267 research outputs found
Copium clavicorne subsp. reyi W AGNER 1954
No full textCopium clavicorne reyi W AGNER, 1954 F R A F r a n k r e i c h: Midi-Pyrenees, Albi, 7 Ex., 16. VI. 1954, leg. Weber.Published as part of Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1) on page 98, DOI: 10.5281/zenodo.750719
Antimicrobial Peptides, Infections and the Skin Barrier
No full textThe skin serves as a strong barrier protecting us from invading pathogens and harmful organisms. An important part of this barrier comes from antimicrobial peptides (AMPs), which are small peptides expressed abundantly in the skin. AMPs are produced in the deeper layers of the epidermis and transported to the stratum corneum, where they play a vital role in the first line of defense against potential pathogens. Numerous AMPs exist, and they have a broad antibiotic-like activity against bacteria, fungi and viruses. They also act as multifunctional effector molecules, linking innate and adaptive immune responses. AMPs play an essential part in maintaining an optimal and functional skin barrier - not only by direct killing of pathogens, but also by balancing immune responses and interfering in wound healing, cell differentiation, reepithelialization and their synergistic interplay with the skin microflora.</p
Precision measurement of the rovibrational energy-level structure of 4He+2
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Previous issue date: 6He is a three-electron system for which highly accurate textit{ab initio} calculations are possible._x000d_
The latest calculations of the rovibrational energies of He by Tung emph{et al.} footnote{W.-C. Tung, M. Pavanello and L. Adamowicz, textit{J. Chem. Phys.}, 136, 104309, 2012.} have a reported accuracy of 120 MHz, although they do not include relativistic and quantum electrodynamics (QED) effects. _x000d_
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We determined the rovibrational structure of He from measurements of the Rydberg spectrum of metastable He (He hereafter) and Rydberg-series extrapolation using multichannel quantum-defect-theory footnote{C. Jungen, textit{Elements of Quantum Defect Theory, in : Handbook of High-resolution Spectroscopy}, 2001.} footnote{D. Sprecher, J. Liu, T. Krähenmann, M. Schäfer, and F. Merkt, textit{J. Chem. Phys.}, 140, 064304, 2014.}._x000d_
He molecules are produced in supersonic beams with velocities tunable down to about 100 m/s by combining a cryogenic supersonic-beam source with a multistage Zeeman decelerator footnote{A. W. Wiederkehr, S. D. Hogan, M. Andrist, H. Schmutz, B. Lambillotte, J. A. Agner, and F. Merkt., J. Chem. Phys., 135, 214202, 2011.} footnote{M. Motsch, P. Jansen, J. A. Agner, H. Schmutz, and F. Merkt, textit{Phys. Rev. A}, 89, 043420, 2014.}. They are then excited to high-p Rydberg states by single-photon excitation._x000d_
In the experiments, we use a pulsed uv laser system, with a near Fourier-transform-limited bandwidth of 150 MHz. The Zeeman deceleration reduces the systematic uncertainty arising from a possible Doppler shift and greatly simplifies the spectral assignment because of its spin-rotational state selectivity footnote{P. Jansen, L. Semeria, L. E. Hofer, S. Scheidegger, J. A. Agner, H. Schmutz, and F. Merkt. Phys. Rev. Lett., 115, 133202, 2015.}._x000d_
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Results will be presented on the rotational structure of the lowest three vibrational levels of He. The unprecedented accuracy that we have obtained for the v rotational intervals of He footnote{L. Semeria, P. Jansen and F. Merkt, J. Chem. Phys., 145, 204301, 2016.} enables the quantification of the relativistic and QED corrections by comparison with the results of Tung emph{et al.}$^a
FINE STRUCTURE OF METASTABLE 4He2 USING ZEEMAN-DECELERATED MOLECULAR-BEAM RESONANCE SPECTROSCOPY
No full textThe state of He is a metastable state with a lifetime of about \,s.
