52 research outputs found
Cutaneous Scar Prevention and Management : Overview of current therapies
Full text linkCutaneous scarring is common after trauma, surgery and infection and occurs when normal skin tissue is replaced by fibroblastic tissue during the healing process. The pathophysiology of scar formation is not yet fully understood, although the degree of tension across the wound edges and the speed of cell growth are believed to play central roles. Prevention of scars is essential and can be achieved by attention to surgical techniques and the use of measures to reduce cell growth. Grading and classifying scars is important to determine available treatment strategies. This article presents an overview of the current therapies available for the prevention and treatment of scars. It is intended to be a practical guide for surgeons and other health professionals involved with and interested in scar management
Mediapipe based Preprocessed VGGFace2 Dataset
No full textVGGFace2 Dataset and Face Mesh PreprocessingIntroductionThe VGGFace2 dataset is a large-scale face recognition dataset containing over 3.31 million images of 9,131 identities, with an average of 362 images per identity. The dataset is designed to include extensive variations in pose, age, illumination, ethnicity, and profession, making it one of the most diverse and challenging face recognition datasets available. For more details, please refer to the original publication:VGGFace2: A dataset for recognizing faces across pose and age - DOI: 10.48550/arXiv.1710.08092
Preprocessing Using MediaPipe 3D Face MeshOn this dataset, we applied the MediaPipe-based 3D face mesh algorithm to accurately detect faces while removing all background elements, including hair. Our preprocessing strictly retained facial landmarks, ensuring that only the essential facial features were preserved. This approach significantly enhanced the accuracy and generalization of our model, as the model was trained exclusively on landmark-based facial data.
Training and PerformanceThe preprocessed data was utilized to train Xception model, which resulted in remarkably accurate outcomes due to the strictly landmark-based facial representation. The model demonstrated robust performance including explainable-AI, proving that eliminating unnecessary background elements contributed positively to its efficiency and reliability.
CitationIf you use this dataset or the preprocessed version in your work, please cite both of the following:
VGGFace2 Dataset:
@article{Cao2018VGGFace2, title={VGGFace2: A dataset for recognizing faces across pose and age}, author={Cao, Qiong and Shen, Li and Xie, Weidi and Parkhi, Omkar M and Zisserman, Andrew}, journal={arXiv preprint arXiv:1710.08092}, year={2018}}
DOI: [10.48550/arXiv.1710.08092](https://doi.org/10.48550/arXiv.1710.08092) Preprocessed Dataset using MediaPipe:@dataset{Shah2025_MediaPipe_FaceMesh, title={MediaPipe-based 3D Face Mesh Preprocessed VGGFace2 Dataset}, author={Shah, Syed Taimoor Hussain and Shah, Syed Adil Hussain and Zamir, Ammara and Qayyum, Kainat and Shah, Syed Baqir Hussain and Fatima, Syeda Maryam and Deriu, Marco Agostino}, year={2025}, doi={10.5281/zenodo.15078557}} DOI: [10.5281/zenodo.15078557](https://doi.org/10.5281/zenodo.15078557)
ContactFor any questions or further details, please feel free to contact us.Syed Taimoor Hussain ShahPolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, ItalyEmail: [email protected]: 0000-0002-6010-677
Cutaneous Scar Prevention and Management : Overview of current therapies
No full textCutaneous scarring is common after trauma, surgery and infection and occurs when normal skin tissue is replaced by fibroblastic tissue during the healing process. The pathophysiology of scar formation is not yet fully understood, although the degree of tension across the wound edges and the speed of cell growth are believed to play central roles. Prevention of scars is essential and can be achieved by attention to surgical techniques and the use of measures to reduce cell growth. Grading and classifying scars is important to determine available treatment strategies. This article presents an overview of the current therapies available for the prevention and treatment of scars. It is intended to be a practical guide for surgeons and other health professionals involved with and interested in scar management
Cranioplasty in Oman: Retrospective review of cases from the National Craniofacial Center 2012–2022
Full text linkObjectives: Cranioplasty is a complex craniofacial and neurosurgical procedure that aims to reinstate the architecture of the cranial vault and elevate both its aesthetic and neurological function. Several reconstructive materials have been thoroughly explored in the search for the optimal solution for cranioplasty. This study aimed to evaluate different material used for cranial reconstruction in Oman. Methods: This retrospective study included all patients who had had cranioplasty procedures performed at Khoula Hospital, Muscat, Oman, from 2012 to 2022. Demographic information, the characteristics of the cranial defect and any complications that occurred post-operatively were analysed. Results: A total of 47 patients were included in this study. The most common cause of cranial defects was craniectomy following traumatic head injury (70.2%) along with excision of fibrous dysplasia (10.6%). The most frequently utilised material for cranial repair was autologous bone grafts (n = 28), followed by polyetheretherketone (PEEK; n = 14). Interestingly, the replacement of bone grafts from previous craniectomy showed a notably high resorption rate (71.4%), in contrast to split calvarial grafts (0%) and other types of bone grafts (14.3%). Additionally, delayed graft infection was observed in 3.6% of the bone graft group and 7.1% of the PEEK group. Conclusion: Patient-specific alloplastic implants such as PEEK have gained popularity for large and complex cranioplasty, as they provide excellent aesthetic outcomes and leave no donor site morbidity. In contrast, bone grafts remain the gold standard for small to medium-sized cranial defects.
