355 research outputs found
Structures of the conformational isomers and polymorph modifications of N-substituted 2,6-(E,E)-bis(ferrocenylidene)piperid-4-ones: photo- and electrochemically induced E/Z isomerization
No full textFour N-substituted 2,6-(E,E)-bis(ferrocenylidene)piperid-4-ones (NH 1, NMe 2, NEt 3, NCH2Ph 4) were prepared by aldol condensation between ferrocenecarbaldehyde and two equivalents of N-substituted piperid-4-ones with high yields. The N-protonated compounds were obtained by reaction with HBF4·Et2O acid. The molecular structures of compounds 2, 3, 2·HBF4 and 4·HBF4 were confirmed by X-ray diffraction analysis and three types of conformational isomers were elucidated. Two polymorph modifications were found for compound 2·HBF4. The electron transfer properties of the complexes were examined by electrochemical and spectroelectrochemical techniques. Complexes 1-4 undergo a reversible process of two-electron oxidation and partially reversible one-electron reduction. The photo- and electrochemically induced E/Z isomerisation of the complexes was monitored by UV-vis and 1H NMR spectroscopy
Foreign Prison Experience Resocialization of Prisoners
Get PDFAt the present stage, the analysis of foreign experience in the field of re-socialization of prisoners becomes relevant. One of the main objectives of this article is to consider the problem of the process of re-socialization of prisoners. Among the objectives of this article is to analyze the best foreign experience in this field. The author pays special attention to various types of social, psychological and pedagogical work with prisoners. As a result, the author analyzes modern social and psychological programs for prisoners, contributing to their successful re-socialization. In the process of writing the article used General scientific and private scientific research methods. The leading method of studying this problem is comparative analysis. The result of the analysis was a generalization of the author of the advanced methods of foreign practices in the field of the re-socialization significance of the results is confirmed by isolation of the author of the directions in the process of re-socialization of prisoners, which can be applied as best practices in the activities of the UIS Russia
The Manifestation of the Psychologist's Professional Identity in the Characteristics of the Communicative and Gendered 'Me'
No full textProblems of choosing optimal solutions for systems with random and non-random perturbations
Get PDFThe problem of choosing an optimal solution in stochastic optimization problem containing both random perturbations with given distributions and nonrandom perturbations about which only the regions of their possible values are known. As a criterion of optimality, the quantile criterion is used, i.e. The objective function value guaranteed with some given probability is optimised. This problem is closely connected with the problem of the construction confidence estimates for a statistically uncertain random vector that is a random vector with an incompletely known distribution. A concept of the generalized confidence set is used for statistically uncertain vector, and its properties are studied. The quantile stochastic optimization problem under incomplete information is solved by means of an optimal choice of the generalized confidence region. © 2017 Author(s)
Caracterización del ganglio linfático centinela para determinar la presencia de micro-metástasis
Get PDFilustraciones, diagramasEl ganglio linfático centinela es un predictor de agresividad del cáncer de mama. El índice de riesgos instantáneos informado fue de 2,14, intervalo de confianza del 95%, lo que muestra que los pacientes con micrometástasis (MM) tienen una mayor probabilidad de una peor supervivencia libre de enfermedad (SSE) y supervivencia general (SG) en comparación con aquellos que tienen ganglios. negativos, la detección temprana del análisis de micrometástasis parece ser el enfoque más ventajoso para los pacientes. Este trabajo propone una detección automática de micrometástasis mediante la cuantificación de cambios celulares locales. La estrategia propuesta caracteriza la morfometría, el color y la textura de los núcleos para establecer diferencias entre MM y el tejido normal. El modelo de color se obtiene del plano [(r − b), g] mientras que la textura corresponde a las características de Haralick de cinco órdenes diferentes de la matriz de coocurrencia. (Texto tomado de la fuente)The sentinel lymph node is a predictor of breast cancer aggressiveness. The hazard ratio
reported was 2.14, 95% confidence interval, which shows that the patient with micro-metastasis
(MM) have a higher probability of poorer Disease-free survival (DFS) and overall survival
(OS) Relative to those who are node-negative, early detection of micro-metastasis
analysis appears to be the approach most advantageous for patients. This work proposes an
automatic detection of micro-metastasis by quantifying local cellular changes. The proposed
strategy characterizes nuclei morphometry, color, and texture to establish differences between
MM and normal tissue. The color model is obtained from the plane [(r − b), g] while texture
corresponds to Haralick’s features from five different orders of the co-occurrence matrix.
This description is complemented by the cellular area obtained from a conventional watershed
segmentation.MaestríaModelamiento y análisis de datos basados en técnicas de machine learning.Procesamiento de ImágenesPatología Digita
Polymorphism rs2383207 of CDKN2B-AS and Susceptibility to Atherosclerosis: A Mini Review
No full textWe conducted this meta-analysis to estimate associations between CDKN2B antisense (CDKN2B-AS) rs2383207 polymorphism and susceptibility to atherosclerosis. A systematic literature research of Google Scholar and PubMed was performed to identify eligible studies. Overall, eight studies were included for meta-analyses. The association was assessed by statistical odds’ ratio (OR) with 95% confidence interval (CI). RevMan software (Cochrane Collaboration, 5.3. Copenhagen) was used for the meta-analysis. Pooled overall analyses showed that rs2383207 polymorphism was associated with the risk of atherosclerosis in the whole population. Additional analyses by ethnicity revealed that rs2383207 polymorphism was associated with susceptibility to atherosclerosis in Asians and Caucasians. Our results suggest that rs2383207, might serve as genetic biomarkers of atherosclerosis. Further, studies will be required to confirm the observed association
Caracterización del ganglio linfático centinela para determinar la presencia de micro-metástasis
Get PDFilustraciones, diagramasEl ganglio linfático centinela es un predictor de agresividad del cáncer de mama. El índice de riesgos instantáneos informado fue de 2,14, intervalo de confianza del 95%, lo que muestra que los pacientes con micrometástasis (MM) tienen una mayor probabilidad de una peor supervivencia libre de enfermedad (SSE) y supervivencia general (SG) en comparación con aquellos que tienen ganglios. negativos, la detección temprana del análisis de micrometástasis parece ser el enfoque más ventajoso para los pacientes. Este trabajo propone una detección automática de micrometástasis mediante la cuantificación de cambios celulares locales. La estrategia propuesta caracteriza la morfometría, el color y la textura de los núcleos para establecer diferencias entre MM y el tejido normal. El modelo de color se obtiene del plano [(r − b), g] mientras que la textura corresponde a las características de Haralick de cinco órdenes diferentes de la matriz de coocurrencia. (Texto tomado de la fuente)The sentinel lymph node is a predictor of breast cancer aggressiveness. The hazard ratio
reported was 2.14, 95% confidence interval, which shows that the patient with micro-metastasis
(MM) have a higher probability of poorer Disease-free survival (DFS) and overall survival
(OS) Relative to those who are node-negative, early detection of micro-metastasis
analysis appears to be the approach most advantageous for patients. This work proposes an
automatic detection of micro-metastasis by quantifying local cellular changes. The proposed
strategy characterizes nuclei morphometry, color, and texture to establish differences between
MM and normal tissue. The color model is obtained from the plane [(r − b), g] while texture
corresponds to Haralick’s features from five different orders of the co-occurrence matrix.
This description is complemented by the cellular area obtained from a conventional watershed
segmentation.MaestríaModelamiento y análisis de datos basados en técnicas de machine learning.Procesamiento de ImágenesPatología Digita
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