1,720,964 research outputs found
SEASONAL VARIATION OF SOME HAEMATOLOGICAL PARAMETERS IN DIFFERENT AUTOCHTHONOUS ITALIAN BEEF-CATTLE BREEDS
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Liver function evaluation in dogs by the galactose load test.
No full textDynamic tests consists in administration of substances metabolised by the liver and in the subsequent study of their kinetics in order to provide quantitative indications about specific hepatic metabolic functions. The aim of the study is to verifiy the reliability of the application of the galactose load test in dogs an to compare the concentration-time curves in healthy animals with those obtained in patients with liver disease. 500 mg/kg of a 30% w/v galactose solution was administred e.v to 5 healthy dogs and to 5 patients with liver disease. Blood samples were collected every 10 minutes until 90 min after injection and serum galactose concentration was determined with an enzimatic method. Serous values for hepathopatic dogs over the T40-T90 period were higher than mean curve values of control dods in 4 out of 5 animals. Further investigations are needed in order to evaluate effective diagnostic and progostic reliability of this test
Il test del galattosio nello studio delle patologie epatobiliari nel cane: aspetti preliminari
No full textImpiego della densitometria ossea a doppia energia a raggi X ( Hologic QDR - 1000) nella Diagnostica Clinica Veterinaria. Indagine preliminare
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Relationship between exercise capacity and front hoof longitudinal balance in horses
No full textTo the authors' knowledge, the effect of hoof balance alteration on exercise capacity or performance has not been investigated. With the aim of evaluating the relationships between longitudinal front hoof balance and exercise capacity (lactate vs. speed relationship, run time and stride characteristics), two experiments were undertaken. In the first test the horses, left unshod, performed an incremental speed test in which parameters chosen to evaluate exercise capacity were related to hoof longitudinal balance. In the second part of the study the same group of horses had the length of the toe altered (decreased and increased) with the application of shoes, while the angle of the foot and the height of the foot from the ground remained the same. The relative change in exercise capacity due to the alteration of longitudinal balance was observed. In the unshod experiment, lactate level at the speed of 10 ms-1 (5.0±2.0 mmoll-1) was significantly associated with the angles DC° (angle described by the dorsal cortex with respect to the ground; 50.0±3.2°) and PC° (angle described by the palmar cortex with respect to the ground; 29.6 ± 2.9°), while run time (14.07 ± 1.44 min) was associated with breakover indices (Breakover index1 0.33±0.03; Breakover index2 0.30 ± 0.04 – all values mean ± standard deviation (SD)) (breakover indices were created to express the distance between the point of the toe and the point of the third phalanx relative to the length of the palmar cortex or relative to the distance between the point of the third phalanx and the centre of rotation of the distal interphalangeal joint). These associations have to be judged cautiously because the influence of hoof balance on exercise capacity could be biased by other physiological factors and because hoof balance parameters themselves could reflect the conformation of other anatomical structures far from the phalanges. The selective alteration of front hoof balance in the second part of the study produced a significant difference in blood lactate level only at 6 ms-1 (mean ± SD: La6?m?s-1 0.32 ± 0.39 mmoll-1), with this benefit in terms of lactate level being associated with an increase in stride length (mean ± SD: ΔSL6ms-1 0.01 ± 0.05 m; ΔSL10ms-1 0.112 ± 0.218 m). In conclusion, while higher exercise capacity seemed to be associated with lower DC°, PC° and breakover indices, decreasing the toe length without altering the foot angle was beneficial only in terms of lactate level at the speed of 6 ms-1 for horses with DC° greater than 45°; this benefit was accompanied by a slight lengthening of the stride at both 6 and 10 ms-
Il test del galattosio nello studio delle patologie epato-biliari del cane
No full textL'approccio diagnostico alle epatopatie del cane permette di evidenziare il danno cellulare, l'insufficienza funzionale e di individuare la patologia sottostante, ma non consente una accurata valutazione della funzionalità residua epatica e della sua evoluzione nel tempo. A questo scopo in medicina umana sono stati a lungo utilizzati dei test dinamici (o funzionali) e il test del galattosio è uno di questi: esso consiste nella somministrazione dello zucchero in bolo endovenoso e nello studio della sua cinetica di eliminazione. Obiettivo di questo lavoro è stato quello di verificare l'applicabilità nel cane di una metodica presa dalla medicina umana, e di studiare la curva di eliminazione del galattosio dopo la sua somministrazione. Le determinazioni sono state effettuate contemporaneamente su siero, plasma-EDTA e spot di sangue intero su carta bibula. L'analisi statistica delle curve ottenute he permesso di individuare due intervalli: il primo, compreso nei 40 minuti successivi alla somministrazione, risulta poco interessante dal punto di vista statistico; un secondo intervallo, tra i 40 e i 90 minuti dal'iniezione, può essere rappresentato in modo significativo da una curva polinomiale quadratica per le matrici siero e plasma, e pertanto sembra promettere interessanti sviluppi per lo studio delle malattie epatobiliari del cane
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