369 research outputs found
An Investigation of Aural Space inside Mousa Broch by Observation and Analysis of Sound and Light
No full textThis project emphasises the unique character and construction of Mousa broch, questions the model of Mousa broch as a roofed home (an interpretation adopted by Historic Scotland in 2002) and considers the way in which sound and light informs our understanding of the spaces contained within its structure. Underpinning the approach to data collection was the architectural concept of aural space. The author attempts to convey an impression of aural space inside Mousa broch by the creation of an audio-visual record supported by acoustic analysis, archaeological discussion, and an architectural breakdown of the spaces within the broch structure. Audio recordings, sound samples, photographs and movies were made on Mousa island and inside Mousa broch during the period of the Summer solstice of 2009
Author Correction: the Influence of Nano Filter Elements on Pressure Drop and Pollutant Elimination Efficiency in Town Border Stations
No full textThe original version of this Article contained an error in the order of the author names, which was incorrectly given as Hamed Ebadiyan, Saeed Zeinali Heris, Seyed Borhan Mousavi, Shamin Hosseini Nami ; Mousa Mohammadpourfard. Consequently, in the Author Contributions section, “H.E. Investigation. S.Z.H. Supervision, Conceptualization, Methodology, Validation. S.B.M. Formal analysis, Writing original draft. S.H.N. Formal analysis, Writing original draft. M.M. Validation.” now reads: “S.Z.H. Supervision, Conceptualization, Methodology, Validation. H.E. Investigation. S.B.M. Formal analysis, Writing original draft. S.H.N. Formal analysis, Writing original draft. M.M. Validation.” The original Article has been corrected. © 2023, The Author(s)
EVALUATION OF MORPHINE, CODEINE AND D-PROPOXYPHENE IN RATS UTILIZING PHARMACOLOGICAL DATA OBTAINED FROM AN OPTIMIZED ANALGESIA TESTER
No full textThe applicability of the molecular scale drug entrapment concept for improving the action of morphine, codeine, and d-propoxyphene was investigated. Seven different methods of interacting the analgetic drugs with methacrylate-methacrylic acid copolymer latices were evaluated in vitro and in vivo. For in vivo assessment of the products, drug-polymer interaction and dissolution studies were conducted. Dissolution testing was accomplished using a multi-channel continuous flow apparatus which was standardized by investigating the effects of days, dissolution cells, flow rates, and sample sizes on the release profiles of the products. Subsequently, the apparatus was used to determine the effect of the drug concentration used to prepare a product and the effect of the product\u27s particle size on its release profile. Both effects were found to be influential on a product\u27s in vitro performance. The reslts from the dissolution testing, in agreement with the drug-polymer interaction studies, indicated that the products investigated had an extremely low affinity to interact with the polymer. For in vivo evaluation of the drug-polymer products, a light-beam tail-flick tester was employed. Principles of statistical design and optimization were utilized to increase the reliability and reduce the variability of this thermal technique in evaluating analgetic drugs in test animals (rat tail-flick response). The light-beam technique was compared against the more conventional hot-wire method by in vitro (temperature profiles) and in vivo (analgetic response profiles) evaluations, both of which showed the advantages and superior performance of the former over the latter. The utility of this analgesia tester accompanied by appropriate data collection (reaction time) and response variable expression (response intensity) in reducing the problems associated with data treatment was demonstrated. This analgesia tester was then used to evaluate the drug-polymer interacted systems in vivo. Results showed that the products studied did not offer any prolongation of analgetic activity. The data obtained from the optimized analgesia tester and the standardized dissolution testing procedure corroborated each other and thus resulted in reliable in vitro - in vivo correlations for the drug-polymer interacted systems. . . . (Author\u27s abstract exceeds stipulated maximum length. Discontinued here with permission of school.) UM
SYNTHESIS OF C-GLYCOSYL AMINO ACIDS AS STABLE BUILDING BLOCKS FOR MODIFIED GLYCOPEPTIDE SYNTHESIS
No full textIn this thesis, we have studied and synthesized new class of C-glycosly amino acids whose structure features a
hetrocycle ring holding the carbohydrate and the amino acid fragments. Pyridine and tetrazole rings were used as
hetrocycle linkers in this project. This class of C-glycosyl amino acids is of interest as new chealtors and as building
building blocks for cotranslational glycopeptides synthesis. In the first part, C-Glycosylmethyl pyridylalanines were
synthesized via thermally induced Hantzsch-type cyclocondensation using an aldehyde-ketoester-enamino ester system.
