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    Cryptic diversity within the Megophrys major species group (Amphibia: Megophryidae) of the Asian Horned Frogs: Phylogenetic perspectives and a taxonomic revision of South Asian taxa, with descriptions of four new species

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    Mahony, Stephen, Kamei, Rachunliu G., Teeling, Emma C. (2018): Cryptic diversity within the Megophrys major species group (Amphibia: Megophryidae) of the Asian Horned Frogs: Phylogenetic perspectives and a taxonomic revision of South Asian taxa, with descriptions of four new species. Zootaxa 4523 (1): 1-96, DOI: 10.11646/zootaxa.4523.1.

    Three new species of horned frogs, Megophrys (Amphibia: Megophryidae), from northeast India, with a resolution to the identity of Megophrys boettgeri populations reported from the region

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    Mahony, Stephen, Teeling, Emma C., Biju, S. D. (2013): Three new species of horned frogs, Megophrys (Amphibia: Megophryidae), from northeast India, with a resolution to the identity of Megophrys boettgeri populations reported from the region. Zootaxa 3722 (2): 143-169, DOI: 10.11646/zootaxa.3722.2.

    Figure 11 in Taxonomic review of the Asian Horned Frogs (Amphibia: Megophrys Kuhl & Van Hasselt) of Northeast India and Bangladesh previously misidentified as M. parva (Boulenger), with descriptions of three new species

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    Figure 11. Megophrys numhbumaeng sp. nov. adult male type specimens from Tamenglong district, Manipur state, India: (a–b). holotype (BNHS 6075: SVL 34.6 mm) in life; (a). dorsolateral view; (b). ventral view; (c–d). paratype (BNHS 6076: SVL 33.8 mm) in preservation: (c). dorsal view; (d). ventral view.Published as part of Mahony, Stephen, Kamei, Rachunliu G., Teeling, Emma C. & Biju, S. D., 2020, Taxonomic review of the Asian Horned Frogs (Amphibia: Megophrys Kuhl & Van Hasselt) of Northeast India and Bangladesh previously misidentified as M. parva (Boulenger), with descriptions of three new species, pp. 119-194 in Journal of Natural History 54 (1-4) on page 159, DOI: 10.1080/00222933.2020.1736679, http://zenodo.org/record/460889

    Megophrys (Xenophrys) major Mahony & Kamei & Teeling 2018, s.s.

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    Megophrys (Xenophrys) major s.s. Boulenger, 1908 (Figures 14 & 15; Table 1) Xenophrys gigas Jerdon 1870:85 (partim: Khasi Hills). In: Notes on Indian herpetology. Proceedings of the Asiatic Society of Bengal, March, 1870: 66–85. Megalophrys major Boulenger 1908:410, 416, Pl. xxiii. In: A revision of the oriental pelobatid batrachians (genus Megalophrys). Proceedings of the Zoological Society of London, 1908: 407–430 + Pl. xxii–xxv + fig. 71.Published as part of Mahony, Stephen, Kamei, Rachunliu G. & Teeling, Emma C., 2018, Cryptic diversity within the Megophrys major species group (Amphibia: Megophryidae) of the Asian Horned Frogs: Phylogenetic perspectives and a taxonomic revision of South Asian taxa, with descriptions of four new species, pp. 1-96 in Zootaxa 4523 (1) on page 39, DOI: 10.11646/zootaxa.4523.1.1, http://zenodo.org/record/261020

    FIGURE 4. A–D in Three new species of horned frogs, Megophrys (Amphibia: Megophryidae), from northeast India, with a resolution to the identity of Megophrys boettgeri populations reported from the region

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    FIGURE 4. A–D. Habitat images at the collection localities of the three new species: A. for Megophrys vegrandis sp. nov. showing the point where the side stream meets the Sessa river (dark opening in vegetation, centre frame on the bank of the river), B. for Megophrys oropedion sp. nov. showing the type locality showing Um Risa stream, in Malki Forest, C. for Megophrys oropedion sp. nov. showing a collection stream in Mawphlang Sacred Forest, D. for Megophrys ancrae sp. nov. showing the stream at the type locality in Deban, Namdapha National Park and Tiger Reserve.Published as part of Mahony, Stephen, Teeling, Emma C. & Biju, S. D., 2013, Three new species of horned frogs, Megophrys (Amphibia: Megophryidae), from northeast India, with a resolution to the identity of Megophrys boettgeri populations reported from the region, pp. 143-169 in Zootaxa 3722 (2) on page 150, DOI: 10.11646/zootaxa.3722.2.2, http://zenodo.org/record/24932

    FIGURE 21 in Cryptic diversity within the Megophrys major species group (Amphibia: Megophryidae) of the Asian Horned Frogs: Phylogenetic perspectives and a taxonomic revision of South Asian taxa, with descriptions of four new species

