2,580 research outputs found
Opposing roles for specific TIMPs in breast cancer prognostic
No full textThe two articles (Span et al. 2004 and Schrohl et al.
2004) highlight the complexity and specificity of
matrix metalloproteinases (MMPs) and TIMPs in
cancer biology, diagnosis, and treatment. Both provide
novel insights into these issues by focussing on
TIMPs rather than MMPs and extend a growing
number of reports that the roles played by TIMPs in
tumour pathology may be much broader than the
inhibition of MMP action on the extracellular matrix
(ECM), and may extend to the regulation of MMP
influence on many systems and potentially to MMPindependent
functions. Specific TIMP-3 involvement
in tamoxifen-induced apoptosis strongly contrasts
the association between elevated TIMP-1 levels with
poor outcome in breast cancer. Although candidate
apoptotic mechanisms may elegantly explain the effect
of TIMP-3 results, the reasons underlying the TIMP-1
result remain to be fully elucidated
Automation of NLO QCD and EW corrections with Sherpa and Recola
No full textAbstract This publication presents the combination of the one-loop matrix-element generator Recola with the multipurpose Monte Carlo program Sherpa. Since both programs are highly automated, the resulting Sherpa +Recola framework allows for the computation of – in principle – any Standard Model process at both NLO QCD and EW accuracy. To illustrate this, three representative LHC processes have been computed at NLO QCD and EW: vector-boson production in association with jets, off-shell Z -boson pair production, and the production of a top-quark pair in association with a Higgs boson. In addition to fixed-order computations, when considering QCD corrections, all functionalities of Sherpa, i.e. particle decays, QCD parton showers, hadronisation, underlying events, etc. can be used in combination with Recola. This is demonstrated by the merging and matching of one-loop QCD matrix elements for Drell–Yan production in association with jets to the parton shower. The implementation is fully automatised, thus making it a perfect tool for both experimentalists and theorists who want to use state-of-the-art predictions at NLO accuracy
Light-time effect in two eclipsing binaries: NO Vul and EW Lyr
No full text32nd International Physics Congress of Turkish-Physical-Society (TPS) -- SEP 06-09, 2016 -- Bodrum, TURKEYIn this study, orbital period variations of two eclipsing binary systems (NO Vul and EW Lyr) were discussed. Possible light time effects due to third bodies in these systems were re-examined. The mass function and orbital period of hypothetical third bodies were calculated to be 0.000627 +/- 1.000003 M-circle dot, 26.17 +/- 0.05 years and 0.12682 +/- 0.00003 M-circle dot, 77.23 +/- 0.72 years for NO Vul and EW Lyr, respectively.Turkish Phys So
Exact analytical solutions of the fractional biological population model, fractional EW and modified EW equations
No full textIn this paper, exact analytical solutions of the biological population model, the EW and the modified EW equations with a conformable derivative operator have been examined by means of the trial solution algorithm and the complete discrimination system. Dark, bright and singular traveling wave solutions of the equations have been obtained by algorithm. Also, revealed singular periodic solutions have been listed. All solutions were verified by substituting them into their corresponding equation via Mathematica package program. © 2021 Balikesir University. All rights reserved.The author would like to thank to Ege University, Scientific Research Project (BAP) for the support on the Project 17-TKMYO-002
Dataset references for EW-MFA study on Jura canton
No full textSources for datasets used for EW-MFA project on Jura canton. If a data source is confidential or doesn't have a link, please contact the author
The tumble mode - where test pilots fear to tread
No full textFollowing a fatal accident in 1997 and identification of common patterns in several (usually fatal) previous accidents the AAIB (United Kingdom Air Accidents Investigation Branch) asked the BMAA (British Microlight Aircraft Association) to pursue a course of investigation into the tumble mode, which had been attributed as the primary cause of that fatal accident.
The tumble mode is a peculiarity of weightshift controlled aircraft - that is flexwing microlights and hang-gliders. It is a departure from controlled flight leading to a nose-down pitch autorotation: pitch rates of 400°/s are known. When a tumble occurs in a microlight aeroplane, it is rare for the crew to survive and loss of the aircraft is universal
The association of the kynurenine pathway of tryptophan metabolism with acute brain dysfunction during critical illness.
No full textInsulin-like growth factor-1 and delirium in critically ill mechanically ventilated patients: a preliminary investigation
No full textInsulin-like growth factor-1 and delirium in critically ill mechanically ventilated patients: a preliminary investigation.
No full textPlasma tryptophan and tyrosine levels are independent risk factors for delirium in critically ill patients.
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