To one of these reagents was attached a C-glycosyl residue, while to another was bound an amino acid fragment. In a
one-pot optimized methodology, the dihydropyridine was not isolated while its purification was carried out by removal
of unreacted material and side products using polymer-supported scavengers. Then the dihydropyridine (mixture of
diastereoisomers) was oxidized by a polymer-bound oxidant to give the target pyridine bearing the two bioactive
residues. In this way, a range of eight compounds (58-68% yield) was prepared in which the elements of diversity were
(i) the gluco and galacto configurations of the pyranose ring, (ii) the α- and β-configurations at the anomeric center, and
(iii) the positions of the carbohydrate and amino acid sectors in the pyridine ring. The orthogonal functional group
protection in these amino acids allowed their easy incorporation into oligopeptides via sequential amino and carboxylic
group coupling.
In the second part, tetrazole moiety was constructed via Huisgen 1,3-dipolar cycloaddition between nitriles and organic
azides. Two sets of compounds have been prepared, one being constituted of C-galactosyl and C-ribosyl O-tetrazolyl
serines, while the other contains S-tetrazolyl cysteine derivatives. In both cases, the synthetic scheme involved a twostep
route: the first one being the thermal cycloaddition of a sugar azide with p-toluensulfonyl cyanide (TsCN) to give a
1-substituted 5-sulfonyl tetrazole and the second the replacement of the tosyl group with a serine or cysteine residue.
For the high efficiency and operational simplicity, the azide-TsCN cycloaddition appears to be a true click process.
Finally, one of the amino acids prepared was incorporated into a tripeptid
Lyapunov-Based Model Predictive Control for Stable Operation of a 9-Level Crossover Switches Cell Inverter in Grid Connection Mode
No full textThis study proposes the application of a Lyapunov-based Model Predictive Control (L-MPC) approach to a 9-level Crossover Switches Cell (CSC9) converter operating in grid connection mode. The proposed method utilizes the structure of the classical finite-control-set MPC (FCS-MPC) technique while integrating a cost function that requires no tuning. By deriving the cost function based on Lyapunov theory, the system stability is ensured. Notably, the suggested approach offers several advantages over traditional MPC controllers. Firstly, it eliminates the need for gain tuning, thereby simplifying the implementation process. Secondly, the proposed controller prioritizes stability as a key design aspect. The presented simulation results prove that the proposed controller effectively regulates the voltage of the DC capacitor around its desired value and feed a smooth sinusoidal current to the grid with low total harmonic distortion (THD) while operating at a unity power factor.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.DC systems, Energy conversion & Storag
A benchmark study of the multiscale and homogenization methods for fully implicit multiphase flow simulations
No full textAccurate simulation of multiphase flow in subsurface formations is challenging, as the formations span large length scales (km) with high-resolution heterogeneous properties. To deal with this challenge, different multiscale methods have been developed. Such methods construct coarse-scale systems, based on a given high-resolution fine-scale system. Furthermore, they are amenable to parallel computing and allow for a-posteriori error control. The multiscale methods differ from each other in the way the transition between the different scales is made. Multiscale (finite element and finite volume) methods compute local basis functions to map the solutions (e.g. pressure) between coarse and fine scales. Instead, homogenization methods solve local periodic problems to determine effective models and parameters (e.g. permeability) at a coarser scale. It is yet unknown how these two methods compare with each other, especially when applied to complex geological formations, with no clear scale separation in the property fields. This paper develops the first comparison benchmark study of these two methods and extends their applicability to fully implicit simulations using the algebraic dynamic multilevel (ADM) method. At each time step, on the given fine-scale mesh and based on an error analysis, the fully implicit system is solved on a dynamic multilevel grid. The entries of this system are obtained by using multiscale local basis functions (ADM-MS), and, respectively, by homogenization over local domains (ADM-HO). Both sets of local basis functions (ADM-MS) and local effective parameters (ADM-HO) are computed at the beginning of the simulation, with no further updates during the multiphase flow simulation. The two methods are extended and implemented in the same open-source DARSim2 simulator (https://gitlab.com/darsim2simulator), to provide fair quality comparisons. The results reveal insightful understanding of the two approaches, and qualitatively benchmark their performance. It is re-emphasized that the test cases considered here include permeability fields with no clear scale separation. The development of this paper sheds new lights on advanced multiscale methods for simulation of coupled processes in porous media.Reservoir EngineeringNumerical Analysi
The Challenges of Securing Cloud Multitenant Design
No full textAbstract: Multitenant architecture is the foundational model for cloud computing model in public cloud providers, in addition to on-premise enterprise level software stack. However, this model can poses security risks to organizations, which requires good security architecture design , and understanding. In addition, it will require cybersecurity expertise in cloud native architecture, and the on-going challenge to ensure "ISOLATION" among co-hosted resources to maintain cybersecurity posture and data protection.
