102,964 research outputs found
Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC).
No full textMetro G, Finocchiaro G, Toschi L, Bartolini S, Magrini E, Cancellieri A, Trisolini R, Castaldini L, Tallini G, Crino' L, Cappuzzo F. Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC). Reviews on recent clinical trials. 2006;1:1-13
Breakdown of Traditional Many-Body Theories for Correlated Electrons
No full textStarting from the (Hubbard) model of an atom, we demonstrate that the uniqueness of the mapping from the interacting to the noninteracting Green function, G -> G(0), is strongly violated, by providing numerous explicit examples of different G(0) leading to the same physical G. We argue that there are indeed infinitely many such G(0), with numerous crossings with the physical solution. We show that this rich functional structure is directly related to the divergence of certain classes of (irreducible vertex) diagrams, with important consequences for traditional many-body physics based on diagrammatic expansions. Physically, we ascribe the onset of these highly nonperturbative manifestations to the progressive suppression of the charge susceptibility induced by the formation of local magnetic moments and/or resonating valence bond (RVB) states in strongly correlated electron systems
Le sostanze recuperabili dai reflui oleari: aggiornamento della ricerca applicata
No full textIl libretto descrive le attività condotte nel triennio 2009-2011 di dimostrazione d'uso e di possibilità offerte da un impianto di filtrazione delle acque di vegetazione portatile, assemblato in un container.
Si tratta di un progetto finanziato dalla Comunità Europea, attraverso l'associazione di produttori oleari della Regione Emilia-Romagna ARPO.
Il capitolo, nello specifico, affronta gli aspetti analitici e di valutazione della qualità degli estratti (dai concentrati) di fenoli ottenuti e delle acque (dai permeati)
A cross-country study on investment readiness. How can entrepreneurs increase attitude towards equity finance?
No full textThe creation and growth of high quality Small and Medium-sized Enterprises (SMEs) contributes to improvements in productivity from which the whole economy can benefit. However, the presence of market imperfections create difficulties for SMEs seeking external sources of equity finance to support the early stages of their growth. From the supply side, this equity gap is created by high transaction costs, ongoing running costs, high risk and uncertainty, and lack of exit options. From the demand side, the entrepreneurs‘ limited understanding of equity instruments, poor intrinsic quality (and presentation) of business plans, and a reluctance to share/cede control reduce the attractiveness of SMEs to formal equity financiers. We term such SMEs as ̳not investment ready‘. In order to tackle this crucial component of the equity gap, a range of targeted measures have been designed to increase the level of investment readiness and thus help those SMEs that wish to attract equity finance. This report will review publicly funded (either in whole or in part) investment readiness schemes in different countries (the European Union, USA, Canada, Australia and New Zealand), with the aim of understanding: (a) how effective these schemes are, (b) the extent to which they have been evaluated, (c) the results of the evaluations (d) and what lessons can be learned in designing future UK policies
Economia de la integracion regional.
No full text¿Cuáles son los motivos que han inducido a los Países Europeos a fundar la Comunidad Europea y, posteriormente, reforzar el acuerdo a través de la Unión Europea? ¿Qué motivaciones son las que llevan a otros Países a solicitar la adhesión a la UE, aceptando reglas y políticas ya establecidas por otros y aceptando, además, afrontar costos de ajustes particularmente elevados? ¿Qué es lo que empuja, fuera de la UE, a realizar intentos, como el Mercosur, para lograr acuerdos de integración regional dirigidos a la creación de un mercado interno liberalizado e integrado? Aún más, ¿cuál es la motivación de la existencia de períodos alternados de entusiasmo o de pesimismo en el proceso de construcción europea? ¿De qué modo la teoría económica puede dar una respuesta a estas preguntas?
Este libro pretende brindar a los estudiantes universitarios y a los operadores económicos interesados, la posibilidad de profundizar los conocimientos teóricos –y las relativas aplicaciones concretas– sobre la integración económica regional. Los estudiantes adquirirán habilidades específicas sobre el uso de los principales modelos elaborados por la ciencia económica para explicar las motivaciones y las consecuencias de los acuerdos regionales: tales habilidades permitirán a ellos afrontar el análisis de situaciones reales, en particular, de los éxitos y los malogros del proceso de integración Europea, en las otras áreas de integración regional, y de las perspectivas futuras de profundización
Influence of age at weaning and nutritive value of weaning diet on growth performance and caecal traits in rabbits
