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A special case of bilateral ovarian metastases in a woman with papillary carcinoma of the thyroid
No full textPapillary thyroid carcinoma is a slow growing tumor with low metastatic
potential. The most frequent sites of distant metastases are lung and bone; less
frequent sites are brain, liver, kidney, and skin. Ovarian metastases from
papillary thyroid carcinoma are exceptional. We describe a case of bilateral
ovarian metastases from a papillary thyroid carcinoma associated with autoimmune
thyroiditis in a 38-year-old woman who underwent thyroidectomy and cervical
lymph-node dissection 7 years before, followed by 948 mCi of 131I. A primary
ovarian cancer could be excluded by the typical pathological aspects of a
papillary thyroid carcinoma in a context of an aggressive form of thyroid cancer.
On the other hand, the clinical history and the absence of normal thyroid
epithelium and teratomatous components could exclude a papillary thyroid
carcinoma arising in struma ovarii. This is a singular case of papillary thyroid
carcinoma metastasizing to the ovary, combined with an autoimmune thyroiditis
Recombinant human TSH as an adjuvant to radioiodine for the treatment of type 1 amiodarone-induced thyrotoxicosis: a cautionary note
No full textContinuation of amiodarone delays restoration of euthyroidism in patients with type 2 amiodarone-induced thyrotoxicosis treated with prednisone: a pilot study
No full textMinimally invasive video-assisted thyroidectomy versus conventional thyroidectomy in pediatric patients
No full textAbstract Background Minimally invasive video-assisted thyroidectomy (MIVAT) proved to be safe and effective in the treatment of both benign and malignant disease. The aim of the present study is to compare MIVAT approach with conventional approach for total thyroidectomy in a group of 99 pediatric patients operated in the Department of General Surgery of the University of Pisa between March 2007 and July 2012. Patients A total of 99 pediatric patients under the age of 18 years with thyroid disease referred to our Department to undergo total thyroidectomy. Patients were divided into two groups according to the surgical technique performed: 34/99 (34.3%) patients (MIVAT group [MG]) and 65/99 (65.7%) patients, (conventional group [CG]) who underwent total thyroidectomy, respectively, with MIVAT approach and conventional approach. Results In MG mean operative time for total thyroidectomy was 40±6.57 minutes (range 30-60 min); postoperative hospital stay was 1 day for 18 patients (53%), 2 days for 12 patients (35.25%), 3 days for 4 patients (11.8%); transient hypoparathyroidism (hypoPTH) was observed in 12 cases (35.3%) and permanent hypoPTH in 2 cases (5.9%); transient postoperative unilateral vocal cord palsy was observed in 2 patients (5.9%). In CG mean operative time for total thyroidectomy was 49.3±12.9 minutes (range 30-80 min); postoperative hospital stay was 1 day for 16 patients (24.6%), 2 days for 40 patients (61.5%), 3 days for 8 patients (12.3%), and 4 days for 1 patient (1.6%); transient hypoPTH was observed in 23 cases (35.4%) and permanent hypoPTH in 4 cases (6.1%), who needed therapy with calcitriol and calcium carbonate; transient postoperative unilateral vocal cord palsy was observed in 4 patients (6.1%). There were no cases of permanent vocal cord paralysis in both groups. The correlation between two groups of patients showed that mean operative time was significantly lower in MG (p=0.0007). Conclusion Pediatric patients of MG showed a significantly lower operative time and postoperative hospital stay with respect to pediatric patients of CG if compared with conventional technique. This result with the evidence of similar degree of completeness and rate of postoperative complications make MIVAT a valid option for the treatment of pediatric patients when performed by a well-trained staff in a third referral center
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