69 research outputs found
The effect of enhanced recovery after minimally invasive esophagectomy: a randomized controlled trial
No full textBACKGROUND: The purpose of this randomized controlled trial was to determine if enhanced recovery after surgery (ERAS) would improve outcomes for three-stage minimally invasive esophagectomy (MIE). METHODS: Patients with esophageal cancer undergoing MIE between March 2016 and August 2018 were consecutively enrolled, and were randomly divided into 2 groups: ERAS+group that received a guideline-based ERAS protocol, and ERAS- group that received standard care. The primary endpoint was morbidity after MIE. The secondary endpoints were the length of stay (LOS) and time to ambulation after the surgery. The perioperative results including the Surgical Apgar Score (SAS) and Visualized Analgesia Score (VAS) were also collected and compared. RESULTS: A total of 60 patients in the ERAS+ group and 58 patients in the ERAS- group were included. Postoperatively, lower morbidity and pulmonary complication rate were recorded in the ERAS+ group (33.3% vs. 51.7%; p = 0.04, 16.7% vs. 32.8%; p = 0.04), while the incidence of anastomotic leakage remained comparable (11.7% vs. 15.5%; p = 0.54). There was an earlier ambulation (3 [2–3] days vs. 3 [3–4] days, p = 0.001), but comparable LOS (10 [9–11.25] days vs. 10 [9–13] days; p = 0.165) recorded in ERAS+ group. The ERAS protocol led to close scores in both SAS (7.80 ± 1.03 vs. 8.07 ± 0.89, p = 0.21) and VAS (1.74 ± 0.85 vs. 1.78 ± 1.06, p = 0.84). CONCLUSIONS: Implementation of an ERAS protocol for patients undergoing MIE resulted in earlier ambulation and lower pulmonary complications, without a change in anastomotic leakage or length of hospital stay. Further studies on minimizing leakage should be addressed in ERAS for MIE
A SPA-weighted Arrhythmias-risks ValuatING (SAVING) Algorithm and Tested in WE-CARE 2.0
No full textVentricular tachyarrhythmia, in particular Ventricular Fibrillation (VF), is the primary arrhythmic event to cause Sudden Cardiac Death (SCD). Thus, the quick and accurate detection of a VF event is crucial for capturing the life-threat cardiac arrhythmias in real time. However, almost all existing VF detection algorithms are challenged by low accuracy or/and high complexity. To address this challenge, a Successive Projections Algorithm (SPA)-weighted Arrhythmias-risk ValuatING (SAVING) algorithm is proposed, in which SPA method is first applied to valuate arrhythmias-risk clinical features with using fisher criterion. Clinical trials show that it can obtain accuracy (Ac) of 96.81%, sensitivity (Se) of 95.41%, and specificity (Sp) of 97.15% in our WE-CARE 2.0 system. Compared to conventional algorithms, clinical tests demonstrate that the SAVING algorithm achieves comparative gains, which is a useful tool that can be embedded into WE-CARE systems and Automatic External Defibrillators.Beijing Nature Science Foundation [7152087]CPCI-S(ISTP
Hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside
No full textHydrogen (H2) is colorless, odorless, and the lightest of gas molecules. Studies in the past ten years have indicated that H2 is extremely important in regulating the homeostasis of the cardiovascular system and metabolic activity. Delivery of H2 by various strategies improves cardiometabolic diseases, including atherosclerosis, vascular injury, ischemic or hypertrophic ventricular remodeling, intermittent hypoxia- or heart transplantation-induced heart injury, obesity and diabetes in animal models or in clinical trials. The purpose of this review is to summarize the physical and chemical properties of H2, and then, the functions of H2 with an emphasis on the therapeutic potential and molecular mechanisms involved in the diseases above. We hope this review will provide the future outlook of H2-based therapies for cardiometabolic disease
Hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside
No full textHydrogen (H2) is colorless, odorless, and the lightest of gas molecules. Studies in the past ten years have indicated that H2 is extremely important in regulating the homeostasis of the cardiovascular system and metabolic activity. Delivery of H2 by various strategies improves cardiometabolic diseases, including atherosclerosis, vascular injury, ischemic or hypertrophic ventricular remodeling, intermittent hypoxia- or heart transplantation-induced heart injury, obesity and diabetes in animal models or in clinical trials. The purpose of this review is to summarize the physical and chemical properties of H2, and then, the functions of H2 with an emphasis on the therapeutic potential and molecular mechanisms involved in the diseases above. We hope this review will provide the future outlook of H2-based therapies for cardiometabolic disease.</jats:p
Neoadjuvant chemoradiotherapy followed by minimally invasive esophagectomy: is it a superior approach for locally advanced resectable esophageal squamous cell carcinoma?
No full textAn OCRNet-Based Method for Assessing Apple Watercore in Cold and Cool Regions of Yunnan Province
No full textThe content of the watercore in apples plays a decisive role in their taste and selling price, but there is a lack of methods to accurately assess it. Therefore, this paper proposes an OCRNet-based method for apple watercore content evaluation. A total of 720 watercores of apples from Mengzi, Lijiang, and Zhaotong City in Yunnan Province were used as experimental samples. An appropriate watercore extraction model was selected based on different evaluation indicators. The watercore feature images extracted using the optimal model were stacked, and the watercore content of apples in different regions was evaluated by calculating the fitted area of the stacked watercore region. The results show that the OCRNet model is optimal in all evaluation metrics when facing different datasets. The error of OCRNet is also minimized when extracting overexposed as well as underexposed images with 0.15% and 0.38%, respectively, and it can be used to extract the characteristics of the apple watercore. The evaluation result of the watercore content of apples in different regions is that Lijiang apples have the highest watercore content, followed by Mengzi apples, and Zhaotong apples have the least watercore content
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