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Letter from A.L. Monmerqué de Courmont.
No full textLetter from A.L. Monmerqué de Courmont, possibly Adélaïde Louise de Monmerqué (1767-1835) who had been married to Louis Marie Le Bas de Courmont (1741-1794), dated 10 pluvoise. It is not addressed but was presumably sent to Philippe-Antoine Merlin, as it comprises the verso of one of his requisitions from 1802. In this letter the author requests a day and an hour when she (or he) might meet with the recipient
Soluble ST2, a modulator of the inflammatory response, in preterm and term labor
No full textOBJECTIVE:
Intra-amniotic infection/inflammation (IAI) is causally linked with spontaneous preterm labor and delivery. The ST2L receptor and its soluble form (sST2) are capable of binding to interleukin (IL)-33, a member of the IL-1 superfamily. Members of this cytokine family have been implicated in the onset of spontaneous preterm labor in the context of infection. Soluble ST2 has anti-inflammatory properties, and plasma concentrations are elevated in systemic inflammation, such as sepsis, acute pyelonephritis in pregnancy and the fetal inflammatory response syndrome. The aims of this study were to examine: (1) whether amniotic fluid concentrations of sST2 change with IAI, preterm, and term parturition; and (2) if mRNA expression of ST2 in the chorioamniotic membranes changes with acute histologic chorioamnionitis in women who deliver preterm.
METHOD:
A cross-sectional study was conducted to determine amniotic fluid concentrations of sST2 in: (1) women with preterm labor (PTL) who delivered at term (n=49); (2) women with PTL who delivered preterm without IAI (n=21); (3) women with PTL who delivered preterm with IAI (n=31); (4) term pregnancies not in labor (n=13); and (5) term pregnancies in labor (n=43). The amniotic fluid concentration of sST2 was determined by ELISA. The mRNA expression of ST2 in the chorioamniotic membranes of women who delivered preterm with (n=24), and without acute histologic chorioamnionitis (n=19) was determined by qRT-PCR.
RESULTS:
(1) Patients with PTL who delivered preterm with IAI had a lower median amniotic fluid concentration of sST2 compared to those with PTL who delivered preterm without IAI [median 410 ng/mL, inter-quartile range (IQR) 152-699 ng/mL versus median 825 ng/mL, IQR 493-1216 ng/mL; p=0.0003] and those with PTL who delivered at term [median 410 ng/mL, IQR 152-699 ng/mL versus median 673 ng/mL, IQR 468-1045 ng/mL; p=0.0003]; (2) no significant differences in the median amniotic fluid concentration of sST2 were observed between patients with PTL who delivered at term and those who delivered preterm without IAI (p=0.4), and between women at term in labor and those at term not in labor (p=0.9); (3) the mean mRNA expression of ST2 was 4-fold lower in women who delivered preterm with acute histologic chorioamnionitis than in those without this lesion (p=0.008).
CONCLUSIONS:
The median sST2 amniotic fluid concentration and mRNA expression of ST2 by chorioamniotic membranes is lower in PTL associated with IAI and acute histologic chorioamnionitis than in PTL without these conditions. Changes in the median amniotic fluid sST2 concentration are not observed in preterm and term parturition without IAI. Thus, amniotic fluid sST2 in the presence of IAI behaves differently when compared to sST2 in the plasma of individuals affected by fetal inflammatory response syndrome, acute pyelonephritis in pregnancy, and adult sepsis. Decreased concentrations of sST2 in IAI are likely to promote a pro-inflammatory response, which is important for parturition in the context of infection
S.L.I.M., a small linear interdependent model of eight EU-member states, the USA and Japan
No full textInternational Economics;EU
A Review of Some Updates in the 13th Edition of “Sears and Zemansky’s University Physics with Modern Physics” (Authors: Hugh D. Young and Roger A. Freedman; contributing author, A. Lewis Ford; 2012)
No full textYoung, H.D.; and Freedman, R.A.; Ford, A.L. (contributing author). 2012. Sears and Zemansky’s University Physics with Modern Physics. 13th ed.Pearson Education, Inc., Addison-Wesley, San Francisco, CA, USA
Absorption refrigeration machines: Theoretical and experimental assessment of the performance of aqua-ammonia absorption machines operated at marginal conditions, e.g. when powered by solar or waste heat. Development of a new type of absorber.
No full textMechanical, Maritime and Materials EngineeringMechanical, Maritime and Materials Engineerin
Development of an advanced absorption heat transformer
No full textMechanical Maritime and Materials Engineerin
Thermal energy storage by means of an absorption cycle
No full textMechanical Maritime and Materials Engineerin
Modelling of a refrigerating system coupled with a refridgerated room
No full textMechanical Maritime and Materials Engineerin
Detecting spatial and temporal house price diffusion in the Netherlands: A Bayesian network approach
No full textFollowing the 2007–08 Global Financial Crisis, there has been a growing research interest on the spatial interrelationships between house prices in many countries. This paper examines the spatio-temporal relationship between house prices in the twelve provinces of the Netherlands using a recently proposed econometric modelling technique called the Bayesian Graphical Vector Autoregression (BG-VAR). This network approach is suitable for analysing the complex spatial interactions between house prices. It enables a data-driven identification of the most dominant provinces where temporal house price shocks may largely diffuse through the housing market. Using temporal house price volatilities for owner-occupied dwellings from 1995Q1 to 2016Q1, the results show evidence of temporal dependence and house price diffusion patterns in distinct sub-periods from different provincial housing sub-markets in the Netherlands. In particular, the results indicate that Noord-Holland was most predominant from 1995Q1 to 2005Q2, while Drenthe became most central in the period 2005Q3–2016Q1.Accepted Author ManuscriptOLD Housing System
Compact heat and mass exchangers of the plate fin type in thermal sorption systems
No full textMechanical Maritime and Materials Engineerin
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