2,051 research outputs found
A diary in the Dardanelles written on board the sponer "Corsair" while beating through the straits from Tenedos to Marmora By William Knight, Esq. Rear-Commodore of the Royal Harwich Yacht Club, author of "Words for the Windbound" oriental outlines" etc e
No full textPreface: by knight, WIlliamAppendix.Dedication: by knight, W. to the members of the Royal Harwich yach clubContent description: Detailed contentsIllustration: 1 (Maps ,)Pagination: PP14+11OP+2PPVolumes: 1Text Genre:Journal / LettersIllustration: 1 (χάρτες ,
Performing focus groups: Unsettling 'blueprints'
No full textThis paper will explore the use of focus groups from two theoretical perspectives: poststructuralism and critical realism. The authors will bring together their understandings of these frameworks in the context of performing the focus group as a research method. They seek in particular to unsettle the notion that there is a particular ‘blueprint’ for conducting this research, as is implied in the literature discussing focus group method. Rather, they aim to highlight the importance of thinking about this method in terms of the theoretical framework being applied, in other words, how the theoretical ideas inform the performance of the research
Systematic review: the impact of exercise on mesenteric blood flow and its implication for preoperative rehabilitation
No full textBackgroundExercise in the preoperative period, or prehabilitation, continues to evolve as an important tool in optimising patients awaiting major intra-abdominal surgery. It has been shown to reduce rates of post-operative morbidity and length of hospital stay. The mechanism by which this is achieved remains poorly understood. Adaptations in mesenteric flow in response to exercise may play a role in improving post-operative recovery by reducing rates of ileus and anastomotic leak.AimsTo systematically review the existing literature to clarify the impact of exercise on mesenteric arterial blood flow using Doppler ultrasound.MethodsPubMed, EMBASE and the Cochrane library were systematically searched to identify clinical trials using Doppler ultrasound to investigate the effect of exercise on flow through the superior mesenteric artery (SMA). Data were extracted including participant characteristics, frequency, intensity, timing and type of exercise and the effect on SMA flow. The quality of each study was assessed using the Downs and Black checklist.ResultsSixteen studies, comprising 305 participants in total, were included. Methodological quality was generally poor. Healthy volunteers were used in twelve studies. SMA flow was found to be reduced in response to exercise in twelve studies, increased in one and unchanged in two studies. Clinical heterogeneity precluded a meta-analysis.ConclusionThe weight of evidence suggests that superior mesenteric arterial flow is reduced immediately following exercise. Differences in frequency, intensity, timing and type of exercise make a consensus difficult. Further studies are warranted to provide a definitive understanding of the impact of exercise on mesenteric flow
Indonesian EFL Curricula: What content knowledge demands do they make of Australian teachers?
No full textThis paper reports on the experiences of four Australian teachers who provide English as a Foreign Language (EFL) instruction to Indonesian secondary school students in a regional area of Central Java, Indonesia. These four teachers were all native English speakers and experienced qualified teachers, however, the Australian State Department of Education that sent them to Indonesia did not provide them with formal EFL teaching qualifications or experience. This paper theorises the teachers’ talk about their teaching work in Indonesia in an attempt to identify the forms of content knowledge they required to do their teaching. Two significant findings emerged from this research. Firstly, the teachers encountered two distinctively different EFL curricula in Indonesia: the formal EFL Indonesian National Secondary School curriculum and an informal EFL curriculum that the teachers introduced. Each of these curricula required the teachers to draw upon a different content knowledge base. The second significant finding was that these unqualified and inexperienced EFL teachers were not able to make an effective contribution to the formal EFL Indonesian National Secondary School curriculum because they were not given an opportunity to acquire the requisite content knowledge base. Such findings should be of interest to teachers and program managers involved in EFL curricula
International year of older persons: Mentoring research project
No full textA report, by Judith MacCallum and Susan Beltman, Murdoch University, that identifies models of good practice of mentoring in school settings. The report looks at issues associated with the implementation of mentoring programs in school settings and key recommendations for consideration by Australian schools and education systems
Investing in early childhood : creating a community of care for children and families
No full textInvesting in early childhood care and education services contributes to the lifetime well-being of children and families. Early childhood teachers work at the frontline of this investment, supporting families and dealing with day-to-day issues that impact on the lives and learning of young children. These teachers work within prevailing social and political structures yet they are also co-constructors of service provisions as they are experienced by families with young children. Nine teachers with work experience in a range of early childhood services engaged in conversations about key issues and contextual challenges facing their work as early childhood professionals. Three challenges raised by these teachers are examined to draw attention to the reality that creating a community of care for children and families requires re-thinking the role of the early childhood professional in service provision. This paper contributes to knowing about what it means to teach in contemporary early childhood contexts and to understanding how and why teachers find it difficult but necessary to actively promote connectedness and a sense of community across local services for children
CARATTERIZZAZIONE IMMUNOISTOCHIMICA E MOLECOLARE DI DISORDINI LINFOPROLIFERATIVI IN PRIMATI XENOTRAPIANTATI CON PRECURSORI NEURONALI
No full textIntroduzione: I disordini linfoproliferativi post-trapianto (PTLD) rappresentano un gruppo di malattie che insorgono in corso d’immunosoppressione dopo il trapianto (Tx). La maggior parte dei PTLD nell’uomo e nel primate sono dovuti alla presenza di Epstein-Barr virus e Lymphocryptovirus (MacLCV).
