138,675 research outputs found
Electrical conductivity measurement in Thiel-embalmed tissue model : relevance to radiofrequency ablation
No full textPA gratefully acknowledges SUPA for funding his Advanced Research Fellowship.Thiel-embalmed human cadaveric specimens are used widely for biomedical scientific investigation. This Letter reports electrical impedance measurements of Thiel-embalming solutions from 1 Hz to 32 MHz. Compared with other solutions studied, Thiel solution has the lowest impedance throughout the test spectrum. The electrical conductivity of a Thiel-embalmed liver sample exhibited a relatively flat frequency response from 100 to 500 kHz, which is the frequency range used for electro-surgery and radiofrequency tumour ablation (RFA). It measured 5 Sm-1 compared with 0.22 Sm-1 obtained from ex-vivo fresh pig liver. Using finite element modelling and experimental evaluation, the ablation zone obtained from the Thiel-embalmed liver sample was extremely small due to its much higher conductivity. Hence, it is concluded that Thiel-embalmed tissue cannot be used as a reliable model for RFA evaluation.Peer reviewe
From "silent teachers" to models
No full textFor decades, embalmed cadavers have played an important role in teaching anatomy to the scientists and doctors of the future. Most anatomy departments use a traditional formaldehyde-based embalming method, but formalin embalming makes the bodies very rigid, which limits their usefulness for procedures other than dissection. A more recent embalming method developed by W. Thiel has allowed these "silent teachers" to take on a further role in applied anatomy research and teaching: to act as models for surgical training and medical research
Francavilla A, Di Leo A, Wu SQ, Ove P, Van Thiel D, Sciascia C, Starzl TE.
No full textDuring regeneration of rat livers following 70% hepatectomy, insulin binding sites on hepatocyte plasma membranes are increased after 24-48 hours, glucagon binding sites are reduced on days 2-8, and the resultant insulin/glucagon binding ratio is markedly increased. An apparent paradox was the finding of a depression of the activity of an insulin associated enzyme, glucokinase, at a time when the number of insulin binding sites was increased
A. Rogers et D. Durand de Bousingen, Une bioéthique pour l'Europe, 1995
No full textThiel Marie-Jo. A. Rogers et D. Durand de Bousingen, Une bioéthique pour l'Europe, 1995. In: Revue des Sciences Religieuses, tome 70, fascicule 2, 1996. p. 291
D. Mieth, Die Diktatur der Gene. Biotechnik zwischen Machbarkeit und Menschenwürde, 2001
No full textThiel Marie-Jo. D. Mieth, Die Diktatur der Gene. Biotechnik zwischen Machbarkeit und Menschenwürde, 2001. In: Revue des Sciences Religieuses, tome 77, fascicule 1, 2003. pp. 117-118
D. Mieth, Was wollen wir können ? Ethik im Zeitalter der Biotechnik, 2002
No full textThiel Marie-Jo. D. Mieth, Was wollen wir können ? Ethik im Zeitalter der Biotechnik, 2002. In: Revue des Sciences Religieuses, tome 77, fascicule 1, 2003. p. 118
D. Sicard, Hippocrate et le scanner. Réflexions sur la médecine contemporaine, 1999
No full textThiel Marie-Jo. D. Sicard, Hippocrate et le scanner. Réflexions sur la médecine contemporaine, 1999. In: Revue des Sciences Religieuses, tome 74, fascicule 1, 2000. Bioéthique et christianisme. pp. 135-136
D. Müller, L'éthique protestante dans la crise de la modernité. Généalogie, critique, reconstruction, 1999
No full textThiel Marie-Jo. D. Müller, L'éthique protestante dans la crise de la modernité. Généalogie, critique, reconstruction, 1999. In: Revue des Sciences Religieuses, tome 74, fascicule 1, 2000. Bioéthique et christianisme. pp. 131-132
Evaluation of Thiel cadaveric model for MRI-guided stereotactic procedures in neurosurgery
No full textMagnetic resonance imaging (MRI)-guided deep brain stimulation (DBS) and high frequency focused ultrasound (FUS) is an emerging modality to treat several neurological disorders of the brain. Developing reliable models to train and assess future neurosurgeons is paramount to ensure safety and adequate training of neurosurgeons of the future
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