Keywords: Bone Grafting; PEEK; Oman
Diyabetik hasta ekstremitelerinde azalmış kan akışını saptamak için empedans pletismografisinin kullanımının araştırılması
No full textThe amount of blood flow into a body tissue is very critical and can be evaluated by monitoring the distention of the blood vessel (artery) feeding that tissue. Several techniques for artery distention monitoring have been reported in the literature. In this study, the impedance plethysmography (IPG) technique has been used as a non-invasive method with multiple electrodes to find the impedance across a finger, and therefore, monitor the existence of blood flow. Simulations have been performed on COMSOL finite element analysis software, and experiments have been carried out to obtain the optimum parameters for this technique. The simulations use 4 electrodes in different positions with a current of 10mA applied throughout a variety of frequencies up to 100 GHz. The resultant data clearly show the advantage of using multiple electrodes to enhance the total information received from the signals, while also indicating that 100Hz can be the optimum frequency for applying IPG. This study demonstrates that IPG with multiple electrodes can be applied to detect the existence of blood flow into body limbs, which is vitally crucial specifically for diabetic patients.Bir vücut dokusuna akan kan miktarı çok önemlidir ve bu dokuyu besleyen kan damarının (arter) şişmesi izlenerek değerlendirilebilir. Literatürde arter distansiyonu izleme için çeşitli teknikler bildirilmiştir. Bu çalışmada empedans pletismografi (IPG) tekniği, bir parmak boyunca empedansı bulmak ve dolayısıyla kan akışının varlığını izlemek için çoklu elektrotlarla invazif olmayan bir yöntem olarak kullanılmıştır. COMSOL sonlu elemanlar analiz yazılımı üzerinde simülasyonlar yapılmış ve bu teknik için optimum parametrelerin elde edilmesi için deneyler yapılmıştır. Simülasyonlar, 100 GHz'e kadar çeşitli frekanslarda uygulanan 10mA akım ile farklı konumlarda 4 elektrot kullanır. Ortaya çıkan veriler, sinyallerden alınan toplam bilgiyi geliştirmek için birden fazla elektrot kullanmanın avantajını açıkça gösterirken, aynı zamanda IPG'yi uygulamak için en uygun frekansın 100 Hz olabileceğini de gösteriyor. Bu çalışma, çoklu elektrotlu IPG'nin, özellikle diyabetik hastalar için hayati önem taşıyan vücut uzuvlarına kan akışının varlığını tespit etmek için uygulanabileceğini göstermektedir.No sponso
Fenofibrate, a drug for COVID-19? All we need to know
Full text linkFenofibrate, a cholesterol-lowering medication, also destabilizes the spike protein on SARS-CoV-2 and prevents it from attaching to human cells. It was efficacious even against SARS-CoV-2 variants investigated in vitro by the researchers.1 According to laboratory tests, a low-cost generic medication decreases SARS-CoV-2 contamination in human cells by up to 70%.2 One medicine that individuals used to regulate cholesterol levels might be an effective therapy against COVID-19, according to a multinational initiative comprising scientists from San Raffaele Scientific Institute in Milan, University of Birmingham, and the University of Keele in the United Kingdom. The study's findings will be published in the journal Frontiers in Pharmacology.1,2
In the beginning, researchers tested a number of approved medicines on animals. For COVID-19 therapy, they were seeking medicines that disrupted interactions between the viral spike protein and human cell surface. Dr. Alan Richardson, a co-author of the study, told a source that they have evaluated above 100 medicines and discovered that fibric acids had the most potential. Fenofibrate proved to be a better alternative to clofibrate because of its unfavorable side effects.”3 Fenofibrate was developed by scientists in the 1980s, and it was frequently prescribed by Physicians to lower cholesterol levels in patients.2 It was incredibly popular, until statins were discovered, to reduce the risk of heart disease. Statins are currently taken by over 30 million people in the United States and throughout the world. Fenofibrate, on the other hand, is used by patients who cannot tolerate statins.4
Currently, the medication is efficacious against the Beta and Alpha strains of SARS-CoV-2, and the team is researching its efficacy against the Delta variant nowadays. “\Resistance will be tougher to develop since the medication hits several targets, not only the spike protein, thus future variations should not be able to escape the effect.2 Fenofibrate was shown to be just as efficient against a live virus as the isolated protein.3 Dr. Farhat Khanim, a co-author of the paper, tested the medication against a live virus. She had high hopes for it. The scientists are cautiously and extremely enthusiastic about the possibilities. They further opined that we must not lose sight of the reality that there are high-risk categories of individuals for whom the vaccination will not function. In order to treat SARS-CoV-2, we must urgently increase our arsenal of medicines.4<br>According to Dr. Khanim: “The medication appears to work, regardless of spike mutations.”4
