1,721,028 research outputs found
Bartonella henselae mitral valve endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia in a cat
Full text linkFeline infective endocarditis is a difficult condition to detect and diagnose early, with a
poor long-term prognosis. This case report describes the clinical, laboratory, instrumen-
tal and histological findings in a 12-year-old cat with Bartonella henselae endocarditis
associated with multi-resistant Enterococcus faecalis bacteraemia. The latter pathogen
recently emerged as deadly nosocomial bacteria in humans and is considered a com-
mon cause of infective endocarditis. The prolonged corticosteroid therapy administered
in the cat probably played a role in the onset of B. henselae endocarditis and E. fae-
calis intestinal translocation and bacteraemia. Echocardiography remains the tool of
choice to suspect infective endocarditis, as it can detect vegetative lesions consistent with
this condition. Feline infective endocarditis should always be considered as a differen-
tial diagnosis in cats, especially when there are signs of systemic disease, a history of
prolonged corticosteroid treatment or concomitant infections
Systemic fatal type coronavirus infection in a dog: pathological findings and immunohistochemistry
No full textA case of fatal systemic coronavirus infection is described in a 53-day-old Pekinese dog. Pathological findings and immunohistochemical identification using a monoclonal anti-canine Coronavirus antibody are included. Visceral lesions consisted of extensive fibrinopurulent bronchopneumonia, multiple renal cortical infarcts, severe coalescing centrilobular hepatic fatty change with minimal random hepatic necrosis, and multifocal splenic haemorrhage with lymphoid depletion. Moderate chronic diffuse enteritis was associated with intraluminal adult ascarids. Identification of type I and type 11 coronavirus in this subject had been previously confirmed by genotype-specific real-time reverse transcription-polymerase chain reaction (RT-PCR) assays of the intestinal contents, while only Coronavirus type 11 was detected in visceral organs. This case represents the first description of morphological lesions associated with a type 11 pantropic fatal coronavirus infection in the dog. (c) 2007 Elsevier Ltd. All rights reserved
Anatomo-pathological consequences of Mycotoxins contamination in rabbits feed
No full textMycotoxins are secondary metabolities produced by certain filamentous microscopic fungi, which occur naturally in the environment and may persist in animal feed. In addition to the pathological effects associated with gross and histological changes, a mycotoxin contaminated diet may lead to feed refusal, poor feed conversion and diminished body weight gain which are responsible for great economical losses.The present review summarizes the pathological lesions caused by the most widespread mycotoxins, aflatoxins and ochratoxin, potentially hazardous ingredients of rabbit feed
Vascular Endothelial Growth factor nell’attività angiogenetica dei mastocitomi canini (VEGF)
No full textAN ENZYME-LINKED IMMUNOSORBENT ASSAY FOR THE DETECTION OF ANTIBODIES TO CANINE CORONAVIRUS (CCV)
No full textMultilineage Differentiation Potential of CNS Cell Progenitors in a Recent Developed Gilthead Seabream (Sparus aurata L.) Nervous Model.
Full text linkNeural Progenitor Cells (NPCs) have gathered more and more attention in the field of Neural Stem Cells (NSCs).
However, the multilineage differentiating behavior of these cells and their contribution to tissue regeneration, almost in
lower vertebrate taxa, remain unknown. Since the early 1970s, many comparative studies have been performed using
immunocytochemical screening on the brains of several vertebrate taxa, including teleosts, in order to identify these
cells, even if the data are sometimes contrasting. This study aims: (1) to investigate in vitro the potential proliferative
role of NPCs and Radial Glia Progenitors (RGP) in seabream neurogenesis; (2) to reveal the strict ability of fish NSCs to
undertake the multilineage development and differentiation in neurons, astrocytes and oligodendrocytes.
By the use of double Immunofluorescence (IF) analysis and phase contrast microscopy, we identified the multilineage
differentiation and the exact cell morphology. We demonstrated that NSC can self-renew and differentiate into different
types of neurons or glial cells during extended culturing. Mature neurons expressed specific neuronal markers; they
could differentiate during long term culturing, generating an extensive neurite growth. Glia was found highly mitotic and
could developed mature astrocytes and oligodendrocytes. Glial cells were assessed by Glial Fibrillary Acidic Protein
(GFAP) reactivity; neurons and myelinating oligodendrocytes were immunostained with cell-specific markers.
This work provide that the multilineage differentiation potential of seabream neural cell progenitors might be a useful
tool for neurodegenerative diseases, being a promising approach for repairing the CNS injuries, also in other animals,
as a new coming strategy for function recovery of damaged nerves
- …
