278 research outputs found
Data Set of PLOS Computational Paper PCOMPBIOL-D-18-02181R1
No full textFigures Data of PLOS Computational paper:Modeling of the axon plasma membrane structure and its effects on protein diffusionAuthors: Yihao Zhang, Anastasios V. Tzingounis, and George LykotrafitisCorresponding Author: George Lykotrafitis, Ph.D.University of ConnecticutStorss, CT UNITED STATES</div
The state of modern Greek language as spoken in Victoria
No full textDeposited with permission of the author. © 1986 Dr. Anastasios TamisThis thesis reports a sociolinguistic study, carried out between 1981 and 1984, of the state of the Modern Greek (MG) language in Australia, as spoken by native-speaking first-generation Greek immigrants in Victoria. Particular emphasis is given to the analysis of those characteristics of the linguistic behaviour of these Greek Australians which can be attributed to the contact with English and to other environmental, social and linguistic influence. (For complete abstract open document
New historical evidence for Anastasios Emm. Papas
No full textNo AbstractThe author’s attention has been drawn to the existence of this historicalevidence in the National Archives of Vienna, by his friend the writer EteoclesGregoriadis together with the numbers of the relevant files. Most of the documents were written in the old German script. Thus the author asked for the help of his friend and former colleague at the University of Thessaloniki and director of the Goethe Institute, Graf Kurt v. Posadowsky, for reading andstudying those documents. Without his help this study would have been impossible. This new evidence concerns the sojourn of Anastasios Papas·—son of Emmanuel Papas, leading figure of the Greek Revolution—in Austria andGermany between the 3rd January and 11th March 1822. There is informationabout his short imprisonment in Trieste, after his arival from Vienna. He then visits various towns in Germany and after negotiations with the Philhellene professor Fr. Thiersch in Munich, he purchases large quantities of ammunition to be despatched to Greece. He finally arrives in Greece early in 1824, and takes part—together with his three brothers who were already fighting—in the struggle for the liberation of the common great fartheland
Insulin degludec U100 is associated with lower risk for severe and symptomatic hypoglycemia as compared with insulin glargine U100 in subjects with type 1 diabetes
No full textInsulin degludec U100 is associated with lower risk for severe and symptomatic hypoglycemia as compared with insulin glargine U100 in subjects with type 1 diabetes
No full textΝέα μέθοδος αντιμετώπισης των χρόνιων διαβητικών ελκών, βασισμένη στη θεραπεία με RGTA matrix: μία τυχαιοποιημένη, ελεγχόμενη μελέτη
No full textΤα έλκη αποτελούν συχνή επιπλοκή του σακχαρώδους διαβήτη (ΣΔ). Τα διαβητικά έλκη χαρακτηρίζονται από αυξημένη δραστηριότητα πρωτεϊνών που διασπούν την εξωκυττάρια θεμέλια ουσία (ΕΘΟ) και δυσχεραίνουν την επούλωση. Τα matrix therapy regenerating agents (RGTA) (CACIPLIQ) είναι χημικά κατασκευασμένα πολυμερή που έχουν σχεδιαστεί ειδικά για να αντικαταστήσουν τη θειική ηπαράνη στα έλκη και έτσι να μιμούνται τη δράση της, προστατεύοντας τις πρωτεΐνες της ΕΘΟ από την αποδόμηση. Στόχος της παρούσας εργασίας ήταν η αξιολόγηση της αποτελεσματικότητας και της ασφάλειας χορήγησης CACIPLIQ σε χρόνια διαβητικά έλκη. Στη μελέτη συμπεριλήφθηκαν 27 ασθενείς με ΣΔ και ενεργό νευροπαθητικό έλκος άκρου ποδός που είχε διάρκεια >6 εβδομάδες. Η μελέτης διήρκησε 16 εβδομάδες και η πρώτη επίσκεψη πραγματοποιήθηκε 2 εβδομάδες πριν την έναρξη της παρέμβασης, ενώ η τελευταία επίσκεψη πραγματοποιήθηκε 4 εβδομάδες μετά το τέλος της παρέμβασης. Συνολικά 13 άτομα τυχαιοποιήθηκαν στην ομάδα που αντιμετωπίσθηκε με τη συνήθη αγωγή και 14 άτομα στην ομάδα που έλαβε επιπλέον CACIPLIQ με τη μορφή εναιωρήματος. Οι ασθενείς των δυο ομάδων δεν διέφεραν σημαντικά ως προς τα δημογραφικά, τα κλινικά και τα εργαστηριακά χαρακτηριστικά τους στην έναρξη της μελέτης. Δεν παρατηρήθηκε σημαντική διαφορά μεταξύ των δυο ομάδων στο πρωτογενές καταληκτικό σημείο που αφορούσε τον αριθμό των ελκών με > 80% μείωση στο μέγεθος του έλκους 10 εβδομάδες μετά τη χορήγηση του εξεταζόμενου φαρμάκου (P = 0.936). Επίσης, δεν παρατηρήθηκε σημαντική διαφορά στα δευτερογενή καταληκτικά σημεία, συμπεριλαμβανομένου και των ανεπιθύμητων συμβαμάτων. Συμπερασματικά, η προσθήκη CACIPLIQ στην καθιερωμένη αγωγή σε νευροπαθητικά έλκη ατόμων με ΣΔ δεν επηρεάζει σημαντικά την έκβαση των ελκών σε σύγκριση με τη συνήθη αγωγή.Ulcers are a common complication of diabetes mellitus (DM). In diabetic ulcers, there is increased activity of proteins that disrupt the extracellular matrix (ECM) and impair wound healing. Matrix therapy regenerating agents (RGTA) (CACIPLIQ) are chemically formulated polymers specifically designed to replace heparin sulfate in ulcers and thereby mimic its action by protecting ECM proteins. The aim of this study was to evaluate the efficacy and safety of CACIPLIQ in chronic neuropathic diabetic ulcers. A total of 27 patients with DM and active foot neuropathic ulcer lasting >6 weeks were recruited. The duration of the study was 16 weeks; the first visit was 2 weeks before the intervention and the last visit was 4 weeks after the end of the intervention. A total of 13 of these patients were randomized to standard care and 14 to CACIPLIQ via spraying as add on standard care. The patients of the two groups did not differ significantly in their demographic, clinical and laboratory characteristics at baseline. No significant difference was found between the two groups regarding the primary endpoint (number of ulcers with >80% reduction in ulcer size 10 weeks after administration of CACIPLIQ) (P = 0.936). Additionally, there was no statistically significant difference in secondary endpoints, including adverse events. In conclusion, the addition of CACIPLIQ to standard wound care in neuropathic diabetic foot ulcers does not impact wound healing in comparison with the standard wound care
Measurement of damage growth in ultrasonic spot welded joint
No full textUltrasonic spot welding is a joining technique for thermoplastic composites with great potential regarding processing speed and cost. To investigate the damage tolerance and possible inherent damage arresting behavior of multi-spot welded joints, a technique is necessary to measure damage growth in the joints under cyclic loading. Visual inspection is not possible because the damage is not located on the outside surface and conventional techniques such as C-scan are not practical during a fatigue test because the specimen would have to be removed from the setup. This paper details a methodology for quantifying damage growth rates in singlespot welded joints using surface strain measurements made by Digital Image Correlation. This represents the first step towards developing a methodology for quantifying damage progression behavior in complex multi-spot welded joints.Structural Integrity & CompositesAerospace Structures & Computational Mechanic
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