156 research outputs found
Replication Data for: Nasopharyngeal pneumococcal concentration among children in a longitudinal study of household respiratory virus transmission in Kilifi, Kenya
No full textThese data include pneumococcal concentration measured by quantitative PCR from nasopharyngeal swab samples collected from children during a longitudinal study of viral transmission among households in rural Kenya. The parent study has been described elsewhere, but in brief, swabs were collected twice weekly from all members of 47 households in Kilifi County, Kenya during the RSV season from December 2009 until June 2010. Swabs collected during periods of upper respiratory tract infection associated with viral (RSV or rhinovirus) infection from children <5 years old, swabs from the 2 weeks prior to such viral infection periods and swabs from the 4 weeks following such periods, were examined. A quantitative pneumococcal PCR (lytA) was adjusted for the concentration of human DNA present (as measured by a quantitative alu PCR) for each such swab.</p
Replication Data for: Nasopharyngeal pneumococcal concentration among children in a longitudinal study of household respiratory virus transmission in Kilifi, Kenya
No full textThese data include pneumococcal concentration measured by quantitative PCR from nasopharyngeal swab samples collected from children during a longitudinal study of viral transmission among households in rural Kenya. The parent study has been described elsewhere, but in brief, swabs were collected twice weekly from all members of 47 households in Kilifi County, Kenya during the RSV season from December 2009 until June 2010. Swabs collected during periods of upper respiratory tract infection associated with viral (RSV or rhinovirus) infection from children <5 years old, swabs from the 2 weeks prior to such viral infection periods and swabs from the 4 weeks following such periods, were examined. A quantitative pneumococcal PCR (lytA) was adjusted for the concentration of human DNA present (as measured by a quantitative alu PCR) for each such swab
Ti:sapphire fabrication via high energy ion implantation
No full textDeposited with permission of the author. © 2002 Leigh David Morpeth.A Ti:sapphire waveguide laser is attractive as it would provide a compact, stable, broadly tunable (660-1180 nm) and versatile radiation source ideal for remote sensing or spectroscopy. This thesis reports the applicability of ion implantation to the fabrication of the Ti:sapphire waveguide laser in c-axis oriented Al2O3. These results comprise the first realisation of the Ti:Al2O3 material by ion implantation. The substrate quality was optimised for the synthesis conditions and co-implantation was explored though a comparative study of Cr/O. The formation of waveguides via direct and indirect approaches was then pursued with limited success
The choral foundation of Durham Cathedral, c.1350 - c.1650
No full textThe muniments of Durham cathedral, city, and diocese have been explored in order to present and assess the contribution made by lay musicians to worship in the cathedral. By 1335-60 the boys and men had become sufficiently established to merit specific payments. Whether or not the lay Cantor dates back that far is uncertain, but in 1390 it was agreed that what was required was a Cantor-Instructor. No proof for the implementation of this earlier than 1415 has come to light, nor has any contract earlier than that made by the monastery with John steel in 1430. From it and those of his successors, and from Rites of Durham, a picture emerges of the Cantor's duties and of the part played by boys and men in the daily Lady Mass in the Galilee chapel and in the Mass of the Name of Jesus on Fridays in the nave. Following the suppression of its monastic arm in 1539 Durham was re-constituted a cathedral only in 1541 . The pattern of worship established c.1560 continued until the 1620s, when the innovations introduced by John Cosin caused Peter Smart (a Calvinist) to preach a vituperative sermon on 27 July 1628. From the litigation which ensued much emerges about whole ordering of worship in Durham since the 1560s. Produced whilst the ceremonialists held sway were several sets of new music books for the choir. Some 40% of these are still in Durham. such is the detail in the muniments that it has proved possible to suggest when the books were transcribed and by whom. It has also proved possible to identify the contributions of no fewer than eight Durham scribes to the music books at Peterhouse, Cambridge. That their work should be so far afield is explained by the fact that when John Cosin became Master of Peterhouse i n 1635 he re-established the post of College organist and drew heavily upon the Durham repertoire. The succession of Cantors and Masters of the Choristers provided the framework on which to interweave details of their lives, historical events and musical developments. Biographical information relating to the other members of the choir has been assembled in Appendix 1. This is followed other Appendices many of which present together all occurrences of certain fields of information
Breaking the conjugal vows : marriage and marriage breakdown in the north of England, 1660-1800.
No full textSIGLEAvailable from British Library Document Supply Centre-DSC:DXN029014 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
Replication Data for: Carriage and acquisition of Extended Spectrum Beta-Lactamase producing Enterobacterales among neonates admitted to hospital in Kilifi, Kenya
No full textInfections caused by extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) among hospitalized neonates in sub-Saharan Africa pose significant clinical challenges.
In a cohort study of consecutive neonatal admissions to Kilifi County Hospital (KCH) from July 2013-August 2014, we estimated ESBL-E carriage prevalence on admission using rectal swab cultures and identified risk factors using logistic regression. Swabs were collected at day 0, 2, 4 and 6 and twice-weekly follow up swabs thereafter, we estimated the incidence and identified risk factors for ESBL-E acquisition in hospital using Poisson regression.
Data includes admission data for study participants, specimens collected and laboratory results and subsequent data analysis. The prevalence of ESBL-E carriage at admission was 10% (59/569). Caesarean section delivery, older neonatal age, and smaller household size were significant risk factors. Of the 510 infants admitted without ESBL-E carriage, 238 (55%) acquired carriage during their hospital stay. The incidence of acquisition was 21.4% (95% CI 19.0, 24.0) per day. The rate was positively associated with the number of known neonatal ESBL-E carriers and with the total number of neonates on the same ward.</p
Author Correction: Bacteriological diagnosis of childhood TB: a prospective observational study.
No full textA correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper
Making standards for quantitative real-time pneumococcal PCR.
No full textQuantitative lytA PCR is often performed using in-house standards. We hypothesised equivalence when measuring a standard suspension of Streptococcus pneumoniae by colony-forming-units (CFU) or genome-copies. Median (IQR) ratio of CFU/genome-copies was 0.19 (0.1-1.2). Genome-copies were less variable than CFU, but the discrepancy between the methods highlights challenges with absolute quantification
The Liber Vitae of Durham (BL MS Cotton Domitian A. vii): a discussion of its possible context and use in the later middle ages
No full textThis thesis examines in detail the history and use of the Liber Vitae of Durham (BL MS Cotton Domitian A. vii). The manuscript is one of a small group of similar manuscripts created by different monasteries to record the names of associates of the monastery to be remembered during the round of monastic prayer. The Liber Vitae was first created in the mid-ninth century in Northumbria. Between c.1083 and c.1539 the monks of Durham used it to record the names of members of the monastic community together with large numbers of non-monastic names. In the first section of the thesis the history and development of the manuscript is explored through a detailed consideration of its codicology, supported by a discussion of the development of the lists of names over five hundred years. The phases of the development of the manuscript discovered by these means are then placed in their historical context, first in ninth century Northumbria and then in Durham between the eleventh and sixteenth centuries. In the second section the evidence for the way in which the book might have been used in the liturgy is examined. The possible uses of the book are particularly compared with the other evidence available from Durham for the ways in which friends and benefactors of the monastery were commemorated. In the final section the non-monastic names written into the manuscript after c. 1300 are examined in detail to try to define what group of associates of the priory of Durham are in fact commemorated in the Liber Vitae
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