1,405 research outputs found

    U-Pn geochronology of deformed metagranites in central Sutherland, Scotland: evidence for widespread late Silurian metamorphism and ductile deformation of the Moine Supergroup during the Caledonian orogeny

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    Within the Caledonides of central Sutherland, Scotland, the Neoproterozoic metasedimentary rocks of the Moine Supergroup record NW-directed D2 ductile thrusting and nappe assembly, accompanied by widespread tight-to-isoclinal folding and amphibolite-facies metamorphism. A series of metagranite sheets which were emplaced and penetratively deformed during D2 have been dated using SHRIMP UâPb geochronology. Zircon ages of 424 8 Ma (Vagastie Bridge granite), 420 6 Ma (Klibreck granite) and 429 11 Ma (Strathnaver granite) are interpreted to date emplacement, and hence regional D2 deformation, during mid- to late Silurian time. Titanite ages of 413 3 Ma (Vagastie Bridge granite) and 416 3 Ma (Klibreck granite) are thought to date post-metamorphic cooling through a blocking temperature of c. 550â 500 8C. A mid- to late Silurian age for D2 deformation supports published models that have viewed the internal ductile thrusts of this part of the orogen as part of the same kinematically linked system of forelandpropagating thrusts as the marginal Moine Thrust Zone. The new data contrast with previous interpretations that have viewed the dominant structures and metamorphic assemblages within the Moine Supergroup as having formed during the early to mid-Ordovician Grampian arcâcontinent orogeny. The mid-to late Silurian D2 nappe stacking event in Sutherland is probably a result of the collision of Baltica with the Scottish segment of Laurentia

    Assignment of the gene encoding human galanin receptor (GALNR) to 18q23 by in situ hybridisation

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    J. Nicholl, B. Kofler, G.R. Sutherland, J. Shine, T.P. Iisma

    Fragile X Syndrome

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    Fragile sites on human chromosomes : Demonstration of their dependence on the type of tissue culture medium . Science , 197 , 265 - 6 . Sutherland , G . R . ( 1979a ) . Heritable fragile sites on human chromosomes I . Factors affecting ..

    Erratum: Allen, G.R., Erdmann, M.V. & Purtiwi, P.D. (2017): Author Purtiwi, P.D. is spelled Pertiwi, P.D.

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    Allen, G.R., Erdmann, M.V. & Purtiwi, P.D. (2017) Descriptions of four new species of damselfishes (Pomacentridae) in the Pomacentrus philippinus complex from the tropical western Pacific Ocean. Journal of the Ocean Science Foundation, 25, 47–76. corrected spelling of third author’s name to: Allen, G.R., Erdmann, M.V. & Pertiwi, P.D. (2017) Descriptions of four new species of damselfishes (Pomacentridae) in the Pomacentrus philippinus complex from the tropical western Pacific Ocean. Journal of the Ocean Science Foundation, 25, 47–76

    The philosophy poetry of G.R. Derzhavin: the contrast of life and death

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    This article is devoted to the eshatological philosophical concept of the G.R. Derzhavins’ poetry. The author describes the presentation of the theme of death and its artistic transformation in the works of the poet as the reception of the Orthodox tradition, a kind of the cultural memory

    The construction of Karen Karnak: The multi-author-function

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    This thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author

    Strategies for sequencing human chromosome 16

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    This project funded for four years (02.92 to 01.96) was a renewal of a project funded for 2.5 years (07.89 to 01.92). This report covers the period 07.89 to 07.94. The original project was entitled {open_quotes}Correlation of physical and genetic maps of Human Chromosome 16{close_quotes}. The aim over this period was to construct a cytogenetic-based physical map of chromosome 16, to enable integration of its physical and genetic maps. This was achieved by collaboration and isolation of new markers until each bin on the physical map contained a polymorphic marker on the linkage map. A further aim was to integrate all mapping data for this chromosome and to achieve contig closure over band q24

    Localization of a gene for autosomal dominant nocturnal frontal lobe epilepsy to 20q13.2

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    Copyright © 1995 Nature Publishing GroupThe epilepsies comprise a group of syndromes that are divided into generalized and partial (focal) types. Familial occurrence has long been recognized but progress in mapping epilepsy genes has been slow except for rare cases where the inheritance is easily determined from classical genetic studies. Linkage is established for three generalized syndromes: the EBN1 and EBN2 genes for benign familial neonatal convulsions (BFNC) map to chromosomes 20q and 8q (refs 2-5), the EPM1 gene for Unverricht-Lundborg disease maps to 21q (ref. 6) and the gene for the northern epilepsy syndrome maps to 8p (ref. 7). A claim for linkage of the EJM1 gene for the common generalized syndrome of juvenile myoclonic epilepsy to 6p is currently in dispute. Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) was recently described in five families. We now report the chromosomal assignment, to 20q13.2, for the gene for ADNFLE in one large Australian kindred with 27 affected individuals spanning six generations.H.A. Phillips, I.E. Scheffer, S.F. Berkovic, G.E. Hollway, G.R. Sutherland & J.C. Mulle

    Complex organisation of the 5'-end of the human glycine tRNA synthetase gene

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    Glycine tRNA synthetase (glyRS) catalyses the addition of the amino acid glycine to its cognate tRNA molecules. In the silk moth worm Bombyx mori, this gene is subject to complex transcriptional regulation because of the predominance of glycine in silk. In vertebrates, glycine is a major constituent of collagen but there have been no studies of glyRS regulation. In this study we have isolated and mapped a genomic clone containing the 5'-end of glyRS. Primer extension studies identified only one transcriptional start point (TSP) in three different cell lines. Expression of the transcript identified may be regulated translationally because it contains five potential initiation codons, three of which are in good context for initiation. The most 3' of the potential initiation codons has previously been predicted to be the initiating codon for cytoplasmic glyRS. Two of the upstream codons are in-frame with this codon, and both are predicted to extend the N-terminus of glyRS to include a mitochondrial targeting sequence. Sequencing of genomic DNA surrounding the TSP showed features common to the promoters of housekeeping genes, as well as a canonical TATA box at the unusual position of +9. Surprisingly, promoter activity in vitro was not specified by a 1.9 kb genomic fragment containing the TSP and TATA box, but by a contiguous 0.4 kb fragment immediately downstream. These studies suggest that the transcription of glyRS from a single start point requires downstream promoter elements.Mudge, S.J ; Williams, J.H ; Eyre, H.J ; Sutherland, G.R ; Cowan, P.J ; Power, D.

    Spectral properties of Andreev reflection from quantum turbulence in 3He-B: What do they tell about turbulent fluctuations?

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    One of the experimental techniques developed to measure quantum turbulence at low temperatures in 3He-B utilizes the Andreev reflection of thermal quasiparticle excitations from quantized vortices and vortex structures. We present the results of theoretical, numerical, and experimental study of Andreev scattering from quantum turbulence in 3He-B. We analyze the spectral properties of the Andreev reflection and compare these with the spectral properties of superfluid turbulence, and discuss the physical mechanisms responsible for the scaling of spectral densities. Finally, we discuss the relation between our findings and related observables in ordinary turbulence
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