164,396 research outputs found
rizdeology | S2E5: Rodolphe El-Khoury, Hashim Sarkis, Nader Tehrani
No full textOn this episode, I sat down with Rodolphe El-Khoury 86 BArch, Hashim Sarkis 85 BArch, Nader Tehrani 86 BArch. We spoke about how their friendship, formed in the RISD Architecture Department, led them to their current positions as the deans of the University of Miami School of Architecture, MIT School of Architecture and Planning, and The Cooper Union School of Architecture. We were curious if there was a special ingredient at RISD which produced three great leaders. And we even asked if they are interested in becoming the next department head at RISD Architecture... only kidding, of course.
Graphic Design by Aanya Arora, AR \u2724https://digitalcommons.risd.edu/library_rizdeology/1012/thumbnail.jp
T-cell receptor J-beta gene segment usage in immature and mature human thymocytes
No full textImmature double positive (DP, CD4+CD8+) and mature single positive (SP, CD4+CD8- and CD4-CD8+) human thymocytes from nine thymi were analysed for their complete patterns of relative TCR J beta multigene member usage in relation to six rearranged V beta family exons (V beta 5.1, 6.1-3, 8, 9, 12 and 18). Each sample tested contained mRNA transcripts corresponding to all potential V beta(D beta)J beta combinations. Individual J beta gene segments were expressed in a similar, highly non-random manner both in SP and DP thymocytes, irrespective of original genomic position of the individual associated V beta exon. In addition, ranges of family usage and frequency of individual over-representations of J beta gene segments, as determined in DP and SP thymocyte populations, displayed no significant differences. Upon comparison of DP and SP thymocytes, however, a discrepancy in one aspect of J beta gene utilization was established: decreasing J beta family 1/J beta family 2 ratios were determined to be positively correlated with increasing maturity of thymocytes, a condition further supported by data previously obtained from studies of PBL T cells. At the individual J beta gene level, the observed gradual modification of the relative family usage can largely be explained by a significant shift from a higher J beta 1.1/J beta 2.7 ratio in DP to a higher J beta 2.7/J beta 1.1 ratio in SP thymocytes. Altogether, the present results imply that selectional processes in the thymus appear to have only minor consequences on the distribution pattern of expressed J beta exons. Hence, the disproportionate pattern of TCR J beta gene usage seems to be established mainly at the recombinatorial level followed by minor adjustments during thymic and post-thymic events
[Report to Chief J. E. Curry, by an unknown author #1]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
[Report to Chief J. E. Curry, by an unknown author #2]
No full textReport to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
Energy harvesting from train vibrations
No full textIn this paper, linear mechanical oscillators are designed to harvest energy from train-induced vibrations. The harvested energy could be used, for example, to charge sensors mounted on the rail track for structural health monitoring. The dominant frequencies due to a passing train are determined for a specific train and speed from a recorded acceleration time-history. Using a simple model of an oscillator, the total energy harvested for the passage of one train is calculated. The stiffness, and hence the tuning frequency of the device, is varied in simulations to determine the optimum frequency at which to tune the device for a constant value of mass and damping in the device. Further simulations are conducted to investigate the power that could be harvested from multiple oscillators tuned at several dominant frequencies, and their performances are analysed and compared. The constraint for maximum relative displacement is considered in the design of each harvester, and this is adopted to assure that the amplitude of the oscillation is finite and does not exceed the physical size of the device. The robustness of the harvester is also analysed for different train speeds
The Cultural Transmission and Evolution of Folk Narratives
No full textFolk narratives—such as fairy tales, legends, and fables—are products of tradition, rather than individual authors. As they get passed on from person to person and from generation to generation new variants evolve, some of which catch on and generate new traditions, while others soon fade into extinction. Folklorists have long been interested in documenting and reconstructing these processes, but have often been stymied by the limitations of the folklore record. Cultural Evolution has brought powerful new concepts and methods to investigate the transmission histories of folk narratives, from comparative phylogenetic analyses of the relationships among similar tales from different cultures, to experimental studies of how stories mutate and evolve through oral transmission. This chapter reviews these contributions and considers prospects for future research into the cultural evolution of folk narrative traditions
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