Materiali e Metodi: 28 adulti di Macaca fascicularis con malattia di Parkinson farmacologicamente indotta hanno ricevuto precursori neuronali di suini transgenici per CTLA4Ig (n=7) e wild-type (n=2).. La caratterizzazione di PTLD ha riguardato aspetti morfologici, immunoistochimici (IHC) e molecolari.
Risultati: i PTLD sono stati diagnosticati in 9 animali, ad una distanza media di 172,7 giorni dal tx.. Le neoplasie erano localizzate nelle cavità nasali (n=3), nell’intestino (n=4) e in entrambe le sedi (n=2). Istologia e IHC hanno rivelato un PTLD monomorfo (linfoma a grandi cellule B) di grado elevato. IHC a doppia marcatura per EBNA2 e CD20 ha dimostrato un’elevata percentuale di cellule neoplastiche CD20+ e EBNA2+. RT-PCR e sequenziamento dei trascritti di EBNA-1, EBNA-2 e LMP-1 eseguiti su 5 primati PTLD+ hanno evidenziato che EBNA-1 e EBNA-2 sono sempre presenti, mentre l’espressione di LMP1 è assente. Il DNA di MacLCV è stato isolato in tutti i primati riceventi ela viremia è stata evidenziata circa 60 gg prima dei sintomi clinici.
Conclusioni: lo studio identifica un pattern di espressione dei trascritti virali nel PTLD associato a MacLCV: EBNA-1+ EBNA-2+ LMP-1-. Nel ricevente si evidenzia un picco viremico di MacLCV prima dell’insorgenza del PLTD. Tale test potrebbe essere utilizzato come strumento precoce per la diagnosi di PTLD
Supplemental Material - Non-pharmacological rehabilitation interventions for individuals with antiphospholipid syndrome: A scoping review
No full textSupplemental Material for Non-pharmacological rehabilitation interventions for individuals with antiphospholipid syndrome: A scoping review by Alexandra E Harper, Yen T Chen, Stephanie Tancer, Kyla R Rodgers, Amber D Crumb, Whitney A Townsend, Jason S Knight and Susan L Murphy in Lupus.</p
Challenging the Authority of Identity: The Spaces of Memory in Medieval English Romance.
No full textAs episodic narratives, romances depend upon an inherent understanding of the powers of memory and recollection to ensure that the authority of characters, narratives and the chivalric ideal are identified and sustained. Memory is mapped onto literal journeys, places, and correlative experiences, and the thesis examines the processes through which this is achieved in medieval English romances. Distractions of the present are often complicated by unfamiliarity, forgetfulness, disguises and incognito, or threats from Otherworldly challenges, (mis)fortune, and time itself. Consequently, in contrast to simple learning in the manner of mnemonics, romances promote a dynamic continuum between past and present which preserves the medieval memorial principles of order and place along with the creative freedom for interpretation advocated at the heart of medieval memoria. Using classical and medieval memory theories, the thesis examines the creative challenges for memory in a selection of established romances such as Sir Gawain and the Green Knight, Sir Orfeo, Emaré, and King Horn, including those of Chaucer and Malory, along with lesser studied, longer romances such as William of Palerne, Ipomadon and Beves of Hamtoun. Characters and audiences create their own stable set of memories from within and beyond each tale which they recollect, often as imaginatively changed forms, into present experiences and future situations. By avoiding the temptation to forget and remaining open to referential moments, a lost knight is united with his remembered love, situations mysteriously chime with those witnessed before, and pressures of change become the reassuring familiarity and expectation of a past reimagined. In romances the memorial places, objects, and rituals are of great importance, but so too are the spaces between these recognisable points. This is the expanse of time which allows the creative work of memory to truly flourish and preserves the identity and authority of the narratives themselves
Assessment of quality of life in children with peanut allergy
No full textChildren with a peanut allergy (PA) are faced with food and social restrictions due to the potentially life-threatening nature of their disease, for which there is no cure or treatment. This inevitably impacts upon their quality of life (QoL). QoL of 20 children with PA and 20 children with insulin-dependent diabetes mellitus (IDDM) was measured using two disease-specific QoL questionnaires (higher scores correspond to a poorer QoL). One questionnaire was designed by us and the other was adapted from the Vespid Allergy QoL questionnaire. We gave subjects cameras to record how their QoL is affected over a 24-h period. Response rates for both questionnaires were 100%. Mean ages were 9.0 and 10.4 years for PA and IDDM subjects, respectively. Children with a PA reported a poorer quality of life than children with IDDM: mean scores were 54.85 for PA subjects and 46.40 for diabetics (p = 0.004) in questionnaire 1 and 54.30 and 34.50 (p?0.001) in questionnaire 2. PA children reported more fear of an adverse event and more anxiety about eating, especially when eating away from home. Photographs fell into seven common categories: food, management, environment, away from home, physical activities, restaurant and people. Most photographs related to food and management issues and revealed difficulties for both groups regarding food restrictions. PA subjects felt more threatened by potential hazards within their environment, felt more restricted by their PA regarding physical activities, and worried more about being away from home. However, they felt safe when carrying epinephrine kits and were positive about eating at familiar restaurants. The QoL in children with PA is more impaired than in children with IDDM. Their anxiety may be considered useful in some situations, promoting better adherence to allergen avoidance advice and rescue plans
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