10,352 research outputs found
Short-term alteration in voluntary feed intake after selenium supplementation in Angora goat kids
No full textThe objective of this study was to examine the effect of selenium (Se) supplementation on voluntary feed intake in Se-deficient Angora goat kids and its temporal relationship to alterations in the concentrations of thyroid hormones in plasma and the activity of glutathione peroxidase in serum. Angora goat kids were fed pelleted lucerne with a Se concentration of 20 mu g/kg of dry matter (DM) and treated orally with either Se (0.1 mg/kg of liveweight weekly, as sodium selenate) or deionised water. Supplementation with Se had no effect on DM intake measured over 21 days. Serum activity of glutathione peroxidase was increased by Day 1 of treatment (P < 0.001), plasma concentration of thyroxine was decreased by Day 21 of treatment (P < 0.01), and plasma concentration of triiodothyronine was unaffected by treatment. It is concluded that increased appetite is unlikely to be the primary mechanism involved in the response to Se supplementation in Angora goats.PT: J; CR: *SAS I INC, 1988, SAS US GUID STAT VER ARTHUR JR, 1993, AM J CLIN NUTR S, V57, P236 BUNK MJ, 1980, J NUTR, V110, P743 DONALD GE, 1993, AUST J EXP AGR ANIM, V33, P411 EWAN RC, 1976, J NUTR, V106, P702 HAFEMAN DG, 1974, J NUTR, V104, P580 HUSSEIN KSM, 1982, ACTA AGR SCAND, V23, P556 THOMPSON JN, 1969, J NUTR, V97, P335 THOMPSON KG, 1980, RES VET SCI, V28, P321 UNDERWOOD EJ, 1977, TRACE ELEMENTS HUMAN WALSH DM, 1993, INT J VITAM NUTR RES, V63, P188 WICHTEL JJ, 1995, IN PRESS J DAIRY SCI WICHTEL JJ, 1996, NEW ZEAL J AGR RES, V39, P111; NR: 13; TC: 1; J9: N Z J AGR RES; PG: 4; GA: UM341Source type: Electronic(1
Cost-effectiveness of the National Health Service Abdominal Aortic Aneurysm Screening Programme in England.
No full textBACKGROUND: Implementation of the National Health Service abdominal aortic aneurysm (AAA) screening programme (NAAASP) for men aged 65 years began in England in 2009. An important element of the evidence base supporting its introduction was the economic modelling of the long-term cost-effectiveness of screening, which was based mainly on 4-year follow-up data from the Multicentre Aneurysm Screening Study (MASS) randomized trial. Concern has been expressed about whether this conclusion of cost-effectiveness still holds, given the early performance parameters, particularly the lower prevalence of AAA observed in NAAASP. METHODS: The existing published model was adjusted and updated to reflect the current best evidence. It was recalibrated to mirror the 10-year follow-up data from MASS; the main cost parameters were re-estimated to reflect current practice; and more robust estimates of AAA growth and rupture rates from recent meta-analyses were incorporated, as were key parameters as observed in NAAASP (attendance rates, AAA prevalence and size distributions). RESULTS: The revised and updated model produced estimates of the long-term incremental cost-effectiveness of £5758 (95 per cent confidence interval £4285 to £7410) per life-year gained, or £7370 (£5467 to £9443) per quality-adjusted life-year (QALY) gained. CONCLUSION: Although the updated parameters, particularly the increased costs and lower AAA prevalence, have increased the cost per QALY, the latest modelling provides evidence that AAA screening as now being implemented in England is still highly cost-effective
Paul et al. 2020. Bioacoustics Data
No full textDatasets to reproduce results from: Paul, N. Thompson, MJ. Foote, JR. 2020. Bioacoustics. Characterizing the flight song: repeatable individual variation of Ovenbird song features
Recognition, Identity and Subjectivity
No full textThe term “recognition” has in the last two or three decades become the centre point of an extraordinary amount of theoretical activity among critical theorists and social and political philosophers. It is also at the centre of a great deal of conceptual ambivalence and often theoretical confusion as not all authors mean the same thing with the term and as there is often inadequate attention to the different concepts at stake. In this chapter, the author maps central parts of the conceptual and theoretical landscape around the term “recognition”, which is relevant for critical theory, and discuss some of the main contemporary authors on the theme: Axel Honneth, Charles Taylor, Nancy Fraser and Judith Butler
Recommended from our members
Status of the 9 MJ Range Gun System
No full textThe 9 MJ Range Gun system under construction at the Center for Electromechanics at The University of Texas at Austin is designed as a self-contained, field portable electromagnetic launch system to accelerate a salvo of three projectiles to a muzzle energy of 9 MJ at velocities ranging from 2.5 to 4.0 km/s. The Range Gun system will consist of a self-excited air-core compulsator, a 90 mm bore railgun launcher, prime power and auxiliary systems, solid state switches for field rectification and gun discharge, and the controls and data acquisition required to operate the system. The compulsator is designed to deliver 3.2 MA current pulses to the railgun launcher at a peak power rating of 10 GW. This paper describes some of the innovations incorporated into the design of the 9 MJ Range Gun system compulsator and presents the status of the fabrication and testing efforts. Initial performance of the 90 mm railgun during testing at the Electric Armaments Research Center will also be presented.Center for Electromechanic
