145 research outputs found
Differential association of two PTPN22 coding variants with Crohn's disease and ulcerative colitis.
No full textDiaz-Gallo, L.-M., Espino-Paisán, L., Fransen, K., Gõmez-García, M., Van Sommeren, S., Cardeña, C., Rodrigo, L., Mendoza, J.L., Taxonera, C., Nieto, A., Alcain, G., Cueto, I., Lõpez-Nevot, M.A., Bottini, N., Barclay, M.L., Crusius, J.B., Van Bodegraven, A.A., Wijmenga, C., Ponsioen, C.Y., Gearry, R.B., Roberts, R.L., Weersma, R.K., Urcelay, E., Merriman, T.R., Alizadeh, B.Z., Martin, J
The flower of kings : a study of the Arthurian legend in England between 1485 and 1835
No full textThis book provides for the first time in over seventy-five years a single, comprehensive, up-to-date account of the fortunes of the Arthurian story in England from the time of Malory to the beginning of the Victorian period. After a brief survey of the earliest forms of the legend, the author examines the slow decline of the myth in the English Renaissance until its near extinction by the middle of the eighteenth century, despite the attraction which it held for Spenser, Drayton, Jonson, and Dryden. Succeeding chapters show that even through the legend's vitality was reduced by both Dryden and Fielding, the Romantic movement brought Arthur back to life, Minor figures such as William Hilton and Richard Hole, together with Scott and Wodsworth, though they did not produce great poems on the subject, are shown nevertheless to have responded seriously to the legend. The book concludes with an England ready in its interests and sympathies for the great flowering of the Arthurian story among the Victorians. Throughout this survey, which covers both the major figures and a number of hitherto unexamined minor authors, James D. Merriman is concerned with several questions of considerable interest both scholarly and critical
Because We Are Poor: Irish Theatre in the 1990s
No full textThroughout the twentieth century, Irish theatre was fully engaged with the pressing questions of independence – how to achieve it, and how the gap between what was desired and what was settled for might be addressed. In Because We Are Poor, Victor Merriman reads Ireland’s postcoloniality as a state of critical desire for a postponed project of decolonisation in Independent Ireland. He develops insights from Awam Amkpa, Luke Gibbons, Peadar Kirby, Joe Lee, David Lloyd and others to argue that Irish theatre is staged in a neo-colonial social order, dominated by economic analyses and public policies designed to secure the position of indigenous elites, usually at the expense of the majority of Irish people. Theatre emerges as a key site in which the contradictions arising from frustrated but enduring desires are embodied, enacted and enabled. During the 1990s, the state’s monopoly on public discourse in Independent Ireland comes under severe pressure, with hitherto marginal concerns appropriating public space and demanding to be heard. Irish theatre responds to the range and diversity of those voices, to the extent that the Review of Theatre in Ireland (1995-1996) envisages a National Theatre in dialogue with a Theatre of the Nation. The expanded theatrical activity of the 1990s is the focus of Because We Are Poor, and the author’s intimate involvement in that moment, as scholar, practitioner, and policy-maker makes the analysis offered here especially compelling. This book brings together concerns which the author has worked to articulate in Irish theatre criticism. It critiques contemporary appropriations of the postcolonial, or post-colonial, among scholars of Irish drama, and proposes a nuanced postcolonial critical practice, challenging critical vocabularies applied to Irish drama. The book addresses the role, crises and potential of Irish theatre, as the cultural and political consequences of globalisation manifest themselves
Maternal Smoking during Pregnancy Is Associated with Offspring Hypodontia
No full text Little is known about environmental risk factors for hypodontia. The objective of this study was to investigate the association between hypodontia and common environmental risk factors, such as maternal smoking and alcohol and caffeine consumption during pregnancy. Eighty-nine hypodontia cases with 1 or more missing permanent lateral incisors and/or 1 or more missing premolars were enrolled in this clinic-based case-control study. Some 253 controls with no missing teeth were frequency matched to cases by age and sex. Hypodontia was diagnosed using panoramic radiographs. Sociodemographic data were collected from both the participants and their mothers, with maternal self-reported active and passive smoking, as well as alcohol and caffeine consumption during pregnancy, assessed by a questionnaire. Odds ratios (ORs) and their 95% confidence intervals (CIs) were calculated with logistic regression to assess the strength of association between risk factors and hypodontia. OR estimates were then adjusted for possible confounders, such as maternal age at delivery, sex and gestational age of the child, and household socioeconomic background. Significant associations were found between hypodontia and maternal cigarette use during pregnancy, as well as the number of cigarettes smoked per day. The consumption of 10 or more cigarettes per day during pregnancy was associated with greater odds of having a child with hypodontia (adjusted OR, 4.18; 95% CI, 1.48–11.80; P = 0.007). Observed associations between hypodontia, second-hand smoke, and alcohol and caffeine consumption were not statistically significant. Maternal smoking during pregnancy is associated with hypodontia. Larger samples and prospective observational study designs, however, are needed to investigate this association further. </jats:p
