6,328 research outputs found
Re:Reading piece on author Gunnar Hansen of Northeast Harbor. Hansen wrote I
No full textRe:Reading piece on author Gunnar Hansen of Northeast Harbor. Hansen wrote Islands at the Edge of Time, and recently worked on the screenplay for a documentary produced by the Penobscot Nation
Exercise training in heart failure with preserved ejection fraction patients: the importance of resistance training
No full textExercise training in heart failure with preserved ejection fraction patients: the importance of resistance training
No full textChronic heart failure with preserved ejection fraction (HFpEF) is the dominant form of HF, with an increasing prevalence and until recently very limited management options (e.g. diuretics, gliflozins, and incretin therapies). 1 Exercise intolerance (EI) presents one of the most common symptoms of HFpEF and is associated with a decreased quality of life (QoL) and increased risk of HF-related hospitalization and mortality. 1 The pathophysiology of EI is however complex and consists of pulmonary, skeletal muscle, vascular, and cardiac abnormalities that can substantially impact cardiac output, oxygen transport, and utilization to the exercising muscles, thereby leading to a substantial reduction in peak oxygen consumption (peak VO 2) and muscle strength. 1 This multiorgan dysfunction cannot be remediated by cardiovascular pharmacotherapy or cardiac implantable electronic devices only; therefore , optimal lifestyle management strategies are needed as well to improve the EI-related symptoms and outcomes. 1 Exercise training (ET), as part of cardiac rehabilitation (CR), may alleviate the symptoms of HFpEF and has been associated with superior improvements in (sub)maximal aerobic capacity, muscle strength, and QoL and decreases the risk of all-cause and HF hospitalization in HF patients. 2 Current evidence on ET in CR was established on mostly patients with HF with reduced EF (HFrEF), 2 while the evidence in HFpEF patients is growing. Recently completed studies have demonstrated superior effects of moderate-intensity continuous or high-intensity interval aerobic training (AT) alone or combined with resistance training (RT) on peak VO 2 over standard care alone. 3,4 While these studies have provided important information for improving exercise-based CR in HFpEF, there may be (emerging) ET approaches that should be adopted for this patient group. For example, recent evidence suggests that moderate-to-high load RT [MHL-RT; 55-80% of one repetition maximum (1-RM)] is safe and can provide greater benefits on peak VO 2 and maximal muscle strength, compared with AT alone in coronary artery disease (CAD) patients. 5 Therefore, it remains interesting to assess whether the implementation of MHL-RT may provide additional benefits on exercise performance in HFpEF patients. In this issue of the European Journal of Preventive Cardiology, Palau et al. 6 sought to determine the effects of novel ET approaches on improving symptoms of EI in HFpEF patients, all with chronotropic incompetence (chronotropic index <0.62 or <0.80 for patients previous on or without β-blocker therapy, respectively). The novelty of this paper is that the authors for the first time targeted the chronotropic incompetence with supervised ET intervention. In the study, the authors rando-mized 80 HFpEF patients to exercise counselling alone (counselling on regular unsupervised aerobic and resistance exercise), high-intensity AT alone (twice weekly, intervals of 1 min of high-intensity aerobic exercise separated by 2 min of active recovery), combination of inspiratory muscle training (20 repetitions at 40-60% of maximal inspiratory pressure performed twice daily), AT and low-load RT (LL-RT) (3 sets of 20 repetitions at 30-50% of 1-RM performed twice weekly), or MHL-RT (3 sets of 12 repetitions at 55-75% of 1-RM performed twice weekly). The study assessed changes in peak VO 2 (mL/kg/min and %), QoL, chronotropic response, and safety of and adherence to exercise intervention. After 12 weeks of intervention, all three supervised ET groups improved peak VO 2 max, health-related QoL, and chronotropic response to a greater extent when compared with exercise counselling alone. The combination of home-based inspiratory muscle training with supervised AT and MHL-RT was superior to AT alone on the improvement in peak VO 2 , while all supervised ET interventions induced similar improvements in QoL and chronotropic response, with 38% of the patients in the ET groups restoring their chronotropic response. In addition, all ET interventions were safe, well tolerated (all patients completed more than 83% of prescribed ET sessions) with no adverse cardiovascular events. This study elegantly presents several novel insights into the benefits of concurrent ET methods (e.g. combination of AT and RT) to tackle the highly prevalent EI symptoms of HFpEF patients. First, the study clearly shows that supervised ET should be offered for HFpEF patients instead of exercise counselling alone that showed no clinical benefits. Second, this study demonstrates the importance of combining A
Replication Data for: Living Together, Voting Together: Voters moving in together before an election have higher turnout
No full textThe readme for the replication archive for "Living Together, Voting Together: Voters moving in together before an election have higher turnout"
by Dahlgaard JO, Bhatti Y, Hansen JH and Hansen KM*
published in British Journal of Political Science
Year 2021
*Corresponding author: Department of Political Science, University of Copenhagen, [email protected], www.kaspermhansen.eu. Øster Farimagsgade 5, 1353 Copenhagen K, Denmark, Cell +45 51245005.
The administrative data used for most files are not part of the replication archive as they can not be share according to Statistics Denmark's Terms & Conditions.
PLease see https://www.dst.dk/en/TilSalg/Forskningsservice# about general access to Statistics Denmark data for research
Before Hansen
No full textEven now that it’s been renovated to new glory as the Hansen Student Center, memories of its former life as the Memorial Gymnasium still linger in the 80-year-old building’s nooks and crannies
Rick Hansen visits Nelson
No full textRick Hansen, wheelchair marathon champion, visits Nelson to give a speech to students at L.V. Rogers, June 4, 1982. Hansen's good friend and coach, Tim Frick, was at this time a Selkirk College physical education instructor
Thorkild Hansen
No full textThis is a short presentation of the main works of the Danish author Thorkild Hansen
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