166 research outputs found

    Bowen’s disease – a review of newer treatment options

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    Thorsten Neubert, Percy LehmannZentrum für Dermatologie, Allergologie und Umweltmedizin, Helios Klinikum Wuppertal, Klinikum der Universität Witten-Herdecke, Wuppertal, GermanyAbstract: Bowen’s disease (squamous cell carcinoma in situ) has a 3%–5% risk to develop into invasive squamous cell carcinoma. Non-melanoma skin cancer is the most common cancer among Caucasians and its incidence has increased during the last decades dramatically. Multiple treatment options for Bowen’s disease have been described and are established with advantages and disadvantages. Bowen’s disease occurs more often in elderly patients (with a higher risk of comorbidities) and is frequently located on body sites with poor wound healing. Therefore there is need for non-invasive/non-destructive but effective treatment options. We would like to give an overview of established therapies and more detailed information about the newer treatment options for Bowen’s disease with topical diclofenac, topical imiquimod and photodynamic therapy.Keywords: Bowen’s disease, photodynamic therapy, imiquimod, diclofena

    Einleitung: Zusammenarbeit klug gestalten. Projektmanagement und Digital Humanities

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    Cremer F, Dogunke S, Neubert AM, Wübbena T. Einleitung: Zusammenarbeit klug gestalten. Projektmanagement und Digital Humanities. In: Cremer F, Dogunke S, Neubert AM, Wübbena T, eds. Projektmanagement und Digital Humanities. Zur klugen Gestaltung der Zusammenarbeit. Digital Humanities Research. Vol 9. Bielefeld: Bielefeld University Press; 2024: 7-20

    Euchondrus adwani Eike Neubert & Zuhair Amr 2016, n. sp.

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    Euchondrus adwani n. sp. (Figure 1) Material: Holotype NMBE 539263; paratype NMBE 539264 /1. Type locality: Syria, surrounding of the monastery of Deir Moussa, 34.0219°N 36.8423°E, 1300 m a.s.l., 11.iii. 2010, leg. Adwan Shehab. *Corresponding author. Email: [email protected] © 2016 Taylor & Francis Measurements (holotype): Height = 11.04 mm; diameter = 4.13 mm; peristome height = 4.03 mm; peristome diameter = 2.97 mm; number of whorls = 8. Diagnosis. Euchondrus adwani n. sp. differs from the widespread E. septemdentatus by its conical shell (broadly oval in E. septemdentatus), its flat suture and teleoconch whorls (suture deeper, whorls much more rounded in E. septemdentatus), the heavy palatal labial callus (weaker in E. septemdentatus), the bar-like subangularis (weaker in E. septemdentatus), and the keeled last whorl (rounded in E. septemdentatus). Description: Shell solid, dextral, cylindrical, upper part cylindro-conical in outline; shell pale brownish to horny yellow coloured; 8 rather flat-sided teleoconch whorls, suture flat with a distinct white sutural thread; teleoconch smooth, glossy, last whorl with fine, straight and irregularly spaced striae; aperture subtriangular, peristome strongly thickened by a labial callus, moderately reflected, with a rich dentition (description clockwise): palatum with a small suturalis followed by a conical palatalis superior and a broad infrapalatalis with the latter two denticles placed on a thick callus; columellar side with a basalis and a straight columellaris; parietum with a strong and long parietalis, bordered by a small spiralis, subangularis large, bar-like, left side of the parietum with another small denticle at the attachment site of the peristome; last teleoconch whorl dorsally compressed forming a distinct blunt ridge (arrows); umbilicus slit-like open, periomphalum large, dish-like. Remarks: This species shows some superficial similarities with E. desertorum Rochanaburananda in Forcart, 1981 (Figure 2), which is endemic to the Negev Desert (Heller, 2009). Both species have a straight conical shell, but E. desertorum is considerably larger than E. adwani n. sp. and its aperture is rounded and not subtriangular. It also differs in the formation of the dentition: in E. desertorum, the infrapalatalis is bifid (simple in E. adwani), the spiralis is large and connected to the parietalis (small and disconnected in E. adwani), and the subangularis is weaker (very strong in E. adwani). The last whorl of E. adwani displays a distinct keel with an enlarged periomphalum, while in E. desertorum the dorsum is rounded, and the periomphalum is much smaller. Etymology: This species is named in honour of Dr. Adwan Shawabi, who was a keen collector of molluscs from Syria, and a personal friend, and who was killed in February 2015 in the Syrian civil war (Amr, 2015).Published as part of Eike Neubert & Zuhair Amr, 2016, On a new species of Euchondrus Boettger, 1883 from Syria (Pulmonata: Enidae), pp. 58-60 in Zoology in the Middle East 62 on pages 58-60, DOI: 10.1080/09397140.2015.1132564, http://zenodo.org/record/88703

