24,254 research outputs found
Helina septentrionalis Xue and Cui 2003
No full textHelina septentrionalis Xue and Cui, 2003 Distribution Heilongjiang (type-locality: Wuying)Published as part of Xue, Wanqi & Sun, Hongkui, 2014, Diagnosis and key for the Helina annosa-group (Diptera: Muscidae) from China, with descriptions of nine new species, pp. 1549-1583 in Journal of Natural History 49 (25) on page 1570, DOI: 10.1080/00222933.2014.954019, http://zenodo.org/record/400627
Psychometric network analysis of the Intuitive Eating Scale-2 in Chinese general adults
No full textThe Intuitive Eating Scale-2 (IES-2) is a measure of intuitive eating behaviors that has been extensively validated, with traditional latent variable modeling approaches, in youth and adults from many different populations, including college students in China. However, there is still a lack of research on the psychometric properties of the IES-2 in adults from the Chinese general population. Moreover, psychometric network analysis, as a complement to traditional latent variable modeling approaches, has not been used for examining the psychometric properties of the IES-2. Thus, the present study used a psychometric network approach to evaluate the psychometric properties of the IES-2 in Chinese adults from the general population. A sample of 700 Chinese general adults (50% women; Mage = 31.13 years, SD = 9.19) recruited online were included in the present study. Psychometric network analysis was performed. Exploratory graph analysis (EGA) identified four dimensions, which were well separated in the estimated network. The network structure showed excellent stability and metric measurement invariance (i.e., network loadings) across men and women. Furthermore, several items on the IES-2 were identified as key nodes in the network of the IES-2 that may be important for the development and maintenance of intuitive eating. For example, two items (i.e., “I trust my body to tell me when to eat,” and “I trust my body to tell me when to stop eating”) related to reliance on body cues were the most impactful nodes in the complete network. The findings of our study provide a greater understanding of the IES-2 from the perspective of network analysis and have implications for applications of intuitive eating interventions for general populations.</p
Two new meroterpenes with activity against diacylglycerol acyltransferase from seeds of Psoralea corylifolia
No full textTwo new meroterpenes, 7β, 13β-Psoracorylifol B (1) and 7β, 8α-Psoracorylifol D (3) together with eight known compounds (2, 4 - 10) were isolated from the seeds of Psoralea corylifolia L. They were identified by a series of spectroscopic methods to determine their structures and all the compounds were evaluated for in vitro inhibitory activity against DGAT1/2. Among them, compounds 1-5 and 10 showed moderate inhibitory activity against DGAT1 with IC50 values ranging from 67.1 ± 1.3？130.4 ± 1.2 μM, compounds 1-2 showed weak inhibitory activity against DGAT2 with IC50 values 132.9 ± 1.1 and 134.2 ± 1.2 μM.
Native p-type transparent conductive CuI via intrinsic defects
No full textThe ability of CuI to be doped p-type via the introduction of native defects has been investigated using first-principles pseudopotential calculations based on density functional theory. The Cu vacancy has a lower formation energy than any of the other native defects, which include I vacancy (V(I)), Cu interstitial (Cu(i)), I interstitial (I(i)), Cu antisite (Cu(I)), and I antisite (I(Cu)). Combined with its shallow acceptor level, it offers sufficient hole concentrations in CuI. The natural band alignments as compared to zinc-blende ZnS, ZnSe, and ZnTe have also been calculated in order to further identify the p-type dopability of CuI. It is found that CuI has a relatively high valence band maximum and conduction band minimum, which also makes it easy to dope CuI p-type in terms of the doping limit rule. In addition, the small effective mass of the light hole-about 0.303m(0)-can provide high mobility and p-type conductivity in CuI. All of these results make CuI an ideal candidate for native p-type materials (C) 2011 American Institute of Physics. [doi:10.1063/1.3633220
System-Level Vulnerability Assessment for EME: From Fault Tree Analysis to Bayesian Networks—Part II: Illustration to Microcontroller System
No full textThe vulnerability of microcontroller system against high-altitude electromagnetic pulse (HEMP) is taken as an illustration to demonstrate the assessment methodology based on Bayesian networks (BN). The complete procedure is performed by two steps: the qualitative and the quantitative. The first step focuses on the analysis of three classes of properties, the electromagnetic environment, system function/structure, and their interactions. The primary BN model is built at the end of the first step. The second step investigates the BN nodes and branches one by one, which further implemented through two stages, i.e., the data acquisition and data fusion. The susceptibilities of devises are examined with the pulsed current injection. The responses of the transmission lines to HEMP are computed using the field-line coupling model. Comparing the probability density functions of the electromagnetic stresses and strengths produces the failure probabilities of the interface components. Through two-step analysis, the critical elements and coupling paths are identified and highlighted. After neglecting those unimportant factors, many BN nodes and branches are deleted. Thus, the complexity of assessment is reduced. By assigning the probability values to the simplified BN model, the system failure probability is calculated, which characterizes the system vulnerability against HEMP environment. The illustration validates the rationality and flexibility of the BN assessment methodolog
A review of the 19th International Symposium on geodynamics and earth tide, Wuhan 2021
