47 research outputs found
Effects of Soaking of Sorghum And Utilization in Ready Mix for Traditional Fermented Products.
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this pag
Survey on Heuristic Search Techniques to Solve Artificial Intelligence Problems
Get PDFArtificial intelligence (AI) is an area of computer science that highlights the creation of machines that are intelligent, also they work and react like humans. Since AI problems are complex and cannot be solved with direct techniques we resort to heuristic search techniques. Heuristic search technique is any approach to problem solving, learning, or discovery which uses a practical methodology which is not guaranteed to be optimal or perfect, but it is sufficient for the immediate goals. This paper surveys some of the heuristic techniques which is used for searching an optimal solution among multiprocessor environment, followed by and method which enhances the search by doing a search in bidirection and also a method for task scheduling in multiprocessor environment. The paper also discuses about how heuristic is used to solve binary quadratic program and also how it is used in 3G (3rd Generation) Universal Mobile Telecommunication System (UMTS) network.
DOI: 10.17762/ijritcc2321-8169.15058
Dielectrophoresis: A Review of Applications for Stem Cell Research
Get PDFDielectrophoresis can discriminate distinct cellular identities in heterogeneous populations, and monitor cell state changes associated with activation and clonal expansion, apoptosis, and necrosis, without the need for biochemical labels. Demonstrated capabilities include the enrichment of haematopoetic stem cells from bone marrow and peripheral blood, and adult stem cells from adipose tissue. Recent research suggests that this technique can predict the ultimate fate of neural stem cells after differentiation before the appearance of specific cell-surface proteins. This review summarises the properties of cells that contribute to their dielectrophoretic behaviour, and their relevance to stem cell research and translational applications.</p
Clinical features, predisposing factors and radiological study of cerebral venous sinus thrombosis: experience from a tertiary care center in Southern India
Get PDFBackground: Cerebral venous thrombosis (CVT) is a less common cause of stroke with a wide range of clinical presentations, predisposing factors, radiological features and outcomes. A high index of suspicion is absolutely essential to diagnose cerebral venous thrombosis. In this article, we have reviewed the clinical spectrum and radiological profile of patients with cerebral venous thrombosis and attempted to identify the specific predisposing factors for developing cerebral venous thrombosis particularly in this region of India.Methods: 116 patients hospitalized from January 2015 to March 2017 with a final diagnosis of Cerebral Venous Thrombosis which was confirmed by imaging (MRI/MRV or CT angiography) were included. Patients who were initially diagnosed as CVT but imaging were not suggestive of the same were excluded.Results: The mean age of the study population was 35.21 years, with most patients aged between 21-30 years. 18.1% of the study population were puerperal women, much lower than earlier series. 54.54% of the men had a significant history of alcohol consumption and 10.34% of the non-puerperal women revealed a history of consuming oral contraceptive pills. Among men, seizures were the most common presenting symptom followed by headache. Women presented with headache followed by vomiting. Superior sagittal sinus, transverse sinus, cortical veins and sigmoid sinus involvement were quite common in comparison to the other sinuses.Conclusions: Accurate and prompt diagnosis of CVT is crucial because timely and appropriate therapy can reverse the disease process and significantly reduce the risk of acute complications and long-term sequelae. In this article, we have reviewed the epidemiology, causative factors, clinical features and as well as radiological pattern of CVT from an Indian perspective. Over the last decade, a relatively high incidence of CVT in fairly young individuals warrants further evaluation towards genetic predisposition for pro-thrombotic states particularly in this region of India.</jats:p
Human IgG1 antibodies suppress angiogenesis in a target-independent manner.
No full textberrant angiogenesis is implicated in diseases affecting nearly 10% of the world's population. The most widely used anti-angiogenic drug is bevacizumab, a humanized IgG1 monoclonal antibody that targets human VEGFA. Although bevacizumab does not recognize mouse Vegfa, it inhibits angiogenesis in mice. Here we show bevacizumab suppressed angiogenesis in three mouse models not via Vegfa blockade but rather Fc-mediated signaling through FcγRI (CD64) and c-Cbl, impairing macrophage migration. Other approved humanized or human IgG1 antibodies without mouse targets (adalimumab, alemtuzumab, ofatumumab, omalizumab, palivizumab and tocilizumab), mouse IgG2a, and overexpression of human IgG1-Fc or mouse IgG2a-Fc, also inhibited angiogenesis in wild-type and FcγR humanized mice. This anti-angiogenic effect was abolished by Fcgr1 ablation or knockdown, Fc cleavage, IgG-Fc inhibition, disruption of Fc-FcγR interaction, or elimination of FcRγ-initated signaling. Furthermore, bevacizumab's Fc region potentiated its anti-angiogenic activity in humanized VEGFA mice. Finally, mice deficient in FcγRI exhibited increased developmental and pathological angiogenesis. These findings reveal an unexpected anti-angiogenic function for FcγRI and a potentially concerning off-target effect of hIgG1 therapies
PROPERTIES OF CONCRETE WITH RED MUD AS PARTIAL REPLACEMENT OF CEMENT WITH HYDRATED LIME AND SUPERPLASTICIZER
Get PDFIn this research an attempt has been made to produce different grades of concrete using huge industrial waste such as red mud as a partial replacement of cement with the hydrated lime. This project presents the results of investigation on production of concrete members using a combination of materials which predominantly includes red mud and lime. The present study is mainly focused on the compressive strength, split tensile strength, flexural strength and durability properties of concrete, which are the important parameters to be studied in concrete production of different proportion of raw materials for different grades of concrete. However, when used in combination with 30% red mud, cement and 5% lime the composites shows significant compressive strength of 27.3N/mm2 and 50.05 N/mm2 for M20 and M40 grade of concrete. Tensile strength of 2.60 N/mm2, 4.98 N/mm2 for M20 and M40 grade of concrete. Selected combinations of mixes were later used to produce beam of size 500 x 100 x 100mm.
These beams are tested for flexural strength of results 2.4 N/mm2 and 3.29 N/mm2 for M20 and M40 grade of concrete. From this study it is revealed that 30% replacement of red mud along with 5% hydrated lime is found to be optimum
Investigations on Flow Characteristics of Mortars Using Partial Replacement of Fine Aggregates with Processed Granulated Blast Furnace Slag
No full textAssessment on Performance of Steel Slag and Processed Granulated Blast Furnace Slag as an Alternative for Fine Aggregate—An Assertive Review
No full textANALYTICAL METHOD DEVELOPMENT AND STATISTICAL VALIDATION OF DAPAGLIFLOZIN IN TABLET DOSAGE FORM AND BULK DRUG
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