4,136 research outputs found
In subclinical AF, the benefit of apixaban vs. aspirin on stroke or systemic embolism trended higher with CHA2DS2-VASc >4
Lopes RD, Granger CB, Wojdyla DM, et al. Apixaban vs aspirin according to CHA2DS2-VASc score in subclinical atrial fibrillation: insights from ARTESiA. J Am Coll Cardiol. 2024;84:354-364. 39019530
Hypoalbuminemia and Risk of Portal Vein Thrombosis in Cirrhosis
Background and aims: Hypoalbuminemia, as defined by serum albumin (SA) levels ≤35 g/L, is associated to venous and arterial thrombosis in general population and in patients at risk of cardiovascular disease. It is unknown if SA ≤35 g/L is also associated to portal vein thrombosis (PVT) in cirrhosis. Methods: Cirrhotic patients enrolled in the Portal vein thrombosis Relevance On Liver cirrhosis: Italian Venous thrombotic Events Registry (PRO-LIVER) study (n = 753), were followed-up for 2 years to assess the risk of PVT, that was diagnosed by Doppler ultrasonography. Child-Pugh classes, Model for End-Stage Liver Disease score, presence of hepatocellular carcinoma and laboratory variables including SA, D-dimer, and high-sensitivity C-reactive protein (hs-CRP) were measured at baseline. Results: SA ≤35 g/L was detected in 52% of patients. A logistic multivariate regression analysis showed that higher Child-Pugh class, hepatocellular carcinoma and thrombocytopenia were significantly associated to SA ≤35 g/L. In a subgroup of patients where data regarding hs-CRP and D-dimer were available, SA ≤35 g/L was inversely associated with hs-CRP and D-dimer. During the follow-up, a total of 61 patients experienced PVT. A Kaplan Meier survival analysis showed SA ≤35 g/L was associated to increased risk of PVT compared to SA >35 g/L (P = .005). A multivariate Cox proportional hazards regression analysis showed that male sex, lower platelet count, and SA ≤35 g/L remained associated to PVT after adjusting for confounding factors. Conclusion: Cirrhotic patients with SA ≤35 g/L are at higher risk of experiencing PVT compared to those with SA >35 g/L and could be considered as potential candidates to anticoagulant prophylaxis for PVT prevention
Le «buone letture». 2. Giovanni Casati
Il saggio è costituito da due parti, la prima delle quali, dedicata alla fondazione della Federazione italiana delle biblioteche circolanti cattoliche, è stata pubblicata nel precedente numero dei «Nuovi Annali», XXVII (2013), pp. 137-163. In questa seconda parte viene delineata la figura intellettuale di Giovanni Casati, che diresse la «Rivista di letture» dal 1912 al 1944, trasformando il periodico della Federazione in una rivista impegnata nella divulgazione della cultura cattolica. A questo impegno militante Casati fece corrispondere un intenso programma editoriale, che trovò espressione nella pubblicazione di saggi letterari, di manuali e opere repertoriali.The study consists of two parts; the first is dedicated to the history of the Federazione italiana delle biblioteche circolanti cattoliche since its foundation (1904) up to 1912 and was published in the previous volume of the «Nuovi Annali », XXVII (2013), pp. 137-163. In this second part, the author outlines the intellectual figure of Giovanni Casati, who directed the «Rivista di letture» from 1912 to 1944, transforming the magazine of the Federation in a journal engaged in the spreading of Catholic culture. To this militant engagement Casati matched an intense publishing program, which found its expression in the publication of literary essays, manuals and reference works
Comico e tragico del diritto nella novellistica italiana: il novelliere di Giovanni Sercambi
Nelle novelle di età tardomedievale ed umanistica, a causa del loro carattere fortemente realistico, il diritto ha un posto importante, poiché rappresenta un elemento centrale e ineliminabile della vita della comunità. Il novelliere di Giovanni Sercambi da Lucca non fa eccezione, anche se l’autore non ha una cultura giuridica né s’interessa in modo specifico al diritto. Il presente saggio vuole analizzare sotto tale profilo queste novelle per verificare quale concezione del diritto emerge da esse e come la narrazione ne risulti arricchita.In the late medieval and humanistic novellas, owing to their very realistic character, the right is an important central and inevitable element in community life. Giovanni Sercambi’s novelliere is no exception even if the author lacks a legal culture, nor is specifically interested in right. This essay intends to analyze these novellas under this profile to verify what kind of right they consider and how the stories are enriched
Bird presence vegetation complexity data in Melbourne, Australia. Data created in 2018 by Giovanni Carrabs.
Bird presence and vegetation complexity data from Melbourne, Australia. Data created for a university thesis project and publication in 2018. Author: Giovanni Carrabs.</p
Asymptomatic peripheral artery disease and antiplatelet management
Peripheral arterial disease (PAD) is a hallmark of generalized atherosclerosis. Depending on the specific diagnostic criteria that are being used, the prevalence of PAD may be as high as 30 % in the population of people 70 or more years old. Unfortunately, although PAD is prevalent and has many important consequences for patients, it is often under-detected and under-treated by primary care physicians. The aim of this review is to provide an overview of the available literature on epidemiology and antiplatelets management of PAD patients. In particular, we focus on the "hidden" side of PAD burden, the asymptomatic patients, who are at high risk of negative cardiovascular outcomes. Identification of such PAD patients is therefore an important clinical goal to reduce mortality and morbidity and reduce the social cost of atherosclerotic disease. Early screening of PAD and an evidence-based antithrombotic approach are also discussed as potential strategies to counteract the negative impact of such condition in general population, as well as, in patients with other cardiovascular disease
High versus low chloride load in adult hyperglycemic emergencies with acute kidney injury: a great fluid debate
Chapter Atto biografo di Giovanni Gualberto
The paper examines the Vita s. Iohannis Gualberti by Atto, reconstructing its genesis and fortune. Probably the author wrote this hagiography when he was abbot and before becoming bishop of Pistoia. He re-elaborated the Life of the saint by Andrea of Strumi, adapting it to a changed historical and ecclesiastical context. The text was successful among the Vallombrosan Order and it was used by later hagiographers to create epitomes and rewritings of the Life of Giovanni Gualberto
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