The spin-spin and spin-rotation interactions result in a splitting of each rotational level into three components . The fine structure intervals of the , , , and - have been measured by radio frequency (rf) spectroscopy\footnote{W. Lichten, M.V. McCusker and T. L. Vierima, \textit{J. Chem. Phys.}, \textbf{61}, 2200 (1974).} \footnote{W. Lichten and T. Wik, \textit{J. Chem. Phys.}, \textbf{69}, 98 (1978).} \footnote{M. Kristensen and N. Bjerre, \textit{J. Chem. Phys.}, \textbf{93}, 983 (1990).} \footnote{I. Hazell, A. N\o rregaard and N. Bjerre, \textit{J. Mol. Spectrosc.}, \textbf{172}, 135 (1995).} and were included in a global analysis of the state \footnote{C. Focsa, P. F. Bernath and R. Colin, \textit{J. Mol. Spectrosc.}, \textbf{191}, 209, (1998).}.
A new measurement of the fine structure of all rotational levels between and of the () state will be presented. The fine-structure components, which are high-field seeking in magnetic fields, have been eliminated using a multistage Zeeman decelerator, and repopulated from the low-field-seeking components using rf radiation prior to detection by excitation to Rydberg states followed by pulsed-field ionization. The low velocity of the Zeeman decelerated beam\footnote{M. Motsch, P. Jansen, J. A. Agner, H. Schmutz and F. Merkt, Phys. Rev. A, \textbf{89}, 043420 (2014).} \footnote{P. Jansen, L. Semeria, L. E. Hofer, S. Scheidegger, J. A. Agner, H. Schmutz and F. Merkt, \textit{Phys. Rev. Lett.}, \textbf{115}, 133202 (2015).} enabled long interaction times of the molecules with the rf radiation and therefore a reduction of the transit-time broadening down to 10 kHz (FWHM), allowing the transition frequencies to be determined very accurately. The fine structure has been analyzed using an effective Hamiltonian to obtain improved values of the spin-spin and spin-rotation coupling constants for the () metastable state of He, including centrifugal distortion corrections
Copium teucrii subsp. iranum W AGNER 1969
No full text<i>Copium teucrii iranum</i> W AGNER, 1969 <p>I R N I r a n: Fars, Shiraz, 3 Ex., 13. V. 1969, leg. Eckerlein H. (3 Paratypes).</p> <p> <b> <i>Copium teucrii teucrii</i> (HOST</b> , <b>1788)</b></p> <p>A U T Ö s t e r r e i c h: Burgenland, Winden E / NSG Hackelsberg, 1 Ex., 24. V. 1967, leg. HA; Burgenland, Oslip SE / Silberberg, 1 Ex., 18. V. 2013, leg. LM; Niederösterreich, Hundsheimer Berg, 7 Ex., 22. VIII. 1960, leg. Weber; Nordtirol, Reutte, 1 Ex., 5. XI. 1914, leg. Knabl; Nordtirol, Zirl Umgebung, 49 Ex., 28. III. 1970, leg. HE; Nordtirol, Innsbruck NW: Planötzen, 1 Ex., 14. X. 1962, leg. HA; Nordtirol, Landeck, 1 Ex., fA, leg. Moosbrugger; Nordtirol, Zirl Umgebung, 14 Ex., 10. V. 1964, leg. HE; Nordtirol, Zirl, 1 Ex., 19. VII. 1962, leg. HA; Nordtirol, Zirl Umgebung, 3 Ex., 23. VI. 1962, leg. PE; Nordtirol, Zirl, 1 Ex., 24. V. 1957, leg. Burmann; Nordtirol, Fliess / Sonnenhänge, 1 Ex., 1. VIII. 1973, leg. HA; Nordtirol, Zirl Umgebung, 2 Ex., 23. V. 1964, leg. HE; Nordtirol, Zams NE / Steinseehüttenweg, 19 Ex., 10. IX. 1987, leg. KM; Nordtirol, Zirl Umgebung, 5 Ex., 12. VIII. 1962, leg. Kapeller R.; Nordtirol, Weissenbach / Feldele, 3 Ex., 22. IX. 1989, leg. KM; Nordtirol, Zirler Weinberg / Zirl NW, 14 Ex., 12. VIII. 1962, leg. HA; Nordtirol, Vomperbach / Schwaz SW, 1 Ex., 1. V. 1964, leg. HE; Nordtirol, Zirler Weinberg / Zirl NW, 5 Ex., 18. VIII. 1962, leg. HA; Nordtirol, Zirler Weinberg / Zirl NW, 2 Ex., 16. VIII. 1962, leg. HA; Nordtirol, Zirler Weinberg / Zirl NW, 2 Ex., 19. VII. 1962, leg. HA; Osttirol, Goggsteig / Lienz S, 2 Ex., 8. VI. 1963, leg. KA.</p> <p>B G R B u l g a r i e n: Warna, Varna (Warna), 3 Ex., 7. VIII. 1957, leg. Eckerlein H.</p> <p>F R A F r a n k r e i c h: Midi-Pyrenees, Albi, 29 Ex., 13. VIII. 1956, leg. Weber; Provence-AlpesCote d'Azur, Mont Ventoux, 1 Ex., 17. VI. 2013, leg. LM; Provence-Alpes-Cote d'Azur, Authon, 2 Ex., 10. VIII. 1956, leg. Eckerlein H.; Provence-Alpes-Cote d'Azur, Tarascon, 1 Ex., 4. VIII. 1955, leg. Eckerlein H.; Provence-Alpes-Côte d'Azur, Digne / Champ de Bes, 1 Ex., 22. VII. 1955, leg. Eckerlein H.