173,093 research outputs found

    Rufus C. Thayer

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    Thayer, Alexander Wheelock - Porträt im Halbprofil

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    THAYER, ALEXANDER WHEELOCK - PORTRÄT IM HALBPROFIL Thayer, Alexander Wheelock - Porträt im Halbprofil ( -

    The Ralston Ralstonian

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    Weekly newspaper from Ralston, Oklahoma that includes local, state, and national news along with advertising

    For love alone [music] : song /

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    A.H. & C. Ltd. 11361-C (Publisher number). Cover title.; "No. 2 in C".; Lyrics also printed as text on cover verso.; Pl. no.: A.H & C. Ltd. 11361-C.; Also available online http://nla.gov.au/nla.mus-vn1925268

    You're mine for ever [music] : song /

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    A.H. & C. Ltd. 11400-D (Publisher number). Cover title.; Pl. no.: A.H. & C. Ltd. 11400-D.; Also available online http://nla.gov.au/nla.mus-vn326266

    Snowbird [music] : a North American Indian song of the Great Lakes /

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    A.H. & C. Ltd. 11402-A-flat (Publisher number). Cover title.; "No. 2 in A-flat".; "Sung and recorded by Peter Dawson - record no. H.M.V.-EA3737".; Pl. no.: A.H. & C. Ltd. 11402-A-flat.; Also available online http://nla.gov.au/nla.mus-vn327538

    Fear-induced bradycardia in mental disorders: foundations, current advances, future perspectives

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    Fear-induced bradycardia, a transient heart rate deceleration related to a threatening event, is a powerful technique used to assess fear conditioning in humans. During the last century, studies highlighted its usefulness, even when applied to patients with various psychiatric disorders. Here, we provide an insight into these first steps in the field as well as modern works, which helped in refining the methodology. As data is still limited, future endeavors will continue to deepen the knowledge on fear-induced bradycardia and ensure its use as a biomarker to expedite and improve psychiatric interventions, thus lowering the socio-economic burden associated with these disorders

    Genetic differences associated with dopamine and serotonin release mediate fear-induced bradycardia in the human brain

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    Fear-induced bradycardia, a transient heartbeat deceleration following exposure to threat, is a physiological index observable in humans, especially in fear conditioning experiments. While gaining interest in recent years, it is still currently underemployed in neuroscientific research compared to more popular physiological indices. Besides its use in research, it could also constitute a valuable resource in a clinical psychiatry setting, as many disorders are also characterized by altered heart rate responses. However, differences in fear-induced bradycardia may also be subtended by genetic interindividual differences, thus suggesting precaution when recommending its use in the clinical setting. Here, we discussed the first endeavors that aimed at clarifying the genetic underpinnings of heart rate variations, which suggest that individual genetic differences have a role in defining the characteristics of heart rate responses. Given this, translating heart rate measurements in the clinical setting must be implemented with caution. Future endeavors in this field will aim at identifying these differences even further, thus allowing for more precise clinical interventions
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