Woodswoman walking: a journey toward solitude
No full text2014 Summer.On September 1, 2013, Joannah Merriman, not at all a hiker, not really an outdoor athlete of any sort, set out to walk the Camino de Santiago from the French Pyrenees to Santiago de Compostela. A card-carrying member of AARP, armed with a passport, a camera, a journal, and a deep desire to find solitude for longer than a day or a week, she began an 800 kilometer "walk" along the Camino Frances, alone and with the many other peregrinos who happened to be on the path during that time period. Throughout the six weeks of her personal journey, she discovered that the walk was much more difficult than she had imagined, and that she was much stronger than she had ever thought she might be. She met and embraced the Spanish countryside, her fellow trekkers, gratitude for a bed at night, sometimes in a room with up to a hundred fellow pilgrims, and most important, herself
Graph MBO on Star Graphs and Regular Trees.: With Corrections to DOI 10.1007/s00032-014-0216-8
No full textThe graph Merriman–Bence–Osher scheme produces, starting from an initial node subset, a sequence of node sets obtained by iteratively applying graph diffusion and thresholding to the characteristic (or indicator) function of the node subsets. One result in [14] gives sufficient conditions on the diffusion time to ensure that the set membership of a given node changes in one iteration of the scheme. In particular, these conditions only depend on local information at the node (information about neighbors and neighbors of neighbors of the node in question). In this paper we show that there does not exist any graph which satisfies these conditions. To make up for this negative result, this paper also presents positive results regarding the Merriman–Bence–Osher dynamics on star graphs and regular trees. In particular, we present sufficient (and in some cases necessary) results for the set membership of a given node to change in one iteration.Mathematical Physic
Correction to: Trans-ancestral dissection of urate- and gout-associated major loci SLC2A9 and ABCG2 reveals primate-specific regulatory effects
No full text© 2020, The Author(s), under exclusive licence to The Japan Society of Human Genetics. The original version of this article unfortunately contained a mistake. One of members of Eurogout consortium wasn’t included. The corrected version is given below. Eurogout consortium A. Abhishek, M. Andres, T. Crisan, N. Dalbeth, M. Doherty, L. Jacobsson, M. Janssen, T.L. Jansen, L.A. Joosten, M. Kapetanovic, F. Lioté, H. Matsuo, G. McCarthy, T. Merriman, F. Perez-Ruiz, P.L. Riches, P. Richette, P.C. Robinson, E. Roddy, B. Stiburkova, A. So, L.K. Stamp, A.K. Tausche, R. Torres-Jiminez, T. Uhlig
Beeman, Plain, Honest Men - The Making of the American Constitution
No full text Richard Beeman's work examines, as the title suggests, how the Constitution was made. It is authoritatively researched, as the author surveyed Madison's writings, those of other contributors, and The Federalist Papers, as well as consulting many other sources. The purpose is twofold: first, to humanize that founding document. Instead of describing it as a "miracle from Philadelphia," as Catherine Drinker Bowen did, Beeman views it more as the work of men. He uses a quotation of Gouverneur Morris for his title, and so himself is not calling the Founding Fathers plain or ordinary. However, if forced to choose between man and god to describe the founders, Beeman, long-time professor at the University of Pennsylvania and author of multiple books, clearly would choose man. Beeman's second purpose is to wade into the debate about how we interpret the Constitution. This is not in terms of what any specific provision means, but more how certain we can be about how the Founding Fathers (or the founding generation) understood any provision. He argues that it is difficult to tell what they thought would actually happen and notes how many of the provisions were arrived at quickly with little discussion. For instance, the "necessary and proper" clause was agreed to swiftly with no dissenting vote. Thus, about all the current generation can tell is that everyone might have agreed on the meaning, but there is little to tell what that meaning was. He also points out that little discussion was done at the ratification conventions and that various states had external reasons to adopt the Constitution, and so they focused on that (whether or not to join) rather than what the Constitution meant. Turning to The Federalist Papers, he notes that these were more "political propaganda aimed at persuading undecided voters to support the Constitution" than "high-minded political theory." Thus, interpreting them as exactly what the Constitution meant at the time is problematic
L'image de la police parisienne sous les monarchics censitaires (1814-1848) : the image of the police of Paris during the Constitutional Monarchy (1814-1848)
No full textThis thesis was scanned from the print manuscript for digital preservation and is copyright the author.
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