Self-compression of 4.9 µm pulses to sub-40 fs with 2 mJ energy in Zinc Sulfide
No full textNonlinear self-compression of few-cycle multi-mJ pulses at 4.9 µm in ZnS is presented. 80 fs input pulses are compressed to 37 fs with 2.1 mJ energy at a 1 kHz repetition rate. © 2024 The Author(s
Edward Thompson, MI5 and the Reasoner controversy: negotiating “Communist principle” in the crisis of 1956
No full textThe sixtieth anniversary of the 1956 crisis in international communism provoked a fresh wave of comment on its British dimensions and coincided with the declassification of MI5 files on party historians Edward Thompson and Rodney Hilton. This article approaches the question of communist commitment through a reinterpretation of the Reasoner controversy in which Thompson and Hilton were to different degrees involved. First, it uses the MI5 material alongside existing sources to illuminate tactical and political aspects of the engagement between the Reasoner editors and the party leadership, placing emphasis on the Reasoner’s role as bridgehead of an attempt to reform the party from within rather than as simply a precursor to the New Left.. Next, interrogating Thompson’s claim to ‘communist principle’, it compares his developing interpretation of what this meant and required with the views of a selection of other intellectuals. Far from representing a straightforward assertion of moral conscience against monolithic party bureaucracy, the Reasoner controversy reveals an extremely complex picture of the tensions and constraints involved in communist commitment
Influence of Physical Activity on Human Sensory Long-Term Potentiation
No full textSmallwood N, Spriggs MJ, Thompson CS, et al. Influence of Physical Activity on Human Sensory Long-Term Potentiation. Journal of the International Neuropsychological Society. 2015;21(10):831-840
Biopsy confirmation of metastatic sites in breast cancer patients:clinical impact and future perspectives
No full textDetermination of hormone receptor (estrogen receptor and progesterone receptor) and human epidermal growth factor receptor 2 status in the primary tumor is clinically relevant to define breast cancer subtypes, clinical outcome, and the choice of therapy. Retrospective and prospective studies suggest that there is substantial discordance in receptor status between primary and recurrent breast cancer. Despite this evidence and current recommendations, the acquisition of tissue from metastatic deposits is not routine practice. As a consequence, therapeutic decisions for treatment in the metastatic setting are based on the features of the primary tumor. Reasons for this attitude include the invasiveness of the procedure and the unreliable outcome of biopsy, in particular for biopsies of lesions at complex visceral sites. Improvements in interventional radiology techniques mean that most metastatic sites are now accessible by minimally invasive methods, including surgery. In our opinion, since biopsies are diagnostic and changes in biological features between the primary and secondary tumors can occur, the routine biopsy of metastatic disease needs to be performed. In this review, we discuss the rationale for biopsy of suspected breast cancer metastases, review issues and caveats surrounding discordance of biomarker status between primary and metastatic tumors, and provide insights for deciding when to perform biopsy of suspected metastases and which one (s) to biopsy. We also speculate on the future translational implications for biopsy of suspected metastatic lesions in the context of clinical trials and the establishment of bio-banks of biopsy material taken from metastatic sites. We believe that such bio-banks will be important for exploring mechanisms of metastasis. In the future, advances in targeted therapy will depend on the availability of metastatic tissue
Correction to: Chamoun et al., Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection
No full textChamoun MN, Blumenthal A, Sullivan MJ, Schembri MA, Ulett GC. 2018. Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology. https://doi.org/10.1080/1040841X.2018.1426556.
When the above article was first published online, the below three corrections were missed.
The author ‘Antje Blumenthal’ was wrongly affiliated to the affiliation “cSchool of Chemistry and Molecular Biosciences, and Australian Infectious Disease Research Centre, The University of Queensland, Brisbane, Australia”. Now this affiliation has been removed for this author.
The affiliation ‘bTranslational Research Institute, The University of Queensland Diamantina Institute, Woolloongabba, Australia’ of the author ‘Antje Blumenthal’ should read ‘bThe University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia’.
In Table 3, the sentence ‘Benefit of manipulating IL-17 levels to improve immunization strategies M. tuberculosis’ should read “Benefit of manipulating IL-17 levels to improve immunization strategies against M. tuberculosis”.No Full Tex
- …
