100,458 research outputs found
Oenological characterisation of indigenous strains of S. cerevisiae isolated in a biodynamic winery in the Cortona DOC area
No full textGenotypic and technological characterisation of the S. cerevisiae population isolated in a biodynamic winery in the Cortona DOC area was performed to gain better knowledge of the variables that influence winemaking. The oenological performance of 11 S. cerevisiae strains was evaluated with physiological tests; strain typing was performed through analysis of interdelta sequences and 26S rDNA sequencing. The analysis revealed a remarkable variability in terms of S. cerevisiae strains, despite the homogeneity of wine features, underlining the high levels of biodiversity characterising biodynamic agriculture. Some strains were found in wines of different vintages, suggesting the presence of an established microbiota in the winery. Oenological tests demonstrated that while some yeasts provided reliable oenological performance, other strains were not able to accomplish prompt and effective alcoholic fermentation, or were characterised by spoilage characteristics, such as excessive production of volatile phenols or acetic acid. Indigenous strains of S. cerevisiae could be a useful instrument for reliable winemaking without altering the native microbiota of each oenological environment. However, characterisation of their oenological suitability, and the application of practices able to drive the evolution of microbiota, must be employed to reduce the risk of wine spoilage
Ovarian Stimulation for Infertility in a Woman With Bipolar I Disorder
No full textNo abstract availabl
Corporate social responsibility to prevent human trafficking. Immigrant workers in Italian agriculture – A mapping
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Psychosis in Patients in COVID-19-Related Quarantine: A Case Series
No full textWhile the long-term mental health effects of previous pandemics and related quarantines have been reported in the literature, research is scarce with regard to the first stages of this type of emergency situation. Sudden social isolation, societal restrictions, and virus-related fears may serve as precipitating factors in vulnerable individuals for many types of psychiatric conditions. The literature reports that individuals who are mentally vulnerable to environmental stressors can be deeply affected by quarantines,2 but no data are yet available regarding the collateral effects of the coronavirus disease 2019 (COVID-19) infection on the onset of acute psychosis.
We describe 3 clinical cases of patients admitted to the psychiatric ward of the Padua University Hospital, Padua, Italy, following the enactment of quarantine measures in the Veneto region of northeastern Italy. All 3 admissions occurred in a period of less than a week (March 20-25, 2020), starting 10 days after initiation of strict societal restrictions in the country
Middle Eocene to early Oligocene calcareous nannofossil biostratigraphy at IODP Site U1333 (equatorial Pacific)
No full textWe present a biostratigraphic and biochronologic study of calcareous nannofossils of middle Eocene - early Oligocene age recovered during IODP Expedition 320, at Hole U1333C in the equatorial Pacific Ocean. The study succession encompasses nannofossil Zones NP16–NP21 (equivalent to CP13–CP16) and Chrons C20r–C12r (middle Eocene-early Oligocene). The distribution patterns of calcareous nannofossil taxa are studied by means of relative abundance and semiquantitative counts with the final aim to test the reliability of biohorizons used in the Paleogene standard biozonations (Martini 1971; Okada and Bukry 1980) and check alternative bioevents included in a more recent mid-latitudes biostratigraphic scheme (Fornaciari et al. 2010). Calibration ages are estimated based on the ranges of the biozones relative to a detailed magnetostratigraphy constructed for the site. Of particular biostratigraphic significance, our study shows that the Top of Sphenolithus furcatolithoides, the Base of common and continuous occurrence (Bc) of Dictyococcites bisectus and the total range of Sphenolithus obtusus can be used to better constrain the middle Eocene interval. The studied sediments cover the crucial time period that
followed maximum Cenozoic warmth and led up to the initial major glaciation on Antarctica, including two important climatic events, the Middle Eocene Climatic Optimum (MECO), a transient episode of global warming during a long-term cooling trend, and the Oi-1 event. The peculiar regime in sedimentation observed in the equatorial Pacific, which roughly consists of alternating phases of Carbonate Accumulation Events (CAE) and crashes in carbonate content, are correlated with increases and decreases in calcareous nannofossil abundances. A more detailed comparison indicates that the MECO corresponds to an interval with very low carbonate in between CAE3 and CAE4. This event is correlative with the Top of S. furcatolithoides, the Bc of D. bisectus and a prominent increase in the relative abundance of heavy calcified nannofossils (e.g., discoasters)
LA FRAMMENTAZIONE DELL'ATTIVITA' IMPRENDITORIALE IN ITALIA: PROBLEMI, ESITI E SPIEGAZIONI A PARTIRE DA UNO STUDIO DI CASO
No full textIn spite of the postwar economic development seen in most industrialized countries, in Italy, small-scale firms have become hegemonic. The diffusion of most small firms arose during the “economic miracle” and has produced many micro production systems across the country. As small firms have increased, diffusion and the strength of labor intensive specialization patterns have been explained by the theories of delayed development and backwardness or “last-comers” theories that have assigned Italy to a low position in the global value chain. Industrial process lag has often been considered the heritage of rural roots, strictly related to human relations and institutions preceding industrialization. Nevertheless, this distinctive form adopted by industrial development has filled a strategic position in promoting national economic growth.
