1,796,375 research outputs found
The Jackson Laboratory For Genomic Medicine : celebrating five years of discovery
Get PDFCommemorating the five year anniversary of The Jackson Laboratory for Genomic Medicine in Farmington, CT
Empowering Medicine, the 2018 Annual Report of The Jackson Laboratory
Get PDFThe 2018 Annual Report from The Jackson Laboratory (JAX), which highlights some of the major events and accomplishments of the year
In collaboration: the Jackson Laboratory Craniofacial Resource.
No full textDr. Sandy C. Marks, Jr., has been a longtime collaborator of the Mouse Mutant Resource at The Jackson Laboratory and, most recently, was involved in the development of a Craniofacial Resource at TJL. The goals of this resource are to discover and supply to the scientific community mouse models of human craniofacial disease. A brief description of this collaboration is presented in Sandy\u27s honor
Jonah and his friends at The Jackson Laboratory
Get PDFJonah, on the cover, may be the oldest mouse that ever lived. He has helped scientists learn about what happens when people get older. Jonah has made a lot of frends at The Jackson Laboratory and would like you to meet them and color them.
If you don\u27t want to color inside the lines, that is fine with Jonah. He knows many scientists and some of them made very important discoveries because they grew up coloring outside the lines.
Jonah\u27s picture on the cover was colored by Ailish Fahey, age eight, the daughter of Jim Fahey who works at The Jackson Laboratory. Jane Weinberger, who publishes books for children, picked the cover and the 10 other finalists who colored the pictures on the back cover.
Karen Davis, one of Jonah\u27s many friends, drew all the pictures, Bob Gottlieb wrote the words
Exploration of the Patient-Derived Xenografts at the Jackson Laboratory
No full textThe patient-derived xenograft (PDX) tumor model has been described as being more predictive of both human cancer biology and patient response to treatment [4]. The increasing need for the development of anti-cancer agents emphasizes the importance of the utilization of this model type. The Jackson Laboratory PDX collection consists of 770 data points from 264 different models and includes information regarding the growth rates of each model, as well as the clinical diagnoses of each corresponding tissue donor. The objective of this study was to characterize this collection and determine the relationship between growth rates and primary location of cancer within tissue donor. Three parameters of interest were highlighted: doubling time, latency and T1000. It was concluded that these parameters are not dependent on one another, indicating variable rates of growth over time. In addition, majority of models showed similar asymmetric patterns of growth, with peak frequencies between 10.1-20 days for doubling time and latency and 50.1-100 days for T1000. Future researchers should aim to include additional data from all primary site locations, as well as other ethnic groups
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