763 research outputs found

    Supplemental Materials for AJP-GI (ID: GI-00273-2023R1)

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    Journal title: AJP-Gastrointest Liver PhysiolManuscript Title: N-glycosylation of SCAP exacerbates hepatocellular inflammation and lipid accumulation via ACSS2-mediated histone H3K27 acetylation (ID: GI-00273-2023R1)Authors: Xuemei Li, Xiaoqin Tang, Yue Xiang, Zhibo Zhao, Yanping Li, Qiuying Ding, Linkun Zhang, Jingyuan Xu, Lei Zhao, Yao Chen.</p

    Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging

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    Tang, Xuemei, Zhao, Meiyan, Chen, Zhiting, Huang, Jianxiang, Chen, Yan, Wang, Fuhua, Wan, Kai (2021): Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging. Phytochemistry (112930) 192: 1-7, DOI: 10.1016/j.phytochem.2021.112930, URL: http://dx.doi.org/10.1016/j.phytochem.2021.11293

    Fig. 3 in Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging

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    Fig. 3. MALDI-MS spectrum of C. lansium fruit extract in positive ion mode.Published as part of Tang, Xuemei, Zhao, Meiyan, Chen, Zhiting, Huang, Jianxiang, Chen, Yan, Wang, Fuhua & Wan, Kai, 2021, Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging, pp. 1-7 in Phytochemistry (112930) 192 on page 3, DOI: 10.1016/j.phytochem.2021.112930, http://zenodo.org/record/825714

    Fig. 4 in Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging

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    Fig. 4. Distribution of the main alkaloids in diverse tissue parts in the plant of C. lansium. All the MSI were acquired in positive ion mode. The number of pixels in x and y axis was 243 × 248 for the fruit, and 100 × 70 for the stem and 65 × 37 for the leaf parts. The distributions are displayed as heat maps, with the color code between black (low) and red (high). Images were exported from the Shimadzu Imaging software. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)Published as part of Tang, Xuemei, Zhao, Meiyan, Chen, Zhiting, Huang, Jianxiang, Chen, Yan, Wang, Fuhua & Wan, Kai, 2021, Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging, pp. 1-7 in Phytochemistry (112930) 192 on page 5, DOI: 10.1016/j.phytochem.2021.112930, http://zenodo.org/record/825714

    Fig. 2 in Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging

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    Fig. 2. Comparison of sample pretreatment methods for MALDI-MSI analysis. (A) Intensities of ion peaks corresponding to organic acids, sugars, and alkaloids in the three different sections using airbrush, iMLayer or combined methods for matrix application. Data represent the mean ± SE of intensities of ions at m/z 230.9, 381.0, 264.1 and 367.1 (n = 3), respectively. Photographs of DHB matrix material prepared by different methods: (B) Spray by airbrush, (C) Sublimation by iMLayer, (D) Spray after sublimation. Films and crystals observation were recorded under the light microscope (× 40).Published as part of Tang, Xuemei, Zhao, Meiyan, Chen, Zhiting, Huang, Jianxiang, Chen, Yan, Wang, Fuhua & Wan, Kai, 2021, Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging, pp. 1-7 in Phytochemistry (112930) 192 on page 3, DOI: 10.1016/j.phytochem.2021.112930, http://zenodo.org/record/825714

    Fig. 5 in Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging

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    Fig. 5. Distribution of the main coumarins in diverse tissue parts in the plant of C. lansium. All the MSI were acquired in positive ion mode. The number of pixels in x and y axis was 243 × 248 for the fruit, and 100 × 70 for the stem and 65 × 37 for the leaf parts. The distributions are displayed as heat maps, with the color code between black (low) and red (high). Images were exported from the Shimadzu Imaging software. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)Published as part of Tang, Xuemei, Zhao, Meiyan, Chen, Zhiting, Huang, Jianxiang, Chen, Yan, Wang, Fuhua & Wan, Kai, 2021, Visualizing the spatial distribution of metabolites in Clausena lansium (Lour.) skeels using matrix-assisted laser desorption/ionization mass spectrometry imaging, pp. 1-7 in Phytochemistry (112930) 192 on page 5, DOI: 10.1016/j.phytochem.2021.112930, http://zenodo.org/record/825714

    A dielectric-barrier discharge enhanced plasma brush array at atmospheric pressure

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    This study developed a large volume cold atmospheric plasma brush array, which was enhanced by a dielectric barrier discharge by integrating a pair of DC glow discharge in parallel. A platinum sheet electrode was placed in the middle of the discharge chamber, which effectively reduced the breakdown voltage and working voltage. Emission spectroscopy diagnosis indicated that many excited argon atoms were distributed almost symmetrically in the lateral direction of the plasma. The concentration variations of reactive species relative to the gas flow rate and discharge current were also examined. (C) 2013 AIP Publishing LLC

    Chitosan and chitooligosaccharide regulated reactive oxygen species homeostasis at wounds of pear fruit during healing

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    Both chitosan (CTS) and chitooligosaccharide (COS) can promote fruit healing. However, whether the two chemicals regulate reactive oxygen species (ROS) homeostasis during wound healing of pear fruit remains unknown. In this study, the wounded pear fruit (Pyrus bretschneideri cv. Dongguo) was treated with a 1 g L-1 CTS and COS. We found CTS and COS treatments increased NADPH oxidase and superoxide dismutase activities, and promoted O2.- and H2O2 production at wounds. CTS and COS also enhanced the activities of catalase, peroxidase, ascorbate peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase, and glutathione reductase, and elevated the levels of ascorbic acid and glutathione. In addition, the two chemicals improved antioxidant capacity in vitro and maintained cell membrane integrity at fruit wounds during healing. Taken together, CTS and COS can regulate ROS homeostasis at wounds of pear fruit during healing by scavenging excessive H2O2 and improving antioxidant capacity. Overall, the COS demonstrated superior performance over the CTS

    Slowing Down DNA Translocation Through Solid-State Nanopores by Pressure

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    The effect of applied pressure on event duration distributions in 3 kb dsDNA translocation is systematically investigated. The effects of pressure magnitude and nanopore size on the length discrimination between 615 bp and 1.14 kbp dsDNA is studied. The pressure-controlled DNA translocation in solid-state nanopores makes a significant contribution to improve the temporal resolution in DNA single-molecule detection.Copyright ? 2013 WILEY-VCH Verlag GmbH &amp; Co. KGaA, Weinheim.Chemistry, MultidisciplinaryChemistry, PhysicalNanoscience &amp; NanotechnologyMaterials Science, MultidisciplinaryPhysics, AppliedPhysics, Condensed MatterSCI(E)EIPubMed8ARTICLE244112-4117
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