    Ein Kommentar

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    Neubert AM. Verantwortungsvolles Projektmanagement - schönes Beiwerk oder nötige Erweiterung? In: Cremer F, Dogunke S, Neubert AM, Wübbena T, eds. Projektmanagement und Digital Humanities. Zur klugen Gestaltung der Zusammenarbeit. Digital Humanities Research. Bielefeld, Germany: Bielefeld University Press / transcript Verlag; 2024: 281-308.Die Rahmenbedingungen für Projekte in den Digital Humanities können herausfordernd sein: Zum einen ist die Innovationserwartung beteiligter Institutionen und Fördergeber ungebremst. Zum anderen bedürfen die Koordination interdisziplinärer, komplexer Großvorhaben sowie der Aufbau von Forschungsinfrastruktur und -services einer Professionalisierung des Projektmanagements. Die Beiträger*innen geben Einblicke in unterschiedliche Praktiken und versammeln Sichtweisen aus der Fachcommunity. Damit gehen sie den ersten Schritt, um das Tätigkeitsfeld in den deutschsprachigen Fachdiskurs zu holen - und zeigen durch theoriegeleitete Reflexionen methodologische Ansätze zu einer Weiterentwicklung des Wissenschaftsmanagements auf

    Leiostyla eikenboomi Ruud, Menkhorst & Neubert, 2016, spec. nov.

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    Leiostyla eikenboomi spec. nov. (Fig. 3) Type locality & type specimens. – Turkey, Vilayet Karabük, Suçatı Tüneli 9 km ESE. Yenice, 190 m (41.1897°N 32.4349°E), H.P.M.G. Menkhorst leg., 22.x.2008. Holotype NMBE 544682, paratypes NMBE 544644/2. Diagnosis. – A conic, densely ribbed Leiostyla species with a prominent angular lamella, as well as a prominent parietalis, palatalis inferior, and columellaris; a basalis and supracolumellaris is missing and there is a prominent two-peaked thickening between the columellar insertion of the peristome and the angular lamella. Description. – Shell dextral, conic in outline, with closely, distinctly and regularly, oblique ribbing; there are no spiral striae. The 6.7-7.2 whorls are convex and separated by a deep suture. Shell rather solid, not or hardly translucent, dark horn-coloured. The last whorl has a lengthy but shallow gutter, corresponding in its position to the palatalis inferior on the outer wall, but there is no distinct basal keel. Umbilicus open, deep and narrow. Peristome strongly reflected at right angles to form a flat, thickened, somewhat yellowish coloured lip. Columellar and palatal insertion connected by a clearly visible parietal callus. Angular lamella prominent, high, without appendages; it almost reaches the border of the parietal callus. The angular lamella is fused with a sharp, triangle-like subangularis that faces the palatal wall and that on its turn is fused with the palatal insertion of the peristome. The subangularis creates a small sinulus. A small sinulus at the columellar insertion of the peristome is created by a two-peaked prominent thickening situated below the border of the parietal callus. Parietalis prominent, high, rather deep inside the aperture; it is not connected with the angular lamella. Palatalis inferior very long and well developed; it just stops in front of the lip (i.e. it does not fuse with it). A very small, dot-like palatalis superior is present just above the anterior end of the palatalis inferior, close to the thickened lip. The columellaris is horizontally projected above the middle of the columellar side of the aperture. There is a marked thickening below the parieto-palatal angle of the peristome. Measurements (n = 2). – Holotype: H = 3.4; LWH = 1.8; MH = 1.4; LWD = 1.9; LWM = 2.0; MD = 1.2; NW = 7.2. Paratype: H = 3.3; LWH = 1.8; MH = 1.4; LWD = 1.9; LWM = 2.1; MD = 1.3; NW = 6.7. Localities. – Known from the locus typicus only (see above). Derivatio nominis. – Named after Joop C.A. Eikenboom, a well-known Dutch malacologist and for forty years an inspiring friend of the second author. Differentiation. – Leiostyla superba differs from L. eikenboomi by its more densily packed and finer ribbing, the less conical outline, the denticulate peristome, the presence of a basalis and supracolumellaris, the more prominent palatalis superior, the more prominent tooth-like thickening of the palatal peristome just above the palatalis superior, and the missing of a two-peaked thickening below the border of the parietal callus. Leiostyla zilchi differs from L. eikenboomi by the presence of a basalis and supracolumellaris, the more developed palatalis superior, and the missing two-peaked thickening below the border of the parietal callus.Published as part of Ruud, A. Bank, Henk P. M. G Menkhorst & Eike Neubert, 2016, Descriptions of new and little-known land snail taxa from Turkey, and establishment of a new genus (Gastropoda, Pulmonata: Lauriidae, Enidae and Vitrinidae), pp. 5-30 in Basteria 80 (1) on page 8, DOI: 10.5281/zenodo.43974

