1,721,066 research outputs found
Apparent volume measurements for capsule excipients with relation to the working conditions
No full textSome clarifications regarding ozone therapy vs retinal vascular reactivity
No full textNo abstract availabl
Esters of hyaluronic acid with rhein, process for their preparation and compositions comprising the same
No full text
Commercial pregelatinized starches: ability to settle and rheological evaluation
No full textThe ability to settle and the tribological properties of three samples of pregelatinized starch widely
available commercially were investigated with reference to their technological implications. In particular,
we evaluated the influence of storage conditions, storage time, moisture content, equipment, handling,
and mechanical treatment on the apparent volume, poured density and tapped density, as well as
on tests of flow parameters such as basic flowability energy. The results obtained highlight the fact
that the technologically relevant behaviour of pregelatinized starches in terms of apparent volume and
tribological properties may be influenced not only by relative humidity (RH%) conditions, but also by
common pharmaceutical operating practices. In particular, previous mechanical treatment can lead to
statistically different behaviour in tests of ability to settle according to pharmacopoeial specifications,
depending on both RH% conditioning and the amount of powder, although the materials under investigation
all conform to the respective monograph in the Pharmacopoeia. All these aspects are of special
interest with regard to the various pharmaceutical formulations which include pregelatinized starch,
both on an industrial scale and in small-scale production
- …