Keywords: Cloud, Cloud Security, Database, Database Security, Cybersecurity, Multitenant Architecture, Cloud Native Architecture.
Title: The Challenges of Securing Cloud Multitenant Design
Author: Emad Al-Mousa
International Journal of Computer Science and Information Technology Research
ISSN 2348-1196 (print), ISSN 2348-120X (online)
Vol. 11, Issue 3, July 2023 - September 2023
Page No: 120-124
Research Publish Journals
Website: www.researchpublish.com
Published Date: 25-August-2023
DOI: https://doi.org/10.5281/zenodo.8283155
Paper Download Link (Source)
https://www.researchpublish.com/papers/the-challenges-of-securing-cloud-multitenant-designInternational Journal of Computer Science and Information Technology Research, ISSN 2348-1196 (print), ISSN 2348-120X (online), Research Publish Journals, Website: www.researchpublish.co
Frequency Unification Theory
No full textA Wave-Based Model for Unifying Fundamental Forces and Spacetime
Frequency Unification Theory: A Wave-Based Model for Unifying Fundamental Forces and Spacetime
Author: Ahmed Mohamed Mousa Mohamed Moawad
Abstract
This paper introduces the Frequency Unification Theory, a novel theoretical framework that aims to unify the fundamental forces of nature—gravitational, electromagnetic, weak nuclear, and strong nuclear—through a single wave-based perspective. It proposes that spacetime itself is an emergent property of oscillatory dynamics, where both space and time are manifestations of frequency and directionality. Quantum entanglement is reinterpreted as a result of mirrored wave-phase inversions across a multidimensional oscillatory field. The model integrates relativistic and quantum effects by treating matter, energy, and force as modulations of a unified frequency continuum. The paper also presents a generalized wave equation and suggests a method for incorporating directional frequency gradients as a means of describing both curvature and interaction. This approach potentially resolves key paradoxes in both quantum mechanics and general relativity.
Keywords
unified field theory, quantum entanglement, frequency model, spacetime unification, Ahmed Moawad
Main Theoretical Framework
The core idea is that all known interactions are harmonic distortions within a multidimensional frequency lattice. Time and space are not fundamental, but rather perceived outcomes of oscillation and directional interference. Particles are treated as localized wave nodes, and their properties depend on the phase relationships in the oscillatory matrix. This leads to a new interpretation of quantum entanglement as a shared phase structure across wave inversions in a reflected manifold. The theory introduces a master equation integrating gravitational and quantum effects through a unified oscillatory function:
Ψ(x,t) = A * sin(ω_xt ± φ) + B * cos(ω_st ± θ)
Where ω_xt represents spatial-temporal frequency, ω_st the phase shift in spacetime, and (φ, θ) are directional phase constants.
Further exploration includes discussion on unification symmetry, scale modulation, and experimental implications for detecting multi-spectral interference patterns in high-energy environments
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