When infected cells were given fenofibrate in vitro, the researchers looked at the amount of virus that was released from them. When compared to untreated cells, they discovered that viral release was reduced by 60%. Statins, for example, did not have the same impact.5
Fascinatingly, fenofibrate can be taken orally and is extremely inexpensive, so if scientists duplicate the findings in clinical trials, it might be helpful for poor and medium-income countries that have struggled with vaccinations in the past. Fenofibrate is readily available, according to the estimates, a course of therapy would cost between £10 and £20.6
If this in vitro result translates into a beneficial clinical impact, it may add another medication to our arsenal, according to Dr. Peter English. This is all theoretical at the moment, he says, because the medication hasn't been tested outside of the laboratory yet. The study's authors urge caution in interpreting their conclusions because they are based on laboratory experiments. For COVID-19, they are eager to begin clinical studies with fenofibrate.7
As Dr. Khanim told, “I'd want to see clinical studies in high-risk people in the community with symptoms, initiating therapy early to see whether it reduces hospitalization.”2
 
Proboscis lateralis: A case report of a rare giant craniofacial teratoma in an infant
Full text linkTeratomas can occur in almost any region of the body and are the most common extragonadal germ cell childhood tumors. However, craniofacial teratomas are rare. Craniofacial teratomas can present unique features and cause significant functional and aesthetic concerns. There are complex lesions that can have components intra-cranially and extra-cranially. Therefore, their management requires significant multi-stage multidisciplinary surgical procedures. Herein, we present a case of craniofacial teratoma in a child with the phenotype of proboscis lateralis that highlights some of the pertinent point of the diagnosis and management of congenital neonatal teratomas
Fast and low loss flexoelectro-optic liquid crystal phase modulator with a chiral nematic reflector
Full text link© 2019, The Author(s). In this paper, we demonstrate a flexoelectro-optic liquid crystal phase-only device that uses a chiral nematic reflector to achieve full 2π phase modulation. This configuration is found to be very tolerant to imperfections in the chiral nematic reflector provided that the flexoelectro-optic LC layer fulfils the half-wave condition. Encouragingly, the modulation in the phase, which operates at kHz frame rates, is also accompanied by low amplitude modulation. The configuration demonstrated herein is particularly promising for the development of next-generation liquid crystal on silicon spatial light modulators
Bibliometric estimation of research productivity, published in the European Journal of International Law from 2006 – 2019
Full text linkIntroduction of study: This study portrays the European Journal of International Law\u27s published data from 2006 - 2019, indexed in the Scopus-Elsevier database.
Methodology: The retrieved data tabulated in MS Office Excel Sheet. The author\u27s role and collaboration, type of documents, and association of the first author with the country aimed to explore the issue and year wise frequency of publications.
Results: Total 739 documents published and distributed in seven categories original articles 582; 78.7%, followed by 59; 8% review articles and 56; 7.5% editorials got the top slot in the publications. Single or solo authors wrote the documents produced by 841; 1.1% authors, majority 621; 84%; research papers. The affiliation of the first author belongs to forty-three countries. In this study, The United Kingdom on the top slot with 147; 19.8% publications, followed by United States 119; 16.1%, and Italy 118; 16%. Twelve articles published in random years got a maximum of 348 and a minimum of 100 citations.
Conclusion: The European Journal of International Law regularly publishes a consistent approach and promotes international law writings. This journal\u27s dynamic is the facilitation of translations from French, Spanish, Italian and German languages to the English language
- …
