLP=2) were transfused but only two of these were deemed appropriate based on percentage blood volume loss. The mean blood transfused was 131.5 ± 135.4ml (range, 35-500ml). Six (60%) of those transfused had a preoperative PCV of < 30%. Only 4.9% of patients who had unilateral cleft lip surgery were transfused as compared with 50% for CLP surgery, 11% for CP surgery, and 10% for bilateral cleft lip surgery. Conclusions: The frequency of blood transfusion in cleft lip and palate surgery was 10% with a cross-match: transfusion ratio of 10 and transfusion index of 0.1. A "type and screen" policy is advocated for cleft lip and palate surgery

    The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study

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    Corrected by Erratum: Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study, in PLoS Genetics,12(6):e1006166. The arcOGEN Consortium should be listed as an author of this article.Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age- and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to ~2.8M SNPs with BMI and WHRadjBMI in four strata (men ≤50y, men >50y, women ≤50y, women >50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR<5%) age-specific effects, of which 11 had larger effects in younger (<50y) than in older adults (≥50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may provide further insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.Thomas W. Winkler ... Lyle J Palmer ... CHARGE Consortium, DIAGRAM Consortium, GLGC Consortium, Global-BPGen Consortium, ICBP Consortium, MAGIC Consortium ... et al

    A study on the physical and mechanical properties of a granite outcrop for a quarry at Onikoko community, Oyo State, South-Western Nigeria

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    Purpose. To investigate the physical and mechanical properties of a granite outcrop for a quarry at Onikoko community in Oyo State, South-Western Nigeria. Methods. Samples of granite rock were collected from the outcrop for the laboratory determination of their physical and mechanical properties required for determining its suitability for construction and engineering purposes, and the desired properties were determined. Findings. Results from the tests conducted on the granite samples indicated the various values of physical and mechanical properties of the outcrop in the study area. The results obtained are found to be within the acceptable international standards. Hence, the granite outcrop is found to be suitable for establishing a quarry in the study area based on the results obtained. Originality. The results in this study have affirmed the fact that granite rocks must possess adequate physical and mechanical characteristics to make them suitable for construction and engineering purposes. The physico-mechanical properties of the granite outcrop evaluated in this study having their values within the international standards attest to high strength characterization of the granite rock. The life span of the proposed quarry is established to be forty years, which is also an indication of rich mineralization of the area. Practical implications. Results of this study can be a useful source of information to potential investors and policy makers for the establishment of a quarry in the study area. Hence, government’s attention can be drawn to the needs of the host community for the provision of basic infrastructures.Мета. Дослідити фізичні та механічні властивості відслонених гранітних порід в кар’єрі Онікоко, штат Ойо, Південно-Східна Нігерія. Методика. Зразки гранітної породи були взяті з відслонення для лабораторного визначення їх фізико-механічних властивостей відповідно до Американського стандарту для випробувань матеріалів (ASTM) D 2487 та Міжнародного товариства механіків гірських порід (ISRM). Оцінка запасів гранітного відслонення включала геологічні та геофізичні дослідження, які містили геоелектричні дослідження, в основному із застосуванням методу електричного опору з використанням конфігурації вертикального електричного зондування Шлюмберже (VES) за допомогою вимірювача опору. Результати. Встановлено, що фізико-механічні властивості гранітних зразків відповідають міжнародним стандартам. Виявлено, що відслонення граніту в районі дослідження являє собою залягаюче масивне родовище, яке охоплює великі площі землі, що вказує на те, що відслонення є технічно і комерційно придатним для видобутку корисних копалин з меншим впливом на навколишнє середовище. Проведено оцінку мінеральних запасів родовища, яка дозволила визначити передбачуваний термін експлуатації гранітного кар’єру – 40 років, що підтверджує наявність значних покладів граніту в цьому районі та свідчить про перспективність кар’єрної розробки. Наукова новизна. Встановлено показники фізичних і механічних характеристик гранітів кар’єра Онікоко, де найбільш важливе значення мають їх високі міцнісні характеристики, що доводить їх придатність для використання в будівництві й промисловості. Практична значимість. Результати даного дослідження представляють інтерес для потенційних інвесторів і підприємців, які планують вести кар’єрну розробку граніту в Онікоко, що також приверне увагу уряду до потреб місцевого населення для створення базової інфраструктури.Цель. Исследовать физические и механические свойства обнаженных гранитных пород в карьере Оникоко, штат Ойо, Юго-Восточная Нигерия. Методика. Образцы гранитной породы были взяты из обнажения для лабораторного определения их физико-механических свойств в соответствии с Американским стандартом для испытаний материалов (ASTM) D 2487 и Международным обществом механиков горных пород (ISRM). Оценка запасов гранитного обнажения включала геологические и геофизические исследования, которые содержат геоэлектрические исследования, в основном с применением метода электрического сопротивления с использованием конфигурации вертикального электрического зондирования Шлюмберже (VES) с помощью измерителя сопротивления. Результаты. Установлено, что физико-механические свойства гранитных образцов соответствуют международным стандартам. Выявлено, что обнажение гранита в районе исследования представляет собой залегающее массивное месторождение, охватывающее большие площади земли, что указывает на то, что обнажение является технически и коммерчески пригодным для добычи полезных ископаемых с меньшим воздействием на окружающую среду. Проведена оценка минеральных запасов месторождения, которая позволила определить предполагаемый срок эксплуатации гранитного карьера – 40 лет, что подтверждает наличие обширной залежи гранита в этом районе и свидетельствует о перспективности карьерной разработки. Научная новизна. Установлены показатели физических и механических характеристик гранитов карьера Оникоко, где наиболее важное значение имеют их высокие прочностные характеристики, что доказывает их пригодность для использования в строительстве и промышленности. Практическая значимость. Результаты данного исследования представляют интерес для потенциальных инвесторов и предпринимателей, которые будут вести карьерную разработку гранита в Оникоко, что также привлечет внимание правительства к нуждам местного населения для создания базовой инфраструктуры.This research was funded by Geocardinal Engineering Services Limited, Abuja, Nigeria. The authors express deep appreciation to the management of the company. The site personnel of the company are equally appreciated for their support during the field work

