28 research outputs found
sj-docx-1-smo-10.1177_20503121231224549 – Supplemental material for Assessment of knowledge, attitudes, and practices of occupational risks and diseases among healthcare providers of the Regional Hospital Center of Dosso, Niger
No full textSupplemental material, sj-docx-1-smo-10.1177_20503121231224549 for Assessment of knowledge, attitudes, and practices of occupational risks and diseases among healthcare providers of the Regional Hospital Center of Dosso, Niger by Halimatou Nassirou-Sabo and Moussa Toudou-Daouda in SAGE Open Medicine</p
Influence des antiépileptiques sur les hormones thyroïdiennes. Influence of antiepileptic drug on thyroid hormones
No full textInfluence des antiépileptiques sur les hormones thyroïdiennes Influence of antiepileptic drug on thyroid hormone
Epilepsy in Niger: An overview of the current situation
No full textAbstract A major public health concern in the world, particularly in sub‐Saharan African countries, epilepsy is poorly studied in Niger, and its prevalence in the general population is unknown. Only two hospital‐based studies have been published in Niger, reporting an estimated mean hospital prevalence of epilepsy of 24.2% (95% CI: 23.2–25.2), mainly affecting patients younger than 18 years (54.6%, 95% CI: 52.2–57.0), and males (59.8%, 95% CI: 57.4–62.2). To date in Niger, people living with epilepsy (PWE) are usually cared for by non‐physician healthcare workers (mainly nurse technicians in mental health), general medical doctors (non‐specialist physician), and non‐neurologist physicians. In routine practice, these health workers make the diagnosis of epilepsy essentially based on the clinic, i.e., the repetition of epileptic seizures over time (mainly generalized tonic–clonic seizures) because most of them practiced in health centers or district hospitals or regional hospital centers in which electroencephalogram and neuroradiological explorations are of limited access or unavailable as well as a referral neurologist. Only 10 neurologists are currently practicing in Niger for a total population estimated at 21466800 inhabitants by the World Health Organization in 2018. In 41.8% (95% CI: 39.4–43.2) of the cases, the etiology was unknown with neuroradiological explorations and laboratory tests not performed in most cases. Genetic etiologies are the most frequent etiologies (40.8; 95% CI: 38.4–43.2), followed by Structural etiologies (11.7; 95% CI: 10.1–13.3) particularly hypoxic–ischemic brain injury, and infectious etiologies (6.8%; 95% CI: 5.6–8.0), especially cerebral malaria. PWEs are the target of social stigma and discrimination due to erroneous cultural and religious beliefs about epilepsy of the people from Niger. The present review is an update on the different aspects of epilepsy in Niger
Céphalées épileptiques isolées : revue de la littérature. Isolated epileptic headache : review
No full textLes céphalées épileptiques isolées sont des céphalalgies migraineuses associées à des décharges épileptiques électroencéphalographiques per-critiques sans d’autres phénomènes épileptiques associés notamment somatosensitifs, somatomoteurs ou autonomiques. Sur le plan physiopathologique, les céphalées épileptiques isolées correspondent aux manifestations cliniques des décharges épileptiques focales subcliniques des neurones corticaux qui engendrent une dépression corticale propagée ou ‘’cortical spreading depression’’. Cette dernière active le système trigéminovasculaire qui déclenche les céphalalgies migraineuses sans qu’il ait d’autres signes ou symptômes épileptiques associés. Le diagnostic des céphalées épileptiques isolées se fait devant un tableau des céphalalgies migraineuses, qui durent quelques secondes à quelques minutes voire des heures ou jours, associées à des décharges épileptiques électroencéphalographiques per-critiques homolatérales ou controlatérales et qui se résolvent immédiatement après injection intraveineuse des antiépileptiques. Dans cet article de mise au point, nous exposons l’état des connaissances actuelles sur les céphalées épileptiques isolées afin d’attirer l’attention des praticiens à ne pas méconnaitre cette entité clinique et de permettre une meilleure prise en charge des patients qui en souffrent
Hurler–Scheie syndrome in Niger: a case series
No full textAbstract Background Hurler–Scheie syndrome is an intermediate form of mucopolysaccharidosis type I which is a rare lysosomal storage disorder caused by the deficiency or complete absence of enzyme alpha-L-iduronidase activity. We report the first documented cases of Hurler–Scheie syndrome observed in Niger in a Touareg family. Case presentation We studied the case of two 12-year-old twin Touareg boys and their 10-year-old Touareg sister whose parents are first-degree cousins, and there was no history of similar cases in their previous generations. The diagnosis of Hurler–Scheie syndrome was considered in these patients on the basis of clinical and radiological arguments, with the highlighting of a deficiency of enzyme alpha-L-iduronidase in serum and leukocytes. The twins had presented the first symptoms at the age of 24 months and the diagnosis of Hurler–Scheie syndrome was made at the age of 12 years. In their younger sister, the first symptoms were observed at the age of 3 years and the diagnosis was made at the age of 10 years. The three probands were born after a normal full-term pregnancy and a spontaneous vaginal delivery according to their parents. Their birth weight, height, and head circumference were within normal limits according to their parents. The three probands were brought in for consultation for stunted growth, joint stiffness with gait disorders, deformities of the thoracolumbar spine, recurrent otitis media, decreased hearing, increased abdominal volume, snoring during sleep, and facial dysmorphism. Conclusions Even in countries with limited access to diagnostic means, a good knowledge of the clinical manifestations of the disease can help to guide the diagnosis of mucopolysaccharidosis type I
Knowledge, Attitudes, and Practices with Respect to Epilepsy among Nurses in the City of Niamey, Niger
No full textKnowledge, attitudes, and practices with respect to epilepsy among primary and secondary school teachers in the city of Niamey, Niger
No full textClinical and Etiological Characteristics of Epilepsy in the Elderly: A Hospital-Based Study from a Tertiary Care Referral Center of Niamey, Niger
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