40 research outputs found

    Endoscopic diagnosis, management and outcome of gastroduodenal tuberculosis

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    Current guidelines for gastroduodenal tuberculosis suggest that surgery in conjunction with anti-tubercular therapy (ATT) is the primary therapy. We determined the efficacy of endoscopic balloon dilatation along with ATT as the primary treatment for this condition. Patients with gastric outlet obstruction at endoscopy seen over a two-year period underwent multiple biopsies from the involved area. Those in whom mucosal biopsy revealed non-specific inflammation, underwent endoscopic mucosal resection (EMR). Patients showing granulomatous inflammation with/without acid-fast bacilli (AFB) underwent endoscopic balloon dilatation under fluoroscopic guidance along with ATT. End point of dilatation was taken as dilatation with 18 mm balloon. The time taken to resume normal diet post endotherapy was determined. Thirteen patients were diagnosed to have gastroduodenal tuberculosis. Granulomatous inflammation with or without demonstration of AFB was documented in 92 % of the patients by endoscopic biopsy and EMR. Endoscopic balloon dilatation of the strictures was successful in 11/12 patients (92 %); these patients could resume their normal diet at a median of 11 days (range 7-60) post-dilatation. Retroperitoneal perforation in 1 patient was managed conservatively. Endoscopic therapy in combination with ATT is recommended as the first line therapy for gastroduodenal tuberculosis. Surgical intervention is reserved for the minority in whom endoscopic therapy fails.Amarender Singh Puri, Sanjeev Sachdeva, Vibhu Vibhas Mittal, Nitin Gupta, Ameet Banka, Puja Sakhuja, Sunil Kumar Pur

    Plane Strain Deformation In Thermoelastic Microelongated Solid

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    The purpose of this paper is to study the two dimensional deformation in a thermoelastic microelongated solid. A mechanical force is applied along the interface of fluid half space and thermoelastic microelongated half space. The normal mode analysis has been applied to obtain the exact expressions for displacement component, force stress and temperature distribution. The effect of microelongation on the displacement component, force stress and temperature distribution has been depicted graphically for Green-Lindsay (GL) theory of thermoelasticity. Keywords: Thermoelasticity, Microelongation, Normal mode analysis

    A two dimensional fibre reinforced micropolar thermoelastic problem for a half-space subjected to mechanical force

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    The purpose of this paper is to study the two dimensional deformation of fibre reinforced micropolar thermoelastic medium in the context of Green-Lindsay theory of thermoelasticity. A mechanical force is applied along the interface of fluid half space and fibre reinforced micropolar thermoelastic half space. The normal mode analysis has been applied to obtain the exact expressions for displacement component, force stress, temperature distribution and tangential couple stress. The effect of anisotropy and micropolarity on the displacement component, force stress, temperature distribution and tangential couple stress has been depicted graphically

    Coronavirus Disease 2019 (COVID-19): a new challenge in untreated wastewater

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    COVID-19 outbreak was declared a pandemic by the WHO on 12 March 2020. As of 27 May 2020, WHO statistics exhibited that more than five million confirmed cases have been reported globally. Much remains unclear about the fate and impact of SARS-CoV-2, the novel coronavirus 2019, in wastewater. SARS-CoV-2 infection, the etiologic agent of the current COVID-19 pandemic, is followed by virus shedding in the stool. The quantification of SARS-CoV-2 in wastewater, therefore, enables monitoring of the prevalence of infections among the population through wastewater-based epidemiology. This review discusses the possible spread of the SARS-CoV-2 virus in wastewater and its impact on human health, if any. The information and resources outlined in this paper are based on recently published studies and provide information to decision-makers on the successful management of COVID-19 and reduce the risk of human exposure to COVID-19. Additionally, systems-based approaches to curtail COVID-19 spread are also discussed.The presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author

    A two dimensional problem on laser pulse heating in thermoelastic microelongated solid

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    In the present discussion, the plane strain deformation due to laser pulse heating in a thermoelastic microelongated solid has been discussed. The analytic expressions for displacement component, force stress, temperature distribution and micro-elongation have been derived. The effect of pulse rise time and micro-elongation on the derived components have been depicted graphically
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