    Relaxation, especially dielectric behaviour of polymer composites and liquid crystalline polymers

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    Title: Relaxation, especially dielectric behaviour of polymer composites and liquid crystalline polymers Author: Milan Neubert Department: Department of Macromolecular Physics Supervisor: doc. RNDr. Jan Nedbal, CSc., Department of Macromolecular Physics Abstract: The subject of the work was to study the relaxation electrical properties of polymer composites and liquid crystalline polymers. Work focused on till now not deeply explored new polymeric materials - on semi-aromatic poly (ester amides) and on composites of poly(vinyl alcohol) with polyaniline. In the case of poly(ester amides), we had three series with different aromatic groups and different length of the aliphatic chain, in the case of composite materials, we studied composites prepared as cryogels. Basic experimental method was dielectric spectroscopy, supplemented by approaches of electrochemical impedance spectroscopy. A noncontact measuring method based on eddy currents was newly developed, that is able to provide information about both the conductivity and permittivity of samples, and a measuring cell was constructed, later used to perform part of the experimental work. Keywords: permittivity, conductivity, dielectric spectroscopy, liquid crystalline polymers, conducting polymer composite

    Projektmanagement und Digital Humanities. Zur klugen Gestaltung der Zusammenarbeit

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    Cremer F, Dogunke S, Neubert AM, Wübbena T, eds. Projektmanagement und Digital Humanities. Zur klugen Gestaltung der Zusammenarbeit. Digital Humanities Research. Vol 9. Bielefeld: Bielefeld University Press; 2024.Die Rahmenbedingungen für Projekte in den Digital Humanities können herausfordernd sein: Zum einen ist die Innovationserwartung beteiligter Institutionen und Fördergeber ungebremst. Zum anderen bedürfen die Koordination interdisziplinärer, komplexer Großvorhaben sowie der Aufbau von Forschungsinfrastruktur und -services einer Professionalisierung des Projektmanagements. Die Beiträger*innen geben Einblicke in unterschiedliche Praktiken und versammeln Sichtweisen aus der Fachcommunity. Damit gehen sie den ersten Schritt, um das Tätigkeitsfeld in den deutschsprachigen Fachdiskurs zu holen – und zeigen durch theoriegeleitete Reflexionen methodologische Ansätze zu einer Weiterentwicklung des Wissenschaftsmanagements auf

    Front Matter

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    Cover, table of contents, author biographies, portrait of Father Emile (Emil) Neubert, S.M., S.T.D (1878-1967

    Radio occultation bending angle anomalies during tropical cyclones

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    The tropical deep convection affects the radiation balance of the atmosphere changing the water vapor mixing ratio and the temperature of the upper troposphere lower stratosphere. The aim of this work is to better understand these processes and to investigate if severe storms leave a significant signature in radio occultation profiles in the tropical tropopause layer. Using tropical cyclone best track database and data from different GPS radio occultation missions (COSMIC, GRACE, CHAMP, SACC and GPSMET), we selected 1194 profiles in a time window of 3 h and a space window of 300 km from the eye of the cyclone. We show that the bending angle anomaly of a GPS radio occultation signal is typically larger than the climatology in the upper troposphere and lower stratosphere and that a double tropopause during deep convection can easily be detected using this technique. Comparisons with co-located radiosondes, climatology of tropopause altitudes and GOES analyses are also shown to support the hypothesis that the bending angle anomaly can be used as an indicator of convective towers. The results are discussed in connection to the GPS radio occultation receiver which will be part of the Atomic Clock Ensemble in Space (ACES) payload on the International Space Station. © Author(s) 2011

    Correction to: Magnetic Characterization of Ferromagnetic Shape Memory Components Under Defined Mechanical Loading

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    S.353The article ""Magnetic Characterization of Ferromagnetic Shape Memory Components Under Defined Mechanical Loading"", written by Fabian Ehle, Peter Neumeister, Eric Haufe, and Holger Neubert was originally published electronically on the publisher's internet portal on 29 January, 2020 without open access. With the author(s)' decision to opt for Open Choice the copyright of the article changed on 08 April 2021 to ©The Author(s) 2020 and the article is forthwith distributed under a Creative Commons Attribution 4.0. International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons License, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons License, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons License and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. The original article has been corrected.7Nr.
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