No full text[EN] To investigate the relationship between dietary nutrient concentration and weaning age on growth performance and caecal characteristics of rabbits, a trial was carried out on 64 litters (eight rabbits/litter) comparing two weaning ages (25 vs. 34 d) and two diets (HC: high concentrated and LC: low concentrated diet) offered to the kits from 18 to 34 d of age. At 34 d of age 54 animals per group were caged individually and all were fed the LC diet until 45 d of age. All animals were then fed a standard fattening diet (37% neutral detergent fiber, 3.4% ether extract and 18.0% crude protein on dry matter basis) until slaughter at 80 d. The digestibility trial was performed from 56 to 60 d of age on another group of 16 rabbits (8 per diet). During the experimental period (18-80 d of age), feed intake and animal weights were recorded. Caecal volatile fatty acids were measured at 45 and 80 d of age, while microbiological analysis was performed at 25 and 34 d on healthy suckling rabbits. Digestibility of dry matter, protein, neutral detergent fiber, fat and energy was higher in rabbits fed the HC diet (by 7.7, 7.4, 13.1, 26.7, 10.6%, respectively; P<0.001) than in those fed the LC diet. Growth rate and feed conversion ratio (FCR) from 18 to 34 d improved by 7.7 and 9.5% in rabbits fed HC in comparison to the LC diet, respectively (P¿0.061). Diet offered around weaning did not influence growth rate or FCR from 34 to 80 d of age. Rabbits weaned earlier increased feed intake (by 67.8%) from 25 to 34 d, but reduced growth rate (by 26.8%) compared to animals weaned at 34 d (P<0.001). Early weaning reduced live weight during the entire fattening period (P¿0.018), as well as the FCR (by 4%; P<0.001). Caecal pH was lower at 45 d of age in rabbits weaned at 25 d than in those weaned at 34 d (5.53 vs. 5.83; P=0.019). Treatments did not affect total caecal VFA concentration, but HC diet decreased caecal acetic concentration and increased butyric acid level compared to the LC diet at 45 d (P¿0.001). HC diet tended to reduce caecal counts of Enterobacteriacae (P=0.093), while it did not affect facultative anaerobic bacteria, E. Coli and Costridium spp. The LC diet increased at 25 d the number of Clostridium perfringens in comparison with the HC group at the same age and in comparison with animals fed both two diets at 34 d (P<0.001). The values of E. Coli and Enterobacteriaceae increased (P¿0.008) from 25 to 34 d of age, whereas that of Clostridium spp. decreased. Weaning at 25 d increased mortality from 18 to 34 d compared with rabbits weaned at 34 d (7.02 vs. 2.46%, P=0.017). However, during the fattening period (34-80 d) rabbits weaned earlier showed lower mortality (7.41 vs. 17.6%; P=0.024).This work has been realized within the CUNISVEZZ research project financed by the Agricultural Department
of the Regione Lombardia as part of the 2004 research and development plan, d.g.r. 30/04/2004 n. VII/17326. The authors wish to thank Nicoletta Cesari for her technical assistance.Cesari, V.; Grilli, G.; Ferrazzi, V.; Toschi, I. (2009). Influence of age at weaning and nutritive value of weaning diet on growth performance and caecal traits in rabbits. World Rabbit Science. 17(4):195-205. https://doi.org/10.4995/wrs.2009.64419520517
Detection of low-quality extra virgin olive oils by fatty acid alkyl esters evaluation: a preliminary and fast mid-infrared spectroscopy discrimination by a chemometric approach
No full textA set of eighty-one extra virgin olive oils (EVOOs) was analysed according to the new quality parameters relative to the total amount of methyl and ethyl esters of fatty acids [Σ(FAMEs +FAEEs)] and the ratio between ethyl and methyl esters [ratio of FAEEs/FAMEs (RFF)]. Acquisition of the midinfrared spectra was also performed by Fourier Transform Infrared Spectroscopy (FT-IR). Chemical and spectroscopy data were chemometrically elaborated, and FT-IR coupled by Partial Least Square (PLS) methodology was developed. Results were statistically similar to official procedure in terms of analytical performance forΣ(FAMEs +FAEEs) and RFF in EVOOs: a good agreement between predicted and actual values on calibration data sets was found (0.98 and 0.83, respectively) and the limit of quantification was low enough (29.3 mg /kg) considering the actual limits for Σ(FAMEs+FAEEs). This new approach, time-saving and environmentally friendly, can be considered as a useful tool for screening procedures.Fil: Valli, Enrico. Universidad de Bologna; ItaliaFil: Bendini, Alessandra. Universidad de Bologna; ItaliaFil: Maggio, Ruben Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Instituto de Química Rosario; ArgentinaFil: Cerretani, Lorenzo. Universidad de Bologna; ItaliaFil: Gallina Toschi, Tulia. Universidad de Bologna; ItaliaFil: Casiraghi, Ernestina. Universita Degli Studi Di Milano; ItaliaFil: Lercker, Giovanni. Universidad de Bologna; Itali
Studio della doppia lattazione nel coniglio : effetto sulla produzione di latte, sull’ingestione e sulle performance della nidiata
No full textDouble lactation in rabbits: effect on milk production, feed intake and performance of litters. Does double lactation influence growth performance of litters? To answer this question, 42 multiparous rabbit does and their offspring were allocated to 3 groups, characterized by different frequency of lactation: free (group L), once a day (group S), double lactation (group D). The total milk production of group L (similar to that of group D) was higher (P<0,05) than that of group S (5,71 vs. 5,33 kg). The solid feed intake, from day 28 day onward, was higher (P<0,01) for D than L litters (41,2 vs. 33,6 g/d). At weaning, the weight of litters D and S was lower than that of group L (5150, 5042 and 5559 g, for D, S and L, respectively). Mortality rate did not differ between groups throughout the experimental period. These data, together with the scarce willingness of does to get into the nest box for the second lactation, suggest that the double lactation method could be useful only using hybrid characterized by high milk production. The better performance obtained with the free lactation confirm that the duration of controlled nursing could be carry out for a restricted period to prevent decrease of litter growth
Giorgia Lupi, l’arte dei dati e il nuovo umanesimo
No full textAlle forme di autoconfigurazione delle prime stagioni selfmediali si impongono ora pratiche di automisurabilità, che precipitano la dimensione “auto”, cioè relativa all’implicito autoriale della ritrattistica,
Il saggio analizza due l'opera di Giorgia Lupi con particolare riferimento a Dear Data (Lupi-Posavec) e Bruises (Lupi-Cooper
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