</p> <p>G R C G r i e c h e n l a n d: Kreta, Malia, 1 Ex., fA, leg. Franz H.</p> <p>H U N U n g a r n: Wesprim,Vezprem/Liter, 1Ex., 22.V. 2014, leg. MH.</p> <p>I T A I t a l i e n: Brescia, Gargnano, 2 Ex., 1. VIII. 1972, leg. HE.</p> <p>J O R J o r d a n i e n: Amman Governorate, Amman, 1 Ex., 3. VI. 1956, leg. Klapperich J.</p> <p>M A R M a r o k k o: Souss-Massa-Draa,TiznitNE/FlussMassa, 2Ex., 8. V. 1967, leg. Eckerlein H.</p>Published as part of <i>Heiss, Ernst, Eckelt, Andreas, Lederwasch, Manfred, Unterasinger, Romed & T, Familie, 2022, Die Heteropterensammlung Ernst Heiss im Tiroler Landesmuseum Ferdinandeum. Teil V: Tingoidea, Familie Tingidae LAPORTE, 1832, pp. 85-142 in Linzer biologische Beiträge 54 (1)</i> on pages 98-99, DOI: <a href="http://zenodo.org/record/7507194">10.5281/zenodo.7507194</a>
Value of photo assessment in late patch-test readings—A multicenter study from six European patch-test clinics
No full textBackground: It is recommended that patch-test readings include a day (D)7 reading. Substitution of the D7 reading with a photo may be a valid option. Objectives: To compare the sensitivity of digital photos at D7 to clinical readings, to assess the number of positive reactions appearing at D7 only (late reactions), and after D7 only (delayed reactions). Methods: Patients patch tested in six European clinics were instructed to forward photos of the patch test reactions to the respective clinics at D7 (before attending the clinic) and at D21. Only allergens in the baseline series or TRUE Test were included in the data analysis. Results: Two hundred ninety-three of 629 patients had a total of 599 positive reactions, with 6.3% occurring at D7 only. When substituting the D7 reading with a photo (90% submitted), 26.3% of late reactions were missed and nine false-positive reactions were found. Delayed reactions were detected in four patients at D21 (65.3% submitted). Conclusion: Our data show that if the D7 reading is not performed, 6.3% of positive reactions from the baseline series would be missed, and if substituting the D7 reading by digital photo, 26.3% late reactions would be missed. Delayed reactions seemed rare
A computerized image analysis framework for dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) with applications to breast cancer
No full textDynamic contrast enhanced magnetic resonance imaging (DCE-MRI) provides a wealth of information about the anatomy of the breast, particularly in the setting of breast cancer diagnosis. In addition to the images it provides regarding the architecture of
breast tissue, it also provides functional information about blood flow by means of the DCE study. The sensitivity of DCE-MRI has been reported at close to 100%, so the difficult tasks for the radiologist in reviewing breast DCE-MRI are: (1) discerning
between which lesions are benign and which are malignant; and (2) doing so for a patient study that involves hundreds of images and is 4-dimensional. Because of the great detail and volume of information DCE-MRI provides, computational methods for both extracting and analyzing information derived from the images are useful in distilling the entire patient study down to the most salient images and features for the
radiologist to examine. In this dissertation, computer-based methods developed for
analyzing the data acquired in a breast DCE-MRI patient study are described. In the first part, pre-processing methods used for aligning the images of the timedependent DCE study are explained. Because segmentation is important for describing the morphology of the lesion as well as the region of interest for any subsequent quantitative analysis of a lesion, as a second step to pre-processing, a spectral embedding based active contour (SEAC) method for segmentation of lesions is developed and tested. A
feature developed for extracting the spatiotemporal characteristics of breast lesions, termed textural kinetics, is then described, and its utility is demonstrated for distinguishing benign from malignant lesions as well as in identifying triple negative breast