No full textModern geodetic technologies such as high-precision ground gravity measurements, satellite gravity measurements, the global navigation satellite system, remote sensing methods, etc. provide rich observation data for monitoring various geodynamic processes of the global Earth and its surface. The 19th International Symposium on Geodynamics and Earth Tides brought together scientific researchers from 26 countries around the world, shared the application of various measurements in different geoscience issues, covering Earth tidal deformation, oceanic and atmospheric loading effects, earthquake cycle, hydrology, Earth rotation changes, etc., and provided a precious exchange platform for global peers
Brokerage evolution in innovation contexts: formal structure, network neighborhoods and knowledge
No full textResearch in a number of fields has shown that brokerage is typically fragile while creating consequential outcomes. However, little work has examined the conditions under which brokerage ends, and furthermore, whether and when it terminates with closure in a closed triad that includes the broker, or in a dyad that connects the previously-disconnected alters but disintermediates the broker. We employ a comprehensive theoretical framework drawing on constrained agency to study these questions in a context of organizational innovation. Specifically, we investigate the role of hierarchy, inventors’ network neighborhoods and knowledge differences in shaping the evolution of brokerage. We test our ideas in the a setting of co-patenting in 41 large Chinese research-intensive organizations over the period 1996-2008, with a dataset of 36,338 patents applied for by these organizations. We first show that the type of brokerage ending matters for innovation outcomes by demonstrating that disintermediation creates more subsequent innovativeness than closure. Thereafter, we use a two-step model to first model the termination of brokerage and in the second step to predict the type of closing: disintermediation or closure. Our results show that the broker's and alters’ hierarchical rank similarity promotes disintermediation, as does alters’ connectedness in network neighborhoods, while knowledge differences among the broker and alters encourage the evolution of brokerage toward closure. We spell out the implications of our findings for organizational innovation and the management of R&D
Network Structure, Actor Attributes, and Intraorganizational Knowledge Sharing
No full textHow do the relational and structural characteristics of interpersonal networks affect knowledge sharing within organizations? And how are these effects, in turn, influenced by the personal attributes of the individual network members? To answer these questions, we focus on intraorganizational inventor networks and investigate how tie strength and structural holes influence two major dimensions of knowledge sharing, i.e., knowledge absorption and knowledge transfer. Then we consider the moderating effect of a crucial attribute of inventors, i.e., their status of star inventors. Drawing on patent data from 33 of the largest firms operating in the pharmaceutical industry worldwide during a 34-year time period, we show that both the average tie strength and the proportion of structural holes which characterize inventor networks exert an inverted U-shaped effect on both intraorganizational knowledge absorption and transfer by inventors, and that these four curves become flatten in the case of star inventors, when compared to inventors in genera
Involvement of microRNA-335-5p in cytoskeleton dynamics in mouse oocytes
No full textMicroRNA is a short RNA molecule expressed in eukaryotic cells that is involved in multiple processes, including translational repression, target degradation and gene silencing. However, its specific role(s) in these processes remains largely unknown, especially in terms of germ cell development. The present study identified a microRNA, namely miR-335-5p, that is involved in mouse oocyte meiosis. MiR-335-5p was highly expressed in oocytes, but levels decreased markedly shortly after fertilisation. Microinjection of miR-335-5p or its inhibitor into oocytes resulted in a higher proportion of 2-cell-like MII oocytes and oocytes at the germinal vesicle breakdown and/or MI stage, indicating failure of asymmetric oocyte division. This may be due to regulation of actin because perturbation of miR-335-5p resulted in reduced expression of actin nucleator Daam1, a member of the Formin family. Moreover, injection of miR-335-5p or its inhibitor resulted in aberrant spindle morphology, namely an elongated spindle and multiple poles spindle. After injection of oocytes, levels of phosphorylated extracellular signal-regulated kinase 1/2 (ERK1/2) decreased, suggesting that miR-335-5p may regulate spindle formation via the mitogen-activated protein kinase pathway. Overexpression and inhibition of miR-335-5p had no effect on embryo development. Together, the results of the present study indicate that miR-335-5p is a novel regulator expressed in oocytes that is involved in cytoskeleton dynamics.open
Two new diphenyl ethers from Acanthopanax senticosus (Rupr. & Maxim.) Harms with PTP1B inhibitory activity
No full textBioassay-guided fractionation of an EtOAc-soluble extract of Acanthopanax senticosus (Rupr. & Maxim.) Harms yielded two new diphenyl ethers, 3-[3′-methoxy-4′-(4″-formyl-2″,6′-dimethoxy-phenoxy)-phenyl]-propenal (1) and 3-[3′,5′-dihydroxy-4′-(4″-hydroxymethyl-3″,5″-dimethoxy-phenoxy)-phenyl]-propenal (2), along with eight other known compounds (3-10). The structures of these new ethers were elucidated with spectroscopic and physico-chemical analyses. All of the isolates were evaluated for their in vitro inhibitory activity against PTP1B, VHR and PP1. The new compounds (1 and 2) inhibited PTP1B with IC50 values ranging from 9.2 ± 1.4 to 12.6 ± 1.2 μM.open
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