1,783 research outputs found
Marion Wallace Correspondence
No full textEntries include the brief biographical information of fifteen year old Miss Marion Wallace on publishing her first volume of poetry written between the ages of nine and fourteen, a letter typed by the Maine State Library introducing Marion Wallace to the Maine Author Collection and requesting a copy of her book for this collection, a handwritten biographical letter of reply from Marion Wallace, and a typed letter of encouragement from the Maine State Library on receipt of her book of poems Stray Thoughts for the Maine Author Collection
Stress during Pregnancy and Offspring Pediatric Disease: A National Cohort Study
No full textBackground: Identifying risk factors for adverse health outcomes in children is important. The intrauterine environment plays a pivotal role for health and disease across life. Objectives: To conduct a comprehensive study to determine whether common psychosocial stress during pregnancy is a risk factor of a wide spectrum of pediatric diseases in the offspring. Methods: The study was conducted in a population-based sample of mothers with live singleton births (N=66203, 71.4% of those eligible) from the Danish National Birth Cohort, using prospective data. We estimated the association between maternal stress during pregnancy (classified based on two a priori defined indicators of common stress forms, life stress and emotional stress) and offspring diseases during childhood (grouped into 16 categories of ICD-10 diagnoses based on data from national registries), controlling for maternal stress after pregnancy. Results: Median age at end of follow-up was 6.2 (3.6-8.9) years. Life stress (highest compared to lowest quartile) was associated with an increased risk of conditions originating in the perinatal period [odds ratio (OR)=1.13; 95% confidence interval (CI)=1.06-1.21] and congenital malformations (OR=1.17; CI=1.06-1.28), and of the first diagnosis of infection [hazard ratio (HR)=1.28; CI=1.17-1.39], mental disorders (age 0-2.5 years: HR=2.03; CI=1.32-3.14), eye (age 0-4.5 years: HR=1.27; CI=1.06-1.53), ear (HR=1.36; CI=1.23-1.51), respiratory (HR=1.27; CI=1.19-1.35), digestive (HR=1.23; CI=1.11-1.37), skin (HR=1.24; CI=1.09-1.43), musculoskeletal (HR=1.15; CI=1.01-1.30), and genitourinary diseases (HR=1.25; CI=1.08-1.45). Emotional stress was associated with an increased risk for the first diagnosis of infection (HR=1.09; CI=1.01-1.18) and a decreased risk for the first diagnosis of endocrine (HR=0.81; CI=0.67-0.99), eye (HR=0.84; CI=0.71-0.99), and circulatory diseases (age 0-3 years: HR=0.63; CI=0.42-0.95). Conclusions: Maternal life stress during pregnancy be a common risk factor for impaired child health. The results suggest new approaches to reduce childhood diseases
Ecological energetics of Eudyptes penguins at Marion Island
No full textIncludes bibliographies.Macaroni Penguins (Eudyptes chrysolophus) and Rockhopper Penguins (E. chrysocome) breed sympatrically at Marion Island in the sub-Antarctic, where they account for a substantial proportion of the avian biomass breeding at the island. This thesis documents the energy requirements of the two species during their respective breeding and moulting cycles at the island. Resting metabolic rates, calculated from lowest, stable rates of oxygen consumption over 24 h, averaged 25 % greater than basal metabolic rates predicted from allometric equations. Body temperatures of the penguins and the relationships between metabolic rates and temperature were investigated over a range of -10°C to 25°C. Lower critical temperature of Rockhopper Penguins was between 0°C and 5°C, but that of Macaroni Penguins could not be clearly ascertained. Measured metabolic rates of other species of penguins are reviewed and intra- and inter-specific differences in metabolic rates are discussed. In contrast to most penguins measured, individuals maintained in zoos or held in captivity for long periods had metabolic rates lower than predicted basal levels
Deadly physical force plan - Marion County
No full textDeadly force plan -- Roster of Planning Authority members -- Exhibits/Appendices (Including agency specific deadly force guidelines -- Attorney General's plan approval.Title from PDF cover (viewed on December 7, 2020).Separate documents compiled into one report by the State Library of Oregon.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Marion Irwin
