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    Contrast enhancement issues in the MR evaluation of the central nervous system

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    Because of its high intrinsic contrast resolution, magnetic resonance imaging (MRI) has largely replaced computed tomography (CT) in the diagnosis of central nervous system (CNS) diseases, and the use of contrast media in MRI of the CNS has increased progressively, gadolinium chelates being, by far, the most used ones. Our paper will focus on the current indications for contrast-enhanced MR imaging of the CNS and will outline the current role and the future trends in contrast medium (CM) administration in the diagnosis of CNS disease. Gadolinium chelates are now routinely employed in MRI of the brain and spine and have been shown to be relatively safe and well tolerated at standard doses of 0.1 mmol/kg b. w. Although there is general consensus on the usefulness of CM administration in MRI of the CNS, some controversy still persists on the type of CM to be used, on the administration scheme, and on the imaging protocol. The current trend is toward selective employment of CM, the effect of which can be enhanced by Magnetization Transfer (MT) techniques, to increase the sensitivity of the procedure. Double or triple doses of CM can be useful in the detection of small parenchymal lesions with faint enhancement, in functional/dynamic studies of the brain parenchyma and in MR angiography. Gadoteridol (ProHance(R)) closely resembles the features of an optimal CM, because it is non-ionic, has a low osmolality and a low viscosity, and may be particularly efficacious when high doses are required

    Os odontoideum in a patient with cervical vertigo: a case report.

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    Cervical vertebral anomalies are often associated with malformations or traumas, they may be completely asymptomatic and represent an occasional finding in vertigo or can cause severe neurologic complications (ie, compression of the upper cervical spine with myelop- athy, epilepsy, or respiratory failure). This clinical case is a patient who came to us for observation for a peripheral harmonic vestibular syndrome, and in whom a malformation of the cervical vertebral joint (os odontoideum) was occasionally found on magnetic resonance imagin

    DIAGNOSTIC IMAGING INFORMATION SYSTEMS: DREAM. REPORTING MANAGEMENT

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    From the clinical standpoint, the report represents the synthesis of the diagnostic process and it is the central activity of radiology. However, reporting cannot be separated from the entire organizational cycle inside the Diagnostic Imaging Department as well as within the structure as a whole. The effectiveness of the contribution an information system can give to the radiologist is related to the information and functional integration of the various applications operating in the hospital and over the territory. Based on these considerations, the main types of support the information tool can offer, are reported together with the primary objectives which were basic to the development of the reporting module within the DREAM system and the major solutions adopted to facilitate the attainment of these objectives

    Endoscopic treatment and radiotherapy of a skull base chondrosarcoma in a patient with type II enchondromatosis

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    Maffucci syndrome is a rare, congenital mesenchymal displasia characterized by multiple enchondromata and hemangiomata, both of which can undergo malignant transformation. Intracranial involvement is uncommon. There is no medical treatment for enchondromatosis. Surgery is indicated in case of complications (pathological fractures, severe functional defects, malignant transformation). Here, we describe a large chondrosarcoma involving nose, paranasal sinuses and clivus treated by endoscopic transnasal resection and radiotherapy, in a 25‐year‐old patient with Maffucci’s syndrome

    Spinal cord stimulation prevents the effects of combined experimental ischemic and traumatic brain injury - An MR study

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    Spinal cord stimulation (SCS) interferes with cerebral blood flow (CBF). In this paper we try to evaluate the possible preventing effect of SCS in an animal model of combined ischemic and traumatic injury. We studied 20 New Zealand rabbits undergoing ligature of both carotid arteries and a right hemispheric craniectomy and about 3 h mechanical injury (200 mg) over the dura. In 10 animals (control group) SCS was not delivered; in 10 (SCS group) cervical SCS was started 20 min after arterial ligation and before the craniectomy and the mechanical injury. MR examination was performed in all the animals at the end of the experiments. Compared to the control group none but one of the SCS showed lesional pattern far from the craniectomy suggesting a 'preventing' effect of SCS on the secondary damage associated with our model combined ischemic and traumatic brain injury. Copyright (C) 2002 S. Karger AG, Basel
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