The division of labor within firms in Italy has been associated with rapid growth in self-employment and activities related to finance and rental intermediation. Italian entrepreneurial spirit has mostly based its wealth on labor-force accessibility and State financing, which has driven the manufacturing specialization in textiles and leather products, basic metal products, and furniture. These manufacturers need a low technological outlay and a high human labor amount that can easily be portioned. The low capital investment required for enterprise start up has supported a huge increase of firms all over the country.
The State has provided a huge range of measures to decrease the production costs, including incentives for many types of firms, financial aid for areas with low socioeconomic status, interventions for exportation and trade, a special system of shock absorbers, and monetary devaluation policies. Despite the significant amount of economic analysis concerning the firm size and its transformations, only contingent research has deepened the relations between industrial structure and State regulation. Contrary to historical approaches based on backwardness late-comers or economic sociology theories of “small firms society”, this phd thesis shall attempt to investigate the central role played by national institutional laws in modeling manufacturing structure. This analysis will point out the engagement of institutions in providing huge financial aid to the growth of enterprises and regulation of specific labor relations.
Hence, the system of incentives and financing has produced a dependence attitude that has reduced the entrepreneurial hazard and the commitment to firm investment over a long-term period. Despite economic and historical explanations about Italian poor specialization and backwardness, I will show that the State contingent strategy approach, involving the replacement of industrial policies, indeed, has caused the progressive diminishing of resources to converge to innovation and research, in addition to inducing skill downgrading. The result is a circular process which is enhancing the erosion of Italian manufacturing industry and increasing the vulnerability of the economic system
Aripiprazole for the treatment of delusional disorders: A systematic review
No full textBackground: Delusional disorder is an uncommon psychotic disorder. The first-line treatments for this chronic and resistant condition are antipsychotic medications, usually associated with several side effects that can exacerbate poor adherence. Conversely, aripiprazole is a well-tolerated antipsychotic drug that is effective in the treatment of other psychotic disorders. Here, we aimed to systematically review and summarize the currently available literature to evaluate the effectiveness and tolerability of aripiprazole in delusional disorders. Methods: A comprehensive literature search from inception until February 2020 was performed in PubMed, Cochrane Database of Systematic Reviews, and Scopus databases using The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results: We identified 21 single cases of delusional disorders, mostly somatic type, treated with aripiprazole. All studies reported patient clinical improvements after the beginning of the treatment with aripiprazole. The average dose of aripiprazole was 11.1 mg/day, and the average time to achieve a clinical response was 5.7 weeks. Few adverse effects were reported, including asthenia, extrapyramidal symptoms, hyperprolactinemia, and insomnia. Conclusions: Our findings suggest that aripiprazole may be an effective treatment for delusional disorders with good tolerability. Further studies comparing aripiprazole with other antipsychotics in the treatment of delusional disorders are needed
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
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