44 research outputs found
Number of Transmitted/Founder (T/F) viruses.
<p><sup>A</sup>Minimum estimates of the number of T/F viruses for 7B2 IgG and palivizumab IgG treated rhesus macaques are shown. At a mean of 60 sequences per animal, there is 95% confidence that all variants that are >5% in prevalence have been enumerated.</p><p>*The difference in T/F variants between the 7B2 IgG_AAA treated animals and the negative control animals palivizumab IgG was statistically significant, p = 0.01; Mann-Whitney rank sum test, two tailed.</p><p><sup>B</sup> Minimum estimates of the number of T/F viruses for A32 IgG_AAA mAb and palivizumab IgG mAb treated rhesus macaques are shown. At a mean of 37 sequences per animal, there is 95% confidence that T/F variants with >8% prevalence in the population are represented.</p><p>*The difference in T/F variants between the A32 IgG_AAA treated animals and the negative control animals palivizumab IgG was statistically significant, p = 0.033; Mann-Whitney rank sum test, two tailed. <sup>C</sup> Minimum estimates of the number of T/F viruses for CH22 IgG_AAA mAb and CH65 IgG mAb treated rhesus macaques.</p><p>*The difference in T/F variants between the CH22 IgG_AAA treated animals and the negative control animals CH65 IgG was statistically significant, p = 0.011; Mann-Whitney rank sum test, two tailed.</p><p>Number of Transmitted/Founder (T/F) viruses.</p
Interference study of the chi c0(13P0) in the reaction -pp-->pi0pi0.
Fermilab experiment E835 has observed (-)pp annihilation production of the charmonium state chi(c0) and its subsequent decay into pi(0)pi(0). Although the resonant amplitude is an order of magnitude smaller than that of the nonresonant continuum production of pi(0)pi(0), an enhanced interference signal is evident. A partial wave expansion is used to extract physics parameters. The amplitudes J=0 and 2, of comparable strength, dominate the expansion. Both are accessed by L=1 in the entrance (-)pp channel. The product of the input and output branching fractions is determined to be B((-)pp-->chi(c0))xB(chi(c0)-->pi(0)pi(0))=(5.09+/-0.81+/-0.25)x10(-7)
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Absolute X-Ray Yields from Laser-Irradiated, Ge-doped Aerogel Targets
Bright, multi-keV x-ray sources are essential for radiography of inertial-confinement fusion (ICF) experiments. In this context, there are two parameters of importance: the energy of the emitted photons, which determines how penetrating the x-rays are for radiographic purposes, and the brightness of the source, which determines the ability of a radiograph to resolve small features. As ICF experiments continue to get larger, such as those that will be carried out at the National Ignition Facility at Lawrence Livermore National Laboratory, or at the French Commissariat a l'Energie Atomique's (CEA) Laser MegaJoule, and compression in fuel capsules gets higher, sources for x-ray backlighting will have to have harder-photon spectra. For a given laser energy available to drive the multi-keV x-ray-backlight source, the only way for the source to get brighter is for it to convert the laser to x-rays more efficiently. We have been developing and characterizing laser-driven, underdense x-ray sources that are highly efficient in recent years [2-5]. CEA researchers have also recently had great success efficiently making multi-keV x-rays from pre-pulsed foils [6]
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Use of Lasers to Study the Impact of Fractionation and Condensation on the Toxicity of Nuclear Weapon Fallout
An experimental concept has been developed to collect data to aid in the refinement of simulation programs designed to predict the fallout effects arising from surface and shallowly buried nuclear weapon detonations. These experiments, called the Condensation Debris Experiments (CDE), are intended to study the condensation/fractionation of material that is liberated following an initial deposition of laser energy onto a small, characterized target. The CDE effort also encompasses target development and material studies as well as supporting computational efforts studying radiation hydrodynamics, computational fluid dynamics, and relevant neutron activation processes (not discussed here)
E835 at FNAL: Charmonium Spectroscopy in p̄p Annihilations
E835 studied the properties of the charmonium states formed in pp̄ annihilations. Recent and preliminary results are presented, including new preliminary measurements of χ cJ masses and widths (improving the knowledge of fine splitting of P states), a preliminary measurement of ψ(2S) branching ratios, and of the two photon partial width of the χ c 0
Measurement of the branching ratios ψ′ → e<sup>+</sup>e <sup>-</sup>, ψ′ → J/ψππ, and ψ′ → J/ψη
We have measured several branching ratios for ψ′ decay using the data collected by the FNAL E835 experiment during the year 2000, obtaining B(ψ′ → e+e-) = 0.0068 ± 0.0001 ± 0.0004, B(ψ′ → J/ψπ+π-) = 0.292 ± 0.005 ± 0.018, B(ψ′ → J/ψπ0π0) = 0.167 ± 0.005 ± 0.014, and B(ψ′ → J/ψη) = 0.028 ± 0.002 ± 0.002. We also present a measurement of the dipion mass distribution in the decays ψ′ → J/ψππ. © 2005 The American Physical Society
Study of p̄p→ two neutral pseudoscalar mesons at the χc0(13P0) formation energy
Fermilab experiment E835 has studied reactions p̄p→π0π0, π0η,ηη, π0η′ and ηη′ in the energy region of the χc0(13P0) from 3340MeV to 3470MeV. Interference between resonant and continuum production is observed in the π0π0 and ηη channels, and the product of the input and output branching fractions is measured. Limits on resonant production are set for the π0η and π0η′ channels. An indication of interference is observed in the ηη′ channel. The technique for extracting resonance parameters in an environment dominated by continuum production is described. © 2005 The American Physical Society
Viral loads and CD4 T cell counts following high dose SHIV BaL rectal challenge in rhesus macaques passively infused with 7B2 IgG_AAA, A32 IgG_AAA or CH22 IgG_AAA.
<p><b>(A)</b> Plasma viral RNA levels and (<b>B)</b> CD4 T cell counts in 7B2 IgG_AAA and palivizumab IgG treated rhesus monkeys following challenge with SHIV-BaL. (<b>C</b>) Plasma viral RNA levels and (<b>D</b>) CD4 counts in A32 IgG_AAA mAb and control palivizumab IgG mAb passively infused rhesus monkeys following challenge with SHIV-BaL. (<b>E)</b> Plasma viral RNA levels and (<b>F)</b> CD4 Counts in rhesus monkeys following challenge with SHIV-BaL after passive administration of CH22 or CH65 IgG mAbs.</p
Measurement of the angular distribution in (p)over-barp ->psi(2S)-> e(+)e(-)
We present the first measurement of the angular distribution for the exclusive process (p) over barp -> psi(2S) -> e(+)e(-) based on a sample of 6844 events collected by the Fermilab E835 experiment. We find that the angular distribution is well described by the expected functional form d N/d cos theta* proportional to 1 + lambda cos(2) theta*, where theta* is the angle between the antiproton and the electron in the center of mass frame, with lambda = 0.67 +/- 0.15(stat) +/- 0.04(sys). The measured value for lambda implies a small but non-zero psi(2S) helicity 0 formation amplitude in (p) over barp, comparable to what is observed in J/psi decays to baryon pairs
