3,955 research outputs found
High-density mapping of left atrial endocardial activation during sinus rhythm and coronary sinus pacing in patients with paroxysmal atrial fibrillation
No full textIntroduction: This study was designed to record global high-density maps of left atrial endocardial activation during sinus rhythm and coronary sinus pacing.Method and Results: Noncontact mapping of the left atrium was performed in nine patients with paroxysmal atrial fibrillation undergoing pulmonary vein ablation procedures. High-density isopotential and isochronal activation maps were superimposed on three-dimensional reconstructions of left atrial geometry. Mapping was repeated during pacing from sites within the coronary sinus. Earliest left atrial endocardial activation occurred anterior to the right pulmonary veins in seven patients and on the anterosuperior septum in two patients. A line of conduction block was seen in the posterior wall and inferior septum in all patients. The direction of activation in the left atrial myocardium overlying the coronary sinus was different from the electrogram sequence in the coronary sinus catheter in 6 of 9 patients. During coronary sinus pacing, activation entered the left atrium a mean (SD) of 41 (13) ms after the pacing stimulus at a site 12 (10) mm from the endocardium overlying the pacing electrode. Lines of conduction block were present in the posterior wall and inferior septum.Conclusion: In patients with paroxysmal atrial fibrillation, lines of conduction block are present in the left atrium during sinus rhythm and coronary sinus pacing. Electrograms recorded in the coronary sinus infrequently correspond to the direction of activation in the overlying left atrial myocardium
A socio-rhetorical exegesis of 1 Timothy 2:8-15
No full textIn this thesis two interralted tasks are undertaken. First, this thesis is an attempt to gain mastery of an interpretive methodology, namely, socio-rhetorical analysis. Second, by looking at a crucial text that has major implications for the contemporary church, I have applied this method of analysis to a particularly Scriptural text, namely, 1 Timothy 2:8-15. In this thesis I demonstrate using socio-rhetorical analysis that the discourse contained in 1 Timothy 2:8-15 constitutes baptised patriarchal cultural practices and traditions from the dominant Greco-Roman culture of the first century. I demonstrate, therefore, that the portrayal of women in the text reflects a cultural imperative, and not a theological imperative, that was co-opted from the ""secular"" Greco-Roman culture of the day and transposed, using Scriptural texts as authentication, into the Christian community at Ephesus. Thus the text is simply re-enforcing normative Greco-Roman cultural values upon Christian women and camouflaging it as a Christian norm in order to persuade women to conform to patriarchal cultural standards. Such persuasion, however, is hardly required unless one has already accepted cultural assumptions about the subordination and silencing (objectification) of women in an androcentric hegemonic culture
Radiofrequency ablation of idiopathic ventricular fibrillation guided by noncontact mapping
No full textA 32-year-old man with idiopathic ventricular fibrillation and an implantable cardioverter defibrillator presented during a ventricular fibrillation storm. Frequent monomorphic ventricular ectopics with left bundle branch block morphology were documented, some of which initiated fibrillation. He underwent noncontact mapping of the right ventricle, during which the ventricular ectopics were mapped to a site in the free wall displaying a diastolic potential 80 ms before ectopic QRS onset. Following three radiofrequency energy applications, the ectopics were abolished. After 11-month follow-up, he has experienced no further arrhythmias. Noncontact mapping may identify ablatable triggers of ventricular fibrillation and lead to successful outcomes even when only single ectopics are present
Processed Multi-Channel Seismic Data from the Galicia S Detachment, Northern Atlantic Ocean, acquired during the R/V Marcus G. Langseth expedition MGL1307 (2013)
No full textA cooperative project between the U.S., U.K., Germany, Spain, and Portugal, this 2013 two-ship seismic experiment surveyed the Galicia Bank region off Iberia. F.S. Poseidon tended the OBS instruments while R/V Marcus G. Langseth fired the airguns. The goal was to collect data necessary to study the rifted continental to oceanic crust transition in the Deep Galicia Basin west of Spain. Workstation Loading Information (mgl1307.procInfo.pdf), rms velocity field (mgl1307.PSTM_Rms.segy) and eta parameter for VTI anisotropy (mgl1307.PSTM_Eta.segy) are available as a Related Documents. Funding was provided by the U.S. NSF (grants OCE10-31769, OCE10-30650, and OCE10-31769), the U.K. Natural Environmental Research Council (grants (NE/E016502/1 and NE/E015883/1), and the GEOMAR Helmholtz Centre for Ocean Research.</span
Persistent hyperammonemia in two related Morgan weanlings
