3 research outputs found
The level of police visibility in crime prevention in Zone II
No full textUM DIGOS Undergraduate Thesis (Department Of Criminal Justice Education)This study aimed to determined the level of police visibility in crime prevention in Barangay Zone II and to know the relationship of the level of police visibility towards the level of crime prevention. The study employed a descriptive-correlation research design. It was used in this study to find the significant relationship between the level of police visibility and crime prevention. The participants were the residents of Brgy. Zone Il and the police officers of Digos City. Results show that the overall level of crime prevention got the mean of 3.13 which also means much effective, this indicates that the scale of peace and order maintenance is high which shows a strong relationship of the police and the community. It is recommended that police patrol unit should regularly conduct motorcycle, mobile and foot patrol in Brgy. Zone II to serve as deterrence to perpetrator. The Barangay Zone II must organize Barangay Patrol Action Team and construct outpost situated strategically in the barangay. Local government unit should allocate budget for patrol activities. Barangay officials need to promote a crime prevention program in Brgy. Zone II in cooperation with law enforcement agency through crime prevention orientation to their constituents.UT 1269/P28/201839 PAGE
Purifications of small molecules that regulate neuronal cell-lineage specification
No full textThere are certain important factors that are essential for specification, development and maintenance vertebrate nervous system. During development these factors regulate axonal growth, dendrite pruning, cell fate decision and different other neuronal functions. In adult nervous system, they modulate synaptic activity and regulate neuronal connectivity. Cultivation of mammalian cells for production of recombinant protein has wide scientific and clinical applications because it offers many advantages especially the posttranslational modification. Human embryonic kidney (HEK) 293 cell lines expressing gene of interests will be constructed using calcium phosphate transfection of expression vectors. I have constructed stable cell lines for expressing large quantity of stable neurotrophic and neurological fate determinant factors including: Brain derived neurotrophic factor (BDNF),Glial derived neurotrophic factor (GDNF), Neurotrophin 3(NT3), Noggin and Sonic the hedgehog (SHH).This recombinant proteins were successfully purified by affinity chromatography and are tested on the conversion of induced pluripotent stem (iPS) cells into specific type of neurons, we found that some of the purified proteins are capable of support neuronal differentiation. These neurons have complex morphology, mature synaptic marker such as synapsin, and exhibit mature membrane properties and synaptic activity. We conclude that mammalian cell produced recombinant factors can be used to regulate human neuronal maturation and cell type specification.M.S.Includes bibliographical referencesby Aula Hamo
Lead screening in children presenting to three hospitals in Lebanon
No full textBackground Lead damages most body organs and its effects are most profound in children. In a study in Beirut in 2003, before banning the leaded gasoline, 79% of the participants showed blood lead levels (BLLs) higher than 5 µg/dL. The prevalence of lead exposure in Lebanon after the ban on leaded gasoline has not been studied. This study assessed the BLL in Lebanese children aged 1–6 years. Methods This cross-sectional study was conducted in three hospitals in Beirut. The children’s BLLs were tested, and their caregiver completed a questionnaire to identify subgroups at risk of exposure. Participants were provided with a WHO brochure highlighting the risks of lead. Results Ninety children with a mean age of 3.5±1.5 years were enrolled in the study and had a mean BLL of 1.1±0.7 µg/dL, with all values being below 5.0 µg/ dL, showing a marked decrease in BLL compared with the mean BLL before the ban on leaded gasoline in 2002. Having a father or a mother with a college degree (p=0.01 and p=0.035, respectively) and having a monthly household income greater than $1000 (p=0.021) were associated with significantly lower BLL. Having more rooms at home and residing close to construction sites were associated with a significantly lower BLL (p=0.001 and p=0.026, respectively). Residing in a house aged >40 years and receiving traditional remedies were associated with a significantly higher BLL (p=0.009 and p<0.0001, respectively). Conclusion BLLs have declined among Lebanese children and this could be attributed to multiple factors including the ban of leaded gasoline. It would be beneficial to conduct a larger study with a nationally representative sample to better characterise the BLL. © Author(s) (or their employer(s)) 2022
