1,882 research outputs found
Dynamical Wilson fermions and the finite temperature transition in lattice QCD
Barbour I, Laermann E, Lippert T, Schilling K. Dynamical Wilson fermions and the finite temperature transition in lattice QCD. 1991
Nucleation and growth of epitaxial La1-xCaxCoO3-δ films on single crystalline substrates by pulsed reactive crossed-beam laser ablation
Nucleation and growth of epitaxial La1-xCaxCoO3-delta films on single crystalline substrates by pulsed reactive crossed-beam laser ablation / A. Weidenkaff ... - In: Symposium on Photonic Processing of Surfaces, Thin Films and Devices «2003, Strasbourg»: Proceedings of ... / ed. T. K. Lippert ... - Amsterdam u.a. : Elsevier, 2004. - S. 406-410. – (Thin solid films ; 453/454
Human T lymphocytes and mast cells differentially express and regulate extra- and intracellular CXCR1 and CXCR2
CXCL8 plays a major role in cell recruitment to sites of inflammation. Apart from neutrophils, little is known, however, about the cellular distribution and regulation of CXCL8 receptors in cells involved in acquired and adaptive immune responses. In previous studies, we have demonstrated the extracellular expression and function of CXCR1/2 on mast cells and also detected an intracellular pool of CXCR1/2. Here, we have addressed the question of receptor regulation during stimulation of human mast cells (HMC-1 cell line) and have studied T cells in comparison. Cell permeabilization was performed to detect both surface and possible intracellular receptor pools. HMC-1 cells stained positive for both receptors on the cell surface (CXCR1, 50%; CXCR2, 51%) and also after cell permeabilization (CXCR1, 86%; CXCR2, 74%). Similarly, T cells exhibited both cell-surface receptor expression (CXCR1, 30%; CXCR2, 23%) and higher total receptor expression (CXCR1, 50%; CXCR2, 36%), although overall values were lower than that in HMC-1 cells. On immunoblot, molecular weights of extra- and intracellular receptors on mast cells were the same, excluding altered receptor glycosylation. On stimulation with phorbol 12-myristate 13-acetate plus calcium ionophore, a time-dependent decrease of surface-membrane receptors was observed in both cell types, while total receptor remained the same, suggesting that receptor shedding is not involved. The kinetics of membrane receptor internalization and replenishment differed for the two cell types. Furthermore, receptor internalization was associated with decreased F-actin polymerization, a basic prerequisite for cell migration. These findings demonstrate for the first time the expression of extra- and intracellular CXCR1/2 receptors on T cells and delineate the dynamics of CXCR1/2 receptors on mast cells and T cells. Furthermore, they suggest a cell-type-specific and finely tuned regulation of chemokine responses at the receptor level in the context of inflammation
Ln1-xAxCoO3 (Ln = Er, La; A = Ca, Sr)/carbon nanotube composite materials applied for rechargeable Zn/Air batteries
Ln1-xAxCoO3 (Ln = Er, La; A = Ca, Sr)/Carbon Nanotube composite materials applied for rechargeable Zn/Air batteries / A. Weidenkaff, S. G. Ebbinghaus, T. Lippert. - In: Chemistry of materials. 14. 2002. S. 1797-180
Towards the chiral limit with dynamical blocked Wilson fermions
Barbour I, Laermann E, Lippert T, Schilling K. Towards the chiral limit with dynamical blocked Wilson fermions. Physical Review D. 1992;46(8):3618-3629.The approach to the chiral limit in full QCD is investigated with a blocked Wilson fermionic action. Finite size effects prohibit taking the chiral limit on small lattices. We find that various observables expected to be influenced by chiral and finite temperature properties of the theory reveal patterns which suggest a transition to chiral-symmetry restoration and deconfinement to be the origin of the observed phenomena
Comparison of a Planar Thin-Film Thermal AC Voltage Standard up to 1 MHz
This paper presents results of a trilateral comparison with a traveling ac voltage standard comprising a planar thin-film thermal converter. The ac–dc voltage transfer difference of the standard was measured at 1 V and at selected frequencies from 20 Hz to 1 MHz against primary thermal ac voltage standards at the Silesian University of Technology, Istituto Nazionale di Ricerca Metrologica, and Trescal
Advancing stem cells: New therapeutic strategies for treating central nervous system disorders
In this special issue, we explore new methods and knowledge to improve stem cell transplantation in diseases and conditions such as stroke, PD, and depression. Advancing the conventional idea regarding cell replacement in stem cell therapy, stem cells may also transfer healthy mitochondria to diseased ischemic neurons in stroke and improve the therapeutic time window of tissue plasminogen activator (tPA) in a conjunctive therapy for stroke, and human Wharton’s
Jelly-derived mesenchymal stromal cells (hWJ-MSCs) may rely mainly on trophic factor secretion to induce neuroprotective effects. In addition, trophic factors such as neurotrophin-4/5 (NT-4/5) and glial cell line-derived neurotrophic factor (GDNF) may enhance stem cell survival and differentiation to dopaminergic neurons for PD treatment, while encapsulating mesenchymal stem cells and GDNF-secreting cells may increase graft survival rates and their ability to promote neurogenesis and neurotrophic factor secretion in therapies for depression and PD. Of note, transfecting stem cells with a contrast agent such as a superparamagnetic iron oxide (SPIO) for tracking with magnetic resonance imaging (MRI) after transplantation may render these transplanted cells more vulnerable to toxicity in ischemic and hypoxic conditions. Moreover, other methods such as transient microglia depletion may protect against cosmic radiation-induced cognitive
impairments, and focusing on the collaborative efforts between oligodendrocytes and the neurovascular unit cells to repair damaged white matter may improve therapies for white matter injury
FFT for the APE Parallel Computer
We present a parallel FFT algorithm for SIMD systems following the "Transpose Algorithm" approach. The method is based on the assignment of the data field onto a one-dimensional ring of systolic cells. The systolic array can be universally mapped onto any parallel system. In particular for systems with next-neighbor connectivity our method has the potential to improve the efficiency of matrix transposition by use of hyper-systolic communication. We have realized a scalable parallel FFT on the APE100/Quadrics massively parallel computer, where our implementation is part of a two-dimensional hydrodynamics code for turbulence studies
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