8,706 research outputs found

    Reproducibility of Complex Functional Magnetic Resonance Imaging Effects

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    Töpper M, Sammer G, Bauer E. Reproducibility of Complex Functional Magnetic Resonance Imaging Effects. Journal of the American Geriatrics Society. 2016;64(9):e62-e62

    Dissociating Normal Aging from Alzheimer’s Disease: A View from Cognitive Neuroscience

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    Töpper M. Dissociating Normal Aging from Alzheimer’s Disease: A View from Cognitive Neuroscience. Journal of Alzheimer's Disease. 2017;57(2):331-352.Both normal aging and Alzheimer’s disease (AD) are associated with changes in cognition, grey and white matter volume, white matter integrity, neural activation, functional connectivity, and neurotransmission. Obviously, all of these changes are more pronounced in AD and proceed faster providing the basis for an AD diagnosis. Since these differences are quantitative, however, it was hypothesized that AD might simply reflect an accelerated aging process. The present article highlights the different neurocognitive changes associated with normal aging and AD and shows that, next to quantitative differences, there are multiple qualitative differences as well. These differences comprise different neurocognitive dissociations as different cognitive deficit profiles, different weights of grey and white matter atrophy, and different gradients of structural decline. These qualitative differences clearly indicate that AD cannot be simply described as accelerated aging process but on the contrary represents a solid entity

    Enseñanza de la escritura de Max Aub: comprensión y memoria

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    Este texto analiza a obra testimonial de Max Aub sobre su experiencia en los campos de concentración en Francia desde una perspectiva de discursos comparados. Para destacar las estrategias de la escritura del autor recuperables por otros proyectos discursivos que persigan la sensibilización y la denuncia a través del cruce entre la comunicación y la éticaThis text analyses the testimonial work of Max Aub about his experience in the French concentration camps in France from comparative discourses approach. It emphasizes the writing strategies used by the author useful for other awareness and denounce discourses through the dialogue among communication and ethic

    Max Brooks literary reading flier

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    2012 Bismarck State College Visiting Writers Series and ArtsQuest present: Max Brooks. April 25, 7:30 p.m.; Belle Mehus Auditorium. Max Brooks is the author of World War Z: An Oral History of the Zombie War and the graphic novel The Zombie Survival Guide: Recorded Attacks

    Methodological Influences on the Association Between Self-Rated and Objective Memory Functioning : Preliminary Results

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    Dehn L, Töpper M, Driessen M, Beblo T. Methodological Influences on the Association Between Self-Rated and Objective Memory Functioning : Preliminary Results. GeroPsych. 2017;30(4):177-178

    Max Frisch's novel: Stiller. A study

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    The attempt is made in the following study to present an interpretation of the novel "Stiller" by the Swiss author, Max Frisch, by tracing through the novel the dominant themes of the graven-image or 'Bildnis' and that of the problem of freedom with reference to the novel's main character. ThesisMaster of Arts (MA

    A Transfer Report on the Development of a Framework to Evaluate Search Interfaces for their Support of Different User Types and Search Tactics

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    As the understanding of search systems, user needs and seeking strategies is developing, the design of search user interfaces is evolving to support more complicated and exploratory forms of search. With the design of new search features that enable these richer modes of exploration, comes the need to better understand the support they provide. In this report a new evaluation framework is presented that analyses search features for how they a) contribute to an overall interface, b) allow users to carry out different search tactics, and c) support different types of users and their needs. The novel contributions of the framework improve on some of the limitations of typical user studies, and allow search systems to be systematically analysed in much more detail and in much less time. The presented evaluation framework is then validated in three ways. First the validity of the models used as the building blocks of the framework are investigated through related work. Second the method of integrating these building-block models is validated and strengthened by consensus of expert opinion. Third, the overall approach is validated by comparing its analyses to the results of previously carried out user studies. The validation process has shown both the value of the framework and identified areas of future work that should be addressed for the framework to be completed. This report concludes with the set of contributions that the framework makes, and why the remaining work will be challenging, but critical to the final design

    Do self-reports provide valid information about driving fitness in seniors?

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    Schulz P, Spannhorst S, Iffland B, Töpper M. Do self-reports provide valid information about driving fitness in seniors? INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(2):231-232

    DOES MOUNT VESUVIUS INDICATE AN OUTBREAK OF ALZHEIMER'S DISEASE?

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    Töpper M, Boedeker S, Bauer E, Westphal S, Driessen M, Beblo T. DOES MOUNT VESUVIUS INDICATE AN OUTBREAK OF ALZHEIMER'S DISEASE? Journal of the American Geriatrics Society. 2014;62(10):1989-1991

    Recovery of driving fitness after stroke: A matter of time?

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    Schulz P, Schaebitz W‐R, Driessen M, Beblo T, Töpper M. Recovery of driving fitness after stroke: A matter of time? Journal of the American Geriatrics Society. 2022;70(5):1578-1580
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