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    FIGURE 21. Megophrys himalayana sp. nov.: A. dorsolateral view of adult male holotype (BNHS 6050: SVL 72.1 mm) in life; B. dorsolateral view of adult female referred specimen (SDBDU 2009.750: SVL 83.9 mm) in life; C–D. dorsolateral views of adult male paratype (BNHS 6051: SVL 70.2 mm) in life; E. dorsolateral view of adult male referred specimen (SDBDU 2009.787: SVL 70.2 mm) in life; F. ventral view of two adult males (left paratype BNHS 6051: SVL 70.2 mm; right holotype BNHS 6050: SVL 72.1 mm) immediately after euthanisation; G. ventral view of adult referred specimens in preservation, left male (SDBDU 2009.787: SVL 70.2 mm), right female (SDBDU 2009.750: SVL 83.9 mm); H. variation in ventral markings of adult male holotype and paratypes in preservation, clockwise from the top left specimen (BNHS 6050: SVL 72.1 mm; BNHS 6052: SVL 68.5 mm; BNHS 6054: SVL 68.0 mm; BNHS 6053: SVL 73.5 mm; BNHS 6051: SVL 70.2 mm).Published as part of Mahony, Stephen, Kamei, Rachunliu G. & Teeling, Emma C., 2018, Cryptic diversity within the Megophrys major species group (Amphibia: Megophryidae) of the Asian Horned Frogs: Phylogenetic perspectives and a taxonomic revision of South Asian taxa, with descriptions of four new species, pp. 1-96 in Zootaxa 4523 (1) on page 56, DOI: 10.11646/zootaxa.4523.1.1, http://zenodo.org/record/261020

    FIG. 5 in How and Why Overcome the Impediments to Resolution: Lessons from rhinolophid and hipposiderid Bats

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    FIG. 5. LTT plot showing the diversification rate of the genera Rhinolophus and Hipposideros for Cyt b and Cox1, where time is represented by arbitrary values with 0.0 representing the present.Published as part of Foley, Nicole M., Thong, Vu Dinh, Soisook, Pipat, Goodman, Steven M., Armstrong, Kyle N., Jacobs, David S., Puechmaille, Sebastien J. & Teeling, Emma C., 2014, How and Why Overcome the Impediments to Resolution: Lessons from rhinolophid and hipposiderid Bats, pp. 313-333 in Molecular Biology and Evolution 32 (2) on page 322, DOI: 10.1093/molbev/msu329, http://zenodo.org/record/376049

    FIG. 6 in How and Why Overcome the Impediments to Resolution: Lessons from rhinolophid and hipposiderid Bats

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    FIG. 6. Showing the relative difference in nodal support between intron and jack-knifed exon data sets of equal size, where colored dots indicate the proportion by which nodes are better resolved by either intron (red) or exon (green) data for (a) intron topology and (b) the exon topology. Species names are as in figure 2.Published as part of Foley, Nicole M., Thong, Vu Dinh, Soisook, Pipat, Goodman, Steven M., Armstrong, Kyle N., Jacobs, David S., Puechmaille, Sebastien J. & Teeling, Emma C., 2014, How and Why Overcome the Impediments to Resolution: Lessons from rhinolophid and hipposiderid Bats, pp. 313-333 in Molecular Biology and Evolution 32 (2) on page 323, DOI: 10.1093/molbev/msu329, http://zenodo.org/record/376049

    The predictable network topology of evolutionary genomic constraint

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    Large-scale comparative genomics studies offer valuable resources for understanding both functional and evolutionary rate constraints. It is suggested that constraint aligns with the topology of genomic networks, increasing towards the center, with intermediate nodes combining relaxed constraint with higher contributions to the phenotype due to pleiotropy. However, this pattern has yet to be demonstrated in vertebrates. This study shows that constraint intensifies towards the network's center in placental mammals. Genes with rate changes associated with emergence of hibernation cluster mostly towards intermediate positions, with higher constraint in faster-evolving genes, which is indicative of a "sweet spot" for adaptation. If this trend holds universally, network node metrics could predict high-constraint regions even in clades lacking empirical constraint data.European Commissio

    FIG. 1. Myotis myotis and M in A potent anti-inflammatory response in bat macrophages may be linked to extended longevity and viral tolerance

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    FIG. 1. Myotis myotis and M. musculus macrophages present differential response to LPS and Poly(I:C) challenge. Change in gene expression of A — IFN-β, B — IL-1β, C — TNF, D — Il-10 in response to LPS and Poly(I:C) treatment at 1, 4 and 24 hr time points are presented as changes in delta Ct values normalized to actin-β. Ratios of the fold induction of anti-inflammatory Il-10 to proinflammatory TNF (E) and Il-1β (F) are also presented. G — Literature derived Il-10/TNF ratios for other mammals. H — NO generated by stimulated M. myotis and mouse macrophages. Bars represent the mean of two experimental repeats ± SEM. Presented P -values indicate the significance of the difference between species from analysis of variance (ANOVA)Published as part of Kacprzyk, Joanna, Hughes, Graham M., Palsson-Mcdermott, Eva M., Quinn, Susan R., Puechmaille, Sébastien J., O'Neill, Luke A. J. & Teeling, Emma C., 2017, A potent anti-inflammatory response in bat macrophages may be linked to extended longevity and viral tolerance, pp. 219-228 in Acta Chiropterologica 19 (2) on page 223, DOI: 10.3161/15081109ACC2017.19.2.001, http://zenodo.org/record/784119
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