No full textPhotograph - Joe Irwin's mother Marion (left) and her sister Mag. Vulcan, Albert
Marion Irwin - 02
No full textPhotograph - Joe Irwin's mother Marion (left) and her sister Mag. Vulcan, Albert
Dedication of Marion Roger Park Program
No full textProgram - Dedication of Marion Rogers Park - July 20, 198
Sherry Crawford, Debbie Rotolo, and Marion Sell Oral History Interview
No full textDuring the tenure of Tampa Mayor Sandy Freedman (1986-1995), Sherry Crawford, Debbie Rotolo, and Marion Sell all served as executive aides in the mayor\u27s office. Some of the topics they discuss include the mayor\u27s Model Cities Program, the United Way, Paint Your Heart Out, and downtown development issues. The interview ends with a discussion of various visiting dignitaries including Al Gore, Queen Elizabeth II, Richard Simmons, Bill Clinton, and author James Michener
Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review
No full textBACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids. Structural and functional alterations resulting from such changes may persist throughout life and have been associated with diverse diseases. One system that could be particularly sensitive to fetal glucocorticoid overexposure is the hypothalamic-pituitary-adrenal (hpa) axis. Many human studies have investigated this possibility, but a systematic review to identify consistent, emergent findings is lacking. METHODS: We systematically review 49 human studies, assessing the effects of intrauterine exposure to synthetic glucocorticoids on fetal, neonate, and infant hpa function. RESULTS: Study quality varied considerably, but the main findings held true after restricting the analyses to higher-quality studies: intrauterine exposure to synthetic glucocorticoids reduces offspring hpa activity under unstimulated conditions after pain but not pharmacological challenge. Although reduced unstimulated hpa function appears to recover within the first 2 wk postpartum, blunted hpa reactivity to pain is likely to persist throughout the first 4 months of life. There is some evidence that the magnitude of the effects is correlated with the total amount of glucocorticoids administered and varies with the time interval between glucocorticoid exposure and hpa assessment. CONCLUSIONS: This systematic review has allowed the demonstration of the way in which intrauterine exposure to various regimens of synthetic glucocorticoids affects various forms of hpa function. As such, it guides future studies in terms of which variables need to be focused on in order to further strengthen the understanding of such therapy, whilst continuing to profit from its clinical benefits
Cortisol awakening response in infants during the first six postnatal months and its relation to birth outcome
No full textContext: The rise of cortisol concentrations after awakening is well documented in adults and children and commonly used as easily accessible marker of hypothalamic-pituitary-adrenal (HPA) reactivity.
Objective: The purpose of this study was to demonstrate the existence of a salivary cortisol awakening response (CAR) in infants, and to estimate its association with birth outcome.
Setting: The study was conducted in the general community.
Participants: Healthy infants up to six months age (N=64).
Main outcome measures: Mothers were instructed to collect their infant’s saliva immediately and 30 min after awakening on two days within 45 days, irrespective of awakening time. Information on birth outcome was collected from medical records and questionnaires.
Results: Linear mixed models analysis revealed a significant rise of infant salivary cortisol concentrations within 30 minutes after awakening (b=0.128, SE=0.024, t61=5.31, p<0.001), which was quite stable across the two sampling days (r=0.40, p=0.002). The infant CAR was predicted by length of gestation (t61=2.43, p=0.018).
Conclusions: The current data demonstrate the existence of a CAR in infants as early as during the first six postnatal months; its relationship with length of gestation supports its usefulness for questions related to developmental neuroscience. Therefore, the infant CAR emerges as non-invasive biomarker of HPA axis dynamics at this early stage of life, with relevance for future research and potential clinical applications
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