lesions, a lesion type that is extremely aggressive and has no targeted therapies. Finally, these quantitative methods are summarized in a computer aided diagnosis framework that provides insight into the biologic nature of breast lesion subtypes as well as for
directing treatment and determining prognosis.Ph.D.Includes bibliographical referencesby Shannon Christine Agne
Prevalence of dermatitis including allergic contact dermatitis from medical devices used by children and adults with Type 1 diabetes mellitus: A systematic review and questionnaire study
No full textAbstract
Use of medical devices (MDs), that is, glucose sensors and insulin pumps, in patients with Type 1 diabetes mellitus (T1D) has proven an enormous advantage for disease control. Adverse skin reactions from these MDs may however hamper compliance. The objective of this study was to systematically review and analyse studies assessing the prevalence and incidence of dermatitis, including allergic contact dermatitis (ACD) related to MDs used in patients with T1D and to compare referral routes and the clinical investigation routines between
clinics being part of the European Environmental and Contact Dermatitis Research Group
(
EECDRG
). A systematic search of PubMed, EMBASE, CINAHL and Cochrane databases of full‐text studies reporting incidence and prevalence of dermatitis in persons with T1D using MDs was conducted until December 2021. The Newcastle–Ottawa Scale was used to assess study quality. The inventory performed at EECRDG clinics focused on referral routes, patient numbers and the diagnostic process. Among the 3145 screened abstracts, 39 studies fulfilled the inclusion criteria. Sixteen studies included data on children only, 14 studies were on adults and nine studies reported data on both children and adults. Participants were exposed to a broad range of devices. Skin reactions were rarely specified. It was found that both the diagnostic process and referral routes differ in different centres. Further data on the prevalence of skin reactions related to MDs in individuals with T1D is needed and particularly studies where the skin reactions are correctly diagnosed. A correct diagnosis is delayed or hampered by the fact that, at present, the actual substances within the MDs are not declared, are changed without notice and the commercially available test materials are not adequately updated. Within Europe, routines for referral should be made more standardized to improve the diagnostic procedure when investigating patients with possible ACD from MDs
Patch testing with a textile dye mix - a multicentre study
No full textBackground Disperse dyes are well-known contact sensitizers. However, they are not included in the majority of commercially available baseline patch test series. Objectives To investigate the outcome of patch testing with a textile dye mix (TDM) consisting of eight disperse dyes at dermatology clinics in various countries. Patients/materials/methods Two thousand nine hundred and seven consecutive dermatitis patients at 12 dermatology clinics representing nine countries were tested with a TDM at 6.6%, consisting of Disperse Blue 35, Disperse Yellow 3, Disperse Orange 1 and 3, and Disperse Red 1 and 17, all at 1.0%, and Disperse Blue 106 and Disperse Blue 124, each at 0.3%, provisionally included in the baseline series. Eighty-seven per cent of the patients allergic to the TDM were also tested with the eight separate dyes. Results Contact allergy to TDM was found in 108 patients (3.7%). The frequency of contact allergy varied from 2.1% to 6.9% in different centres. Simultaneous reactivity to p-phenylenediamine was found in 57 of the TDM-positive patients (53%). The most frequent dye allergen among the TDM-positive patients was Disperse Orange 3. The contact allergy could have explained or contributed to the dermatitis in approximately one-third of the patients for whom clinical relevance of the TDM contact allergy was recorded. Conclusions The TDM should be considered for inclusion in the European baseline series. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
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