1,721,048 research outputs found
Use of Xpert MTB/RIF Ultra assays among paediatric tuberculosis experts in Europe - Supplementary table
No full textSupplementary table showing participating centres for the Letter to the Editor 'Use of Xpert MTB/RIF Ultra assays among paediatric tuberculosis experts in Europe', by Paola Villanueva, Olaf Neth, Nicole Ritz and Marc Tebruegge of the Paediatric Tuberculosis Network European Trials Group, submitted to the European Respiratory Journal.</span
Images in HIV/AIDS. Stevens-Johnson syndrome associated with thalidomide treatment in HIV infection
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Enterovirus infections in neonates
No full textEnteroviruses, which include echoviruses, coxsackie A and B viruses, polioviruses and the ‘numbered’ enteroviruses, are among the most common viruses causing disease in humans. A large proportion of enteroviral infections occur in neonates and infants. There is a wide spectrum of clinical manifestations that can be caused by enterovirusinfection with varying degrees of severity. In the neonatal age group, enteroviral infections are associated with significant morbidity and mortality, particularly when infection occurs antenatally. This review provides a detailed overview of the epidemiology and clinical features of enterovirusinfections in the neonatal period. In addition, laboratory features and diagnostic investigations are discussed. A review of the currently available data for prophylactic and therapeutic interventions, including antiviral therapy, is also presente
Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis
No full textRecurrent bacterial meningitis is a rare phenomenon and generally poses a considerable diagnostic challenge to the clinician. Ultimately, a structured approach and early diagnosis of any underlying pathology are crucial to prevent further episodes and improve the overall outcome for the affected individual. In this article, we are reviewing the existing literature on this topic over the last two decades, encompassing 363 cases of recurrent bacterial meningitis described in 144 publications. Of these cases, 214 (59%) were related to anatomical problems, 132 (36%) were related to immunodeficiencies, and 17 (5%) were related to parameningeal infections. The review includes a detailed discussion of the underlying pathologies and microbiological aspects as well as recommendations for appropriate diagnostic pathways for investigating this unusual entity
Adenovirus infection in the immunocompromised host
No full textThere are 51 known serotypes of human adenovirus, which are divided into subgroups (or species) A to F Table ). An additional serotype (52), which potentially constitutes a new species (G), has recently been reported after genomic sequencing and phylogenetic analysis of an isolate in the U.S
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