No full textPersistent hyperammonemia was diagnosed in 2 Morgan fillies with clinical signs that developed early in the postweaning period. Diagnostic evaluation, including routine serum chemistries, CBC, liver biopsy, hepatic ultrasonography, liver function test, and necropsy findings did not support a toxic, developmental, or infectious cause. Abnormal serum amino acid and urine orotic acid concentrations suggest that the foals may have had an inherited disorders described in humans as hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome. The disorder is thought to be caused by a defective mitochondrial transporter protein, such that ornithine, required for complete urea synthesis, is deficient, thus causing increases in blood ammonia and ornithine concentrations.LR: 20061115; PUBM: Print; JID: 8708660; 0 (Amino Acids); 7006-33-9 (Ornithine); 7664-41-7 (Ammonia); ppublishSource type: Electronic(1
Book Review: “If That Small Sparke Could Yield So Great a Fire”: Morgan Lloyd Malcolm’s Emilia and Eugenie Freed’s A Several Plot
No full textBook Title: A Several PlotBook Author: Eugenie Freed(Johannesburg: Eugenie R. Freed, 2017)Book Title: EmiliaBook Author: Morgan Lloyd Malcolm(London: Oberon, 2018
Modelling Sociality in a BDI Framework
No full textWe present a conceptual model for how the social nature of agents impacts upon their individual mental states. Roles and social relationships provide an abstraction upon which we develop the notion of social mental shaping
On Cooperation in Multi-Agent Systems
No full textShort Communication
On cooperation in multi-agent systems 1
J. E. DORAN a1, S. FRANKLIN a2, N. R. JENNINGS a3 and T. J. NORMAN a3
a1 Department of Computer Science, University of Essex, UK
a2 Department of Mathematical Sciences, University of Memphis, USA
a3 Department of Electronic Engineering, Queen Mary & Westfield College, University of London, UK
Abstract
Cooperation is often presented as one of the key concepts which differentiates multi-agent systems from other related disciplines such as distributed computing, object-oriented systems, and expert systems. However, it is a concept whose precise usage in agent-based systems is at best unclear and at worst highly inconsistent. Given the centrality of the issue, and the different ideological viewpoints on the subject, this was a lively panel which dealt with the following main issues
J. R. R. Tolkien, ecology, and education
No full textJohn Ronald Reul Tolkien (1892-1973) was an Oxford trained philologist, professor (don) at Oxford, noted scholar, and author of high fantasy literature. His The Lord of the Rings trilogy (TLOR) has sold over 150 million copies worldwide making it the second bestselling work of fiction of all time (“The Lord of the Rings,” 2014). His popularity has resurged, though it never really waned, with Peter Jackson’s big screen adaptation of Tolkien’s most famous work The Lord of the Rings (2001-2003), also in trilogy form, winning multiple Oscar Awards, and grossing over 3 billion dollars worldwide (“The Lord of the Rings,” 2014). More recently, Jackson’s three part installments of the precursor to TLOR, The Hobbit (2012-2014), have also proved highly successful in movie format. As has been long noticed by fans and critics alike, Tolkien’s works, TLOR, The Hobbit, The Silmarillion (his legendarium of Middle-earth or Arda), and other lesser known works like The Adventures of Tom Bombadil (TATB) are permeated with ecological themes and tropes. According to Morgan (2010), Tolkien’s ecology is “[grounded in a] creation-centered ethic of stewardship . . . . that holds the potential to re-enchant the world” (p. 383). Further, Morgan (2010) also says, that “The story . . . possesses significant pedagogical potential, albeit implicit in nature" (pp. 383-384). Obviously, at least to many, the Earth is in a state of ecological crisis. My dissertation investigates ecology through select high fantasy works of J. R. R. Tolkien. Specifically, I intend to address what can be construed by studying the enigmatic character of Tom Bombadil, while giving due consideration to other characters who represent or are a party to ecological concerns. This dissertation will prove that the study of Bombadil is a boon to ecological education in the forms of autodidacticism, ecopedagogy, and ecoliteracy by showing readers how the Earth should be treated and with regard to changing our current anthropocentric mindset to one that embraces a respect and reverence for nature; that is, biophilia
A distributed amplifier system for bilayer lipid membrane (BLM) arrays with noise and individual offset cancellation
No full textLipid bilayer membrane (BLM) arrays are required for high throughput analysis, for example drug screening or advanced DNA sequencing. Complex microfluidic devices are being developed but these are restricted in terms of array size and structure or have integrated electronic sensing with limited noise performance. We present a compact and scalable multichannel electrophysiology platform based on a hybrid approach that combines integrated state-of-the-art microelectronics with low-cost disposable fluidics providing a platform for high-quality parallel single ion channel recording. Specifically, we have developed a new integrated circuit amplifier based on a novel noise cancellation scheme that eliminates flicker noise derived from devices under test and amplifiers. The system is demonstrated through the simultaneous recording of ion channel activity from eight bilayer membranes. The platform is scalable and could be extended to much larger array sizes, limited only by electronic data decimation and communication capabilities
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