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Synthesis of the Furan Nucleus Promoted by Ytterbium Triflate
Full text linkAn efficient synthesis of differently substituted furans from acetylene dicarboxylates and β-dicarbonyl compounds is described. The furan nucleus was built by means of an Yb(OTf)3 catalyzed cycloaddition reaction yielding desired adducts in 91%-98% yield
Complexes of Lapachol and Lawsone with Lanthanides
Full text linkNaturally occurring 2-hydroxy-1,4-naphthoquinones are well known to form readily stable complexes with transition metals. In this short communication we describe for the first time the synthesis and preliminary data about structural characterization of complexes between two naturally widespread 2-hydroxy-1,4-naphthoquinones, namely lapachol (1) and lawsone (2), with selected lanthanides like lanthanum, gadolinium, and ytterbium. When tested as cytotoxic compounds, such complexes exhibited an activity that was either higher or equal to that of the parent naphthoquinone
Recent developments in the pharmacology of prenylated xanthones
No full textPrenylated xanthones are secondary metabolites that are particularly common in plants belonging to the Clusiaceae family. Such compounds have been the focus intensive research because of their potential as biologically active agents. Here, we survey data published over the past decade relating to the properties of prenylated xanthones to provide a more detailed view of the potential of these naturally occurring compounds as therapeutic agents
A green chemical synthesis of coumarin-3-carboxylic and cinnamic acids using crop-derived products and waste waters as solvents
No full text4'-Geranyloxyferulic Acid: an Overview of its Potentialities as an Anti-cancer and Anti-inflammatory Agent
No full textQuantification of 4'-Geranyloxyferulic Acid (GOFA) in Honey Samples of Different Origin by Validated RP-HPLC-UV Method
No full textNatural honey has been employed as a nutraceutical agent with benefits and therapeutic promises for humans for many centuries. It has been largely used as food and medicine by all generations, traditions, and civilizations, both ancient and modern. Several chemicals having beneficial effects for human health have been reported as components of natural honey and these include sugars, organic acids, aminoacids, minerals, and vitamins. Also some important phytochemicals have been described and these comprise tannins, flavonoids, terpenes, saponins, and alkaloids. In this note it is described the successful application of a RP HPLC-UV-vis method for the separation and quantification of 4'-geranyloxyferulic acid (GOFA) in four honey samples of different origin. Concentration values showed a great variation between the four samples tested, being chestnut honey the one richest in GOFA (7.87 mg/g). The findings described herein represent the first example reported in the literature of the characterization of an oxyprenylated phenylpropanoid in honey
HPLC analysis of selected prenyloxycinnmaic acid derivatives oxidized in the side chain in extracts of grapefruit seeds
No full textHPLC analysisi of selected prenyloxyphenylpropanoids in extracts of grapefruit seeds, honey, and propolis
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