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Immunohistochemical study of secretory IgA in the human male reproductive tract.
No full textMale human genital tract was treated for the immunohistochemical demonstration of secretory IgA in order to verify its own possible antimicrobial properties. An intensely positive immunoreaction for sIgA in the epithelial cells of prostate and urethral glands was observed; in the same organs the presence of immunoreactive cell clusters in the subepithelial layers was noted. Immunostaining in the epithelia of deferent duct, seminal vesicle, deferential ampulla, ejaculatory duct and bulbourethral glands was absent. The findings suggest that a local immune response sIgA-mediated is present in the lower male genital tract
Human urethral epithelium: immunohistochemical demonstration of secretory IgA.
No full textMale human urethral epithelium was treated for the immunohistochemical demonstration of secretory IgA in order to verify its own possible antimicrobial properties. An intense immunoreactivity for sIgA in the entire cytoplasm and at the luminal surface of the apical epithelial cells was observed. The results suggest that sIgA play a prominent role in the local defense mechanisms of the urethra. Such mucosal defense mechanisms may be of significance in the defense of the urinary and genital tract against ascending infections
Immunohistochemical localization of secretory immunoglobulins in the main excretory duct of the human submandibular gland.
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Immunohistochemical study of some specific defense mechanisms in the external auditory canal.
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