466 research outputs found

    Liam Rector, 14th Annual ODU Literary Festival

    No full text
    Liam Rector is the author of The Sorrow of Architecture, a book of poems. He\u27s also the editor of The Day I Was Older: On the Poetry of Donald Hall. He has taught at Old Dominion University, George Mason, Goucher College, and Phillips Academy at Andover. In addition, he has administered literary programs at the Folger Academy of American Poets. Currently, Liam Rector is executive director of Associated Writing Programs, which has lately taken a leading role in defending the 1st amendment. Rector has been awarded both NEA and Guggenheim fellowships for poetry

    Liam Rector, 12th Annual ODU Literary Festival

    No full text
    Liam Rector is the author of a book of poetry, The Sorrow of Architecture, 1984, and editor of The Day I Was Older: On the Poetry of Donald Hall, 1989, and is currently working on a second book of poems, tentatively titled The Persistence of Virginia. He is executive director of the Associated Writing Programs, located at Old Dominion University

    Project Triton : A study into delivering targeted information to an individual based on implicit and explicit data.

    No full text
    The World Wide Web is frequently seen as a source of knowledge, however much of this remains undiscovered by its users. In recent times, recommender systems (e.g. Digg and Last.fm) have attempted to bridge this gap, alerting users to previously untapped knowledge. As more socially oriented services appear on the Web (e.g. Facebook and MySpace), it has never been easier to obtain information pertaining to an individual’s interests. At present, solutions for automated data recommendation tend to be highly topic specific (recommending only a certain topic such as news) and often only allow access to the system using monolithic interfaces. This report hopes to detail the stages from research to evaluation involved in creating an extensible framework, which will operate without the need for human intervention. The framework will feature several proof-of-concept plugins residing in a custom workflow, which target information that is useful to the user. Information will be retrieved automatically through plugins involved with data gathering (such as feed processing and page scraping), while users’ interests will be obtained implicitly (for example, using header information to derive location) or explicitly (taking advantage of Social Network APIs such as Facebook Connect). Finally, Third Parties will be able to integrate the framework into their own solutions using the customisable XML API (written in PHP), so that their products can provide custom user interfaces without style constraints

    Design, fabrication and molecular modeling of protein subunits for use in a novel hydrogel:

    No full text
    Use of bioinspired, genetically engineered proteins in tissue engineering scaffolds represents a new opportunity for engineering these constructs. However, the production and rational modification of new, artificial proteins is hindered by significant gaps in knowledge regarding expression of artificial gene constructs in E. coli and their molecular modeling. This thesis focuses on the production of a novel hydrogel scaffold composed of four self-assembling protein modules and their rational modification using Molecular Dynamics (MD) simulations. Two of the modules are based on the ABA triblock copolymer design. In this triblock, a hydrophilic, random coiled region is flanked by 28 amino-acid α−helical endblocks. The purpose of these endblocks is to function as virtual crosslinkers and support network formation. The length of the endblocks can be changed by the addition of two unlinked, fiber-forming peptides and thus potentially alter the gelation and melting points of the hydrogel. We evaluate the efficacy of production of these endblocks by two separate expression strategies in E. coli and demonstrate their ability to form hydrogels. Furthermore, we analyze the Gibbs free energy of formation of oligomeric intermediates that arise early on during fibrillogenesis from the unlinked peptides using the MM/PBSA module of Amber 9. Thermodynamic data demonstrates changes in the primary structure of these peptides affect the stability of the intermediate that seeds fiber formation. This analysis also suggests a shift in the fiber forming mechanism from monomer addition to protofibril addition. We offer how this data can be used to improve interhelical interactions between endblocks and unlinked peptides and how to develop coarse-grain models of fiber formation.Ph.D.Includes bibliographical referencesby Christopher Liam Gaugha

    Trips-plus Provisions in European Union Agreements: Enhanced Protection of Intellectual Property or Restriction of Human Rights?

    Full text link
    This thesis charts, and investigates the role of Trade-Related Aspects of Intellectual Property Rights (TRIPS)-Plus provisions to protect intellectual property rights in the European Union (EU) international agreements. It critically discusses the extent to which the EU is seeking higher levels of intellectual property (IP) protection in the global sphere and analyses whether and to what extent the use of TRIPS-Plus provisions potentially clashes with the objective of the promotion and protection of human rights in the EU external action. This analysis is conducted across two intertwined axis: a chronological one and a conceptual one, in order to understand the evolution of the balance between IP and human rights protection. The main and overarching research question to which this thesis aims to answer is the following: To what extent and how has the EU reconciled high levels of IP protection with the promotion of human rights in its own international agreements? In answering this question, this thesis also purports broader considerations on the overall coherence of EU international agreements with the objectives laid down in Articles 3 and 21 of the Treaty on the European Union (TEU). The theoretical framework of this research is that of the EU’s ‘constitutional regime governing foreign affairs’, and, in line with it, the approach adopted is normative, and the methodology used is doctrinal. This PhD dissertation is divided into three parts. The first part discusses the evolution of IP protection at the international level. The second part examines the position of IP rights within the EU, the competence of the EU to act in the IP field both internally and externally. The third and final part of this thesis systematically examines IP provisions in EU agreements and discusses the extent to which IP protection might conflict with the promotion of human right

    The Marrakesh VIP Treaty, Accessibility, and (E)U

    No full text
    In an effort to combat the global ‘book famine’ for individuals with visual impairments, in that over 90% of the printed works of the work were unavailable to them in an accessible format, the international community developed and ratified the Marrakesh Treaty to Facilitate Access to Published Works by Visually Impaired Persons and Persons with Print Disabilities (Marrakesh VIP Treaty). The Treaty's purpose was to provide new and improved methods of accessibility while not infringing the protections afforded by copyright on the printed works. As digitalisation and improvements to text to speech narration advanced in line with other technologies, arguably, it became easier and more cost-effective to adapt the material for those with visual impairments. However, in doing so, the adaptation ran afoul of copyright protection. The Marrakesh VIP Treaty thus facilitates this adaption while not infringing or preventing future commercial exploration of the work in question.This paper seeks to outline the context for the introduction, negotiation, and ratification of the Marrakesh VIP Treaty within the broader spirit of the CRPRD from the perspective of the European Union (EU). It also analyses the EU’s ability to include human rights-related goals as part of its external relations policy and the question of competence to act in this regard in relation to the Marrakesh VIP Treaty. Finally, it examines each trade-based agreement following the ratification of the Marrakesh VIP Treaty by the EU to assess whether they are aligned to the spirit of the Treaty. In doing so, the innovative and protective aspects are contrasted with requirements to protect and promote various human rights, such as the rights of the person with disabilities and where the Marrakesh VIP Treaty shapes the rights to education, knowledge, culture, and the impact such inclusion has in addressing the global ‘book famine’
    corecore