    Iron stores in regular blood donors in Lagos, Nigeria

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    Adewumi Adediran,1 Ebele I Uche,2 Titilope A Adeyemo,1 Dapus O Damulak,3 Akinsegun A Akinbami,4 Alani S Akanmu1 1Department of Hematology and Blood Transfusion, University of Lagos, Lagos, Nigeria; 2Department of Hematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos, Nigeria; 3Department of Hematology and Blood Transfusion, Jos University Teaching Hospital, Jos, Nigeria; 4Department of Hematology and Blood Transfusion, Lagos State University, Ikeja, Nigeria Background: Apart from challenging the bone marrow to increase its red cell production, thereby producing more blood for the donor, regular blood donation has been shown to have several benefits, one of which is preventing accumulation of body iron which can cause free radical formation in the body. This study was carried out to assess body iron stores in regular blood donors. Methods: A total of 52 regular (study) and 30 first-time (control) volunteer blood donors were studied prospectively. Twenty milliliters of venous blood was drawn from each subject, 5 mL of which was put into sodium ethylenediamine tetra-acetic acid specimen bottles for a full blood count, including red blood cell indices. The remaining sample was allowed to clot in a plain container, and the serum was then retrieved for serum ferritin, serum iron, and serum transferrin receptor measurement by enzyme-linked immunosorbent assay. Results: Mean hemoglobin and packed cell volume in the study group (13.47 &plusmn; 2.36 g/dL and 42.00 &plusmn; 7.10, respectively, P = 0.303) were not significantly higher than in the control group (12.98 &plusmn; 1.30 g/dL and 39.76 &plusmn; 4.41, respectively, P = 0.119). Mean serum ferritin was 102.46 &plusmn; 80.26 ng/mL in the control group and 41.46 &plusmn; 40.33 ng/mL in the study group (P = 0.001). Mean serum ferritin for women in the study group (28.02 &plusmn; 25.00 ng/mL) was significantly lower than for women in the control group (56.35 &plusmn; 34.03 ng/mL, P = 0.014). Similarly, men in the study group had a lower mean serum ferritin (48.57 &plusmn; 45.17 ng/mL) than men in the control group (145.49 &plusmn; 87.74 ng/mL, P = 0.00). The mean serum transferrin receptor value was higher in the study group (1.56 &plusmn; 0.88 &micro;g/mL) than in the control group (1.19 &plusmn; 0.38 &micro;g/mL, P = 0.033). Conclusion: These findings suggest that hemoglobin concentration, packed cell volume, and serum iron levels are not significantly affected by regular blood donation and that regular blood donors appear to have reduced iron stores compared with controls. Keywords: blood donors, hemoglobin, serum ferritin, serum iron, transferrin receptor
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