1,720,996 research outputs found
Indagini semeiologiche nelle uveiti infantili
No full textLa semeiologia nelle uveiti si è progressivamente arricchita di una serie di esami che consentono oggi una valutazione più precisa delle caratteristiche del processo flogistico, purtroppo non è invece di aiuto nell' inquadramento eziologico.
Gli esami devono essere accuratamente programmati a seconda delle caratteristiche dell'uveite e dell'età e della collaborazione del pazient
Decreased Geometric Complexity of Corneal Nerve Fibers Distribution in Sjogren’s syndrome Patients
No full textObjective: Dry eye affects many individuals worldwide and a significant portion of patient with dry eye present the Sjogren’s syndrome (SS), a progressive, autoimmune condition. In order to choose and follow the best therapy it’s necessary to have noninvasive quantitative methods able to characterize the status of the corneal nerve fibers of the patients.
Methods: Local fractal dimension by box-counting (evaluation of geometric complexity) of the nerve corneal fibers distribution observed by confocal microscopy was performed in patients with primary SS (n=36: 6 males, 30 females, 21- 81 years), diagnosed by biopsy of salivary gland and blood tests and in sex- age-matched healthy subjects (n=12). In selected patients salivary glands atrophy degree was also evaluated.
Results: Fractal analysis reveals that the nerve corneal distribution is fractal. In healthy subjects the fractal dimension of the corneal nerve distribution is close to the value of the Diffusion Limited Aggregation Process, a typical value of geometric complexity in normal individuals. Geometric complexity statistically distinguishes between Sjogren’s syndrome patients and healthy subjects: patients present a lower value of geometric complexity of the corneal nerve fibers distribution than healthy individuals (p<0.001). The percentage of grouped cases classified by geometric complexity (D cut-off =1.40) according to the subjects (SS patients vs healthy) showed a 100% ratio between the number of correctly classified cases and all cases, p<0.001. The nonlinear index correlates with salivary glands atrophy degree (p<0.01).
Conclusions: Fractal analysis of the cornea observed by a laser confocal microscopy appears able to quantitatively and nonivasively characterize the SS patient in relation to the recognition of an impairment of the ocular surface. The analysis is inexpensive and not time-consuming, of relevance in order to choose the best therapy
Response to the letter to the editor entitled "Forty-two-month outcome of intravitreal bevacizumab in myopic choroidal neovascularization"
No full text
Manual deep lamellar keratoplasty: alternative methods and air-guided technique.
No full textPurpose. To describe the techniques proposed for performing deep lamellar keratoplasty
(DLK) and to evaluate the efficacy of a new, modified technique.
Methods. Fourteen eyes in 11 patients with keratoconus of moderate degree were
included. All patients underwent a DLK with manual dissection from a limbal side port
after an air bubble injection in the anterior chamber. All patients had complete
ophthalmologic examination 6 months after the suture removal, evaluating best corrected
visual acuity, corneal thickness, endothelial cell count, and topographic astigmatism.
Results. One case (7.1%) was converted to penetrating keratoplasty because of microperforation.
In the 13 successful cases, 10 eyes (71.4%) achieved 20/30 or better 6 months
after suture removal. Mean postoperative pachymetry was 628.39 (SD 57.34). Specular
microscopy 6 months after suture removal revealed average endothelial cell count of 2261
(SD 287/mm2).
Conclusions. Comparing this modified DLK technique with other methods proposed by
several authors, air-guided DLK seems to be safe and effective and, after a short learning
curve, can be performed with a low risk of conversion to penetrating keratoplasty
Uveiti prevalentemente posteriori ed entità cliniche di incerta definizione
No full textLe uveiti, nonostante gli innumerevoli progressi della immunologia e della infettivologia, comportano a tutt'oggi per l'oculista un impegno diagnostico e terapeutico notevole.
Gli autori riportano le possibili cause di uveite posteriore infantili considerando tra queste anche quelle di più incerta etiologia ed identificazion
Laser therapy for neovascular glaucoma prophylaxis after retinal veins occlusions [PROFILASSI DEL GLAUCOMA EMORRAGICO CON LASER TERAPIA NELLE OCCLUSIONI VENOSE RETINICHE]
No full textIndicazioni e valutazione degli esami infettivologicici
No full textL'utilità della diagnostica di laboratorio nelle uveiti è ancora discussa tra gli specialisti.
Un approccio mirato stimola le conoscenze dello specialista e la sua capacità critica nella diagnosi differenziale considerando innanzitutto le caratteristiche cliniche di ciascuna entita
Closed-system and open-sky capsulorhexis for combined cataract extraction and corneal transplantation.
No full textWe describe a triple procedure combining corneal transplantation, cataract extraction, and intraocular lens implantation in which the continuous curvilinear capsulorhexis (CCC) is performed in a closed system when corneal transparency is sufficient or using an open-sky method when corneal transparency is poor. With the closed system, the CCC is performed first followed by trephination and hydroexpulsion of the nucleus. A Caporossi coaxial forceps is used to reduce the corneal incision to 1.2 mm, preventing the need for sutures. Tunnel formation, which could limit the size of trephination, is avoided. In addition, endothelial cell loss at the periphery of the recipient cornea is reduced. This technique was performed in 10 eyes without intraoperative complications. With the open-sky method, the CCC is created while counterpressure is applied to the center of the lens with a large spatula, reducing posterior pressure and thus the risk of capsule tear. This technique was performed in 9 eyes without intraoperative complication
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