188 research outputs found
Patient Preferences for Post‐Radical Cystectomy Treatment in Muscle‐Invasive Bladder Cancer: A Discrete Choice Experiment in Japan
No full textCitation: Shugo Yajima, Shinro Hata, Naoya Masumori, Yoh Matsuoka, Atsuro Sawada, Jun Miki, Mitsuhiro Tambo, Yasuyuki Kobayashi, Ayumu Matsuda, Keita Nakane, Takashi Kobayashi, Hajime Tanaka, Noriya Yamaguchi, Go Kaneko, Russell Miller, Takehiro Seto, Hiroaki Ito, Eiji Kikuchi, Patient Preferences for Post‐Radical Cystectomy Treatment in Muscle‐Invasive Bladder Cancer: A Discrete Choice Experiment in Japan, International Journal of Urology, 2025-03-10, https://doi.org/10.1111/iju.7003
A Case of Atazanavir Urolithiasis Diagnosed by Stone Analysis
No full textA 70-year-oldman was referred to our hospital for right back pain. His past history included human immunodeficiency virus infection, which had been treated with atazanavir for 7 years. Abdominal and pelvic computed tomographic scan showed right hydronephrosis due to a strongly suspected right ureteral radiolucent stone. He underwent indwelling of a right ureteral stent because of obstructive pyelonephritis due to the ureteral stone. After improvement of the pyelonephritis, he underwent transurethral ureterolithotripsy for the right ureteral stone. Stone analysis showed the atazanavir stone. He has been followed up for 8 months without evidence of recurrence. Herein, we report this rare case of an atazanavir stone in Japan, which was confirmedby calculus analysis, and present a review of the literature
A case of retrovesical leiomyoma
No full text61歳男性.患者は下腹部不快感, 排尿困難で受診し, 直腸診で前立腺部に軽度圧痛を認め, 慢性前立腺炎の診断でセルニチン・ポーレンエキスを投与し症状は軽快したが, CTで膀胱背側の左精嚢頭側に3×2cmの充実性腫瘍を認めたため手術目的で今回入院となった.直腸診では前立腺部圧痛は消失しており, 前立腺はクルミ大で弾性硬であった.骨盤CTで膀胱後腔の左精嚢頭側にiso-densityな腫瘍を認め, MRIでは腫瘍はT1, T2強調像ともに低信号, 辺縁は整で, 造影では緩徐に濃染され内部は不均一であった.膀胱, 直腸, 精嚢との連続性はなく, 後腹膜原発腫瘍と診断し腫瘍摘出術を行った.腫瘍は左精嚢の一部と癒着があり, 精嚢の一部と共に摘出した.病理所見では腫瘍は分化の良い筋組織で満たされ, 細胞異型は認めず, 後腹膜原発平滑筋腫と診断した.術後約6ヵ月経過現在で再発は認めていないWe herein report a rare case of leiomyoma in the retroperitoneal space posterior to the urinary bladder. A 61-year-old man came to our department complaining of lower abdominal discomfort. Abdominal and pelvic computed tomographic scan revealed a retrovesical solid tumor on the cranial side to the left seminal vesicle. Diagnostic imaging suggested that the retrovesical tumor was a benign tumor such as leiomyoma or fibroma, and he underwent simple resection of this retrovesical tumor via reroperitoneal approach. Histopathological diagnosis was well compatible with image diagnosis of leiomyoma. He has been followed up for 6 months without recurrence
Distinguishing testicular torsion from torsion of the appendix testis by clinical features and signs in patients with acute scrotum
No full textNaoyuki Fujita,1 Mitsuhiro Tambo,1 Takatsugu Okegawa,1 Eiji Higashihara,2 Kikuo Nutahara1 1Department of Urology, 2Department of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Research, Kyorin University School of Medicine, Mitaka, Tokyo Purpose: Many physicians encounter confusion and difficulty in distinguishing testicular torsion (TT) from torsion of the appendix testis (TAT) in patients with acute scrotum because of the overlapping signs and symptoms. The objective of our study was to evaluate the clinical features and signs that can help distinguish TT from TAT. Patients and methods: We performed a retrospective study of patients with surgically confirmed TT and TAT at our institute from January 1990 to December 2013. Clinical findings, physical examination findings, climatic conditions, laboratory data, and color Doppler ultrasound (CDUS) findings were compared between the TT and TAT groups. Results: Seventy patients were included in this study (49 with TT and 21 with TAT). Patients with TT were significantly older than those with TAT (p < 0.001). The ambient temperature at onset was significantly lower in patients with TT than in patients with TAT (p = 0.038). Testicular swelling, high-riding testes, onset during sleep, high leukocyte counts, and high creatine phosphokinase levels were significantly more common in patients with TT than with TAT (p = 0.021, 0.032, 0.006, 0.003, and 0.043, respectively). Multivariate analysis showed that age and onset during sleep were significant independent factors for detection of TT. Eight patients (16.3%) underwent preoperative CDUS evaluation, and an absent or decreased blood signal in the involved testes was significantly correlated with the presence of TT (p = 0.018). Conclusion: In clinical features, age and onset during sleep might be helpful to distinguish TT from TAT. When supported by findings, urgent surgical exploration is warranted in patients with suspected TT based on symptoms and CDUS features. Keywords: acute scrotum, testicular torsion, torsion of appendix testis, color Doppler ultrasoun
How ICTs Raise Manufacturing Performance: Firm-level Evidence in Southeast Asia.
No full textThis paper examines the effects of information and communication technologies (ICTs) on business performance, using firm-level data obtained through a questionnaire survey in four ASEAN countries (Indonesia, The Philippines, Thailand and Vietnam). Sources of information and new technologies exchanged via ICTs by firms are also explored to investigate the mechanism behind ICT adoption. Empirical results verify that the introduction of ICT to reorganize business processes is significantly correlated with business performance, in particular the development of export markets and improvement of production management. ICTs facilitate access to information and technologies accumulated in in-house departments and joint-venture (JV) affiliates of the respondent firms. There are considerable differences between multinational companies (MNCs)/JVs and local firms. MNCs/JVs make use of information and technologies obtainable via ICTs from their own R&D departments, JVs established with local partners and foreign-owned suppliers/customers to improve factory management, mostly for product quality improvement and production cost reduction. In contrast, local firms interconnect their own R&D departments via ICTs to enhance their business performance in broader areas than MNCs/JVs, including the development of export markets.
A case of vesical paraganglioma with intrapelvic multiplicity
No full text35歳女.高血圧を主訴とした.23歳時に高血圧の原因精査を行ない, 内分泌検査および画像所見から膀胱および骨盤腔内のparaganglioma疑いを指摘されたが放置していた.今回, 12年前より存在する膀胱paragangliomaの再精査・加療のため当科紹介入院した.経尿道的膀胱腫瘍生検を施行し, 病理組織学的にparagangliomaと診断し, 多発性腫瘍であり両側骨盤腔内リンパ節転移の可能性があったため, 下腹部正中切開, 後腹膜アプローチで膀胱部分切除術および骨盤腔内腫瘍摘除術を施行した.病理所見では, 膀胱筋層内に多発性のある大型細胞が胞巣状ないし充実性の増生を認めた.フローサイトメトリーによるDNA量解析では右骨盤腔内腫瘍のみにaneuploidパターンを認めたが, 他の膀胱部および左骨盤腔内腫瘍はdipoidパターンであった.術前に高値であった血中ドーパミン, 血中ノルアドレナリン, 尿中ノルアドレナリンは術後全て正常となり, 現在腫瘍の再発はないA 35-year-old woman, who had a past history of hypertension due to paraganglioma of the urinary bladder and in the pelvis, was referred to us 12 years after the initial diagnosis of paraganglioma. Before coming to us and during the follow-up after enucleation of myoma uteri, she was again diagnosed as having a bladder tumor by a gynecologist. Cystoscopy revealed a non-papillary broad-based tumor, measuring 2 cm in diameter, on the trigone of the urinary bladder. Magnetic resonance imaging also showed two solid tumors, each measuring 2 cm in diameter, on the bilateral peri-vesical sides in the pelvis. Endocrinologic examination disclosed increased levels of serum and urinary catecholamines. Histopathologic examination revealed that the bladder tumor specimen obtained by transurethral resection was paraganglioma. She underwent partial cystectomy and resection of these intrapelvic tumors via a retroperitoneal approach. These tumors were histopathologically diagnosed as multiple paragangliomas. She has been followed up for 10 months after operation without any evidence of recurrence. Herein, we report this rare case of vesical paraganglioma and present a brief review of the relevant literature
Separation and collection of coarse aggregate from waste concrete by electric pulsed power
No full textA case of inflammatory myofibroblastic tumor of the retroperitoneum
No full text46歳女.尿潜血を主訴とした.尿潜血のスクリーニングのため施行された腹部超音波断層検査で右腎外側に長径5cmと4cmの充実性腫瘍を認めた.腹部CTでは右腎外側に腎実質を圧排するように2つのiso-densityな腫瘍が存在し, 造影後期相では腫瘍辺縁部が比較的濃染された.腹部MRIで腫瘍はT1強調像で低信号, T2強調像で高信号を基調としており, 腫瘍辺縁部の信号強度がやや低く, 造影すると辺縁部がよく濃染された.画像所見上, 悪性線維性組織球腫あるいは脂肪成分に乏しい脂肪肉腫が疑われ, 後腹膜悪性腫瘍の術前診断のもとに, 腰部斜切開, 後腹膜アプローチにて腫瘍摘出および右腎摘除術を行った.腎との癒着や脂肪肉腫の術中迅速病理診断に基づいて腎の合併切除を行った.免疫組織化学染色から後腹膜原発のinflammatory myofibroblastic tumorと診断された.経過観察中で再発は認めていないHere we report a rare case of inflammatory myofibroblastic tumor of the retroperitoneal space. A 46-year-old woman had had microscopic hematuria for 5 years. Ultrasonographic examination for screening revealed two solid tumors adjacent to the right kidney. These tumors were suspected to be malignant fibrous histiocytoma or liposarcoma by computed tomography and magnetic resonance imaging. She underwent resection of these retroperitoneal tumors and additional right nephrectomy because these tumors were adhered to the kidney and liposarcoma was highly suspected on frozen sections. Histopathologic examination finally revealed that the tumors were inflammatory myofibroblastic tumor arising within Gerota's fasia. She has been followed up for 9 months without any evidence of local recurrence
Fabrication of FITC-doped silica nanoparticles and study of